| 1 |
35618653 | A ROS-Responsive Simvastatin Nano-Prodrug and its Fibronectin-Targeted Co-Delivery System for Atherosclerosis Treatment. | 2022 Jun 8 |
1 |
| 2 |
33864447 | Excessive expression of miR-1a by statin causes skeletal injury through targeting mitogen-activated protein kinase kinase kinase 1. | 2021 Apr 16 |
1 |
| 3 |
34349106 | Simvastatin therapy attenuates memory deficits that associate with brain monocyte infiltration in chronic hypercholesterolemia. | 2021 Aug 4 |
1 |
| 4 |
34422919 | Inhibition of Rac1 GTPase Decreases Vascular Oxidative Stress, Improves Endothelial Function, and Attenuates Atherosclerosis Development in Mice. | 2021 |
1 |
| 5 |
30713570 | Yangyin Qingre Huoxue Method in Traditional Chinese Medicine Ameliorates Atherosclerosis in ApoE-/- Mice Suffering from High-Fat Diet and HSP65 Aggression. | 2019 |
1 |
| 6 |
31731717 | Lunasin Improves the LDL-C Lowering Efficacy of Simvastatin via Inhibiting PCSK9 Expression in Hepatocytes and ApoE-/- Mice. | 2019 Nov 15 |
2 |
| 7 |
29735887 | Ursolic Acid Attenuates Atherosclerosis in ApoE-/- Mice: Role of LOX-1 Mediated by ROS/NF-κB Pathway. | 2018 May 7 |
1 |
| 8 |
27091343 | Asymmetric Dimethylarginine Limits the Efficacy of Simvastatin Activating Endothelial Nitric Oxide Synthase. | 2016 Apr 18 |
1 |
| 9 |
26295063 | Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation. | 2015 Apr |
2 |
| 10 |
24998652 | [Effect of simvastatin on atherosclerosis and central aortic pressure in ApoE gene knockout mice]. | 2014 May |
2 |
| 11 |
23564080 | Simvastatin suppresses vascular inflammation and atherosclerosis in ApoE(-/-) mice by downregulating the HMGB1-RAGE axis. | 2013 Jun |
3 |
| 12 |
24080182 | Simvastatin increases Prolyl-4-Hydroxylase α1 expression in atherosclerotic plaque and ox-LDL-stimulated human aortic smooth muscle cells via p38 MAPK and ERK1/2 signaling. | 2013 Dec |
1 |
| 13 |
22038096 | Simvastatin suppresses apoptosis in vulnerable atherosclerotic plaques through regulating the expression of p(53), Bcl-2 and Bcl-xL. | 2012 Feb |
2 |
| 14 |
22977450 | Simvastatin and losartan differentially and synergistically inhibit atherosclerosis in apolipoprotein e(-/-) mice. | 2012 Aug |
1 |
| 15 |
23216643 | Inhibitory effect of the combination therapy of simvastatin and pinocembrin on atherosclerosis in ApoE-deficient mice. | 2012 Dec 5 |
2 |
| 16 |
21241519 | Simvastatin reduces atherogenesis and promotes the expression of hepatic genes associated with reverse cholesterol transport in apoE-knockout mice fed high-fat diet. | 2011 Jan 18 |
3 |
| 17 |
19639539 | Rhein improves renal lesion and ameliorates dyslipidemia in db/db mice with diabetic nephropathy. | 2010 Jan |
1 |
| 18 |
20809215 | Efficacy of simvastatin in reducing aortic dilatation in mouse models of abdominal aortic aneurysm. | 2010 Dec |
1 |
| 19 |
19729613 | Simvastatin inhibits angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-knockout mice: possible role of ERK. | 2009 Nov |
2 |
| 20 |
19738398 | Effects of simvastatin on plasma lipoproteins and hearing loss in apolipoprotein E gene-deficient mice. | 2009 |
1 |
| 21 |
18295249 | Effect of simvastatin in apolipoprotein E deficient mice with surgically induced chronic renal failure. | 2008 Apr |
1 |
| 22 |
18443364 | Diabetes reduces aortic endothelial gap junctions in ApoE-deficient mice: simvastatin exacerbates the reduction. | 2008 Aug |
1 |
| 23 |
19578502 | Circulating Markers Reflect Both Anti- and Pro-Atherogenic Drug Effects in ApoE-Deficient Mice. | 2008 Mar 12 |
1 |
| 24 |
17214935 | [Effects of water extractives of a qi and blood regulating prescription on early atherosclerosis of apolipoprotein E-deficient mice]. | 2007 Jan |
1 |
| 25 |
16460674 | Simvastatin causes the formation of cholesterol-rich remnants in mice lacking apoE. | 2006 Mar 24 |
3 |
| 26 |
16920939 | Simvastatin treatment ameliorates autoimmune disease associated with accelerated atherosclerosis in a murine lupus model. | 2006 Sep 1 |
3 |
| 27 |
15639308 | Cardiovascular functional phenotypes and pharmacological responses in apolipoprotein E deficient mice. | 2005 Mar |
1 |
| 28 |
14752252 | Effects of simvastatin on plasma lipoproteins and response to arterial injury in wild-type and apolipoprotein-E-deficient mice. | 2004 Jan-Feb |
2 |
| 29 |
15300198 | Aortic eNOS expression and phosphorylation in Apo-E knockout mice: differing effects of rapamycin and simvastatin. | 2004 Aug |
1 |
| 30 |
15572054 | Simvastatin enhances myocardial angiogenesis induced by vascular endothelial growth factor gene transfer. | 2004 Dec |
3 |
| 31 |
12818400 | Simvastatin inhibits expression of tissue factor in advanced atherosclerotic lesions of apolipoprotein E deficient mice independently of lipid lowering: potential role of simvastatin-mediated inhibition of Egr-1 expression and activation. | 2003 Apr |
2 |
| 32 |
11947894 | Anti-atherosclerotic effect of simvastatin depends on the presence of apolipoprotein E. | 2002 May |
2 |
| 33 |
12426212 | Simvastatin promotes atherosclerotic plaque stability in apoE-deficient mice independently of lipid lowering. | 2002 Nov 1 |
2 |
| 34 |
11382730 | Simvastatin exerts both anti-inflammatory and cardioprotective effects in apolipoprotein E-deficient mice. | 2001 May 29 |
3 |