Bexarotene

apolipoprotein E ; Mus musculus







21 Article(s)
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Pub. Year
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1 33099295 Inhibition of MAPT enhances the effect of bexarotene and attenuates the damage after traumatic brain injury using in vivo and in vitro experiments. 2020 1
2 29995422 Retinoid X Receptor Alpha Nitro-ligand Z-10 and Its Optimized Derivative Z-36 Reduce β-Amyloid Plaques in Alzheimer's Disease Mouse Model. 2019 Feb 4 1
3 31055081 Astaxanthin exerts protective effects similar to bexarotene in Alzheimer's disease by modulating amyloid-beta and cholesterol homeostasis in blood-brain barrier endothelial cells. 2019 Sep 1 1
4 31596896 Bexarotene therapy ameliorates behavioral deficits and induces functional and molecular changes in very-old Triple Transgenic Mice model of Alzheimer´s disease. 2019 2
5 27235741 Bexarotene protects against traumatic brain injury in mice partially through apolipoprotein E. 2017 Feb 20 2
6 27842487 Possible Molecular Interactions of Bexarotene - A Retinoid Drug and Alzheimer's Aβ Peptide: A Docking Study. 2017 2
7 28689412 Bexarotene Does Not Clear Amyloid Beta Plaques but Delays Fibril Growth: Molecular Mechanisms. 2017 Sep 20 2
8 26175148 ABCA1 is Necessary for Bexarotene-Mediated Clearance of Soluble Amyloid Beta from the Hippocampus of APP/PS1 Mice. 2016 Mar 3
9 26688581 Rescuing effects of RXR agonist bexarotene on aging-related synapse loss depend on neuronal LRP1. 2016 Mar 3
10 27051978 RXR controlled regulatory networks identified in mouse brain counteract deleterious effects of Aβ oligomers. 2016 Apr 7 1
11 25630951 Combined treatment with bexarotene and rosuvastatin reduces angiotensin-II-induced abdominal aortic aneurysm in apoE(-/-) mice and angiogenesis. 2015 Jun 1
12 25777514 The Continuing Failure of Bexarotene in Alzheimer's Disease Mice. 2015 2
13 26085639 Omega-3 Fatty Acids Augment the Actions of Nuclear Receptor Agonists in a Mouse Model of Alzheimer's Disease. 2015 Jun 17 1
14 24599963 Retinoic acid isomers facilitate apolipoprotein E production and lipidation in astrocytes through the retinoid X receptor/retinoic acid receptor pathway. 2014 Apr 18 4
15 24849361 Reversal of apoE4-driven brain pathology and behavioral deficits by bexarotene. 2014 May 21 1
16 25164224 [Effects and related mechanism of retinoid X receptor agonist bexarotene on atherosclerosis progression in diabetic apoE(-/-) mice]. 2014 Jun 1
17 25217640 Amyloid-β pathology and APOE genotype modulate retinoid X receptor agonist activity in vivo. 2014 Oct 31 3
18 23601557 In vivo measurement of apolipoprotein E from the brain interstitial fluid using microdialysis. 2013 Apr 19 1
19 23764200 Treatment with bexarotene, a compound that increases apolipoprotein-E, provides no cognitive benefit in mutant APP/PS1 mice. 2013 Jun 13 1
20 24047423 New hope from an old drug: fighting Alzheimer's disease with the cancer drug bexarotene (targretin)? 2013 Dec 2
21 22323736 ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models. 2012 Mar 23 1