Metformin

apolipoprotein E ; Mus musculus







23 Article(s)
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Pub. Year
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1 35090900 Metformin alleviates the depression-like behaviors of elderly apoE4 mice via improving glucose metabolism and mitochondrial biogenesis. 2022 Apr 9 1
2 35196199 Treatments targeting autophagy ameliorate the age-related macular degeneration phenotype in mice lacking APOE (apolipoprotein E). 2022 Feb 23 1
3 32667970 Metformin directly suppresses atherosclerosis in normoglycaemic mice via haematopoietic adenosine monophosphate-activated protein kinase. 2021 Apr 23 1
4 33915432 Metformin attenuates atherosclerosis and plaque vulnerability by upregulating KLF2-mediated autophagy in apoE-/- mice. 2021 Jun 11 3
5 34264978 Metformin intervention ameliorates AS in ApoE-/- mice through restoring gut dysbiosis and anti-inflammation. 2021 1
6 34368251 Metformin Suppresses the Progress of Diabetes-Accelerated Atherosclerosis by Inhibition of Vascular Smooth Muscle Cell Migration Through AMPK-Pdlim5 Pathway. 2021 2
7 31955370 Metformin Delays the Development of Atherosclerosis in Type 1 Diabetes Mellitus via the Methylglyoxal Pathway. 2020 Mar 1
8 33411680 Overexpression of long noncoding RNA ANRIL inhibits phenotypic switching of vascular smooth muscle cells to prevent atherosclerotic plaque development in vivo. 2020 Dec 19 2
9 30894020 Metformin treatment improves the spatial memory of aged mice in an APOE genotype-dependent manner. 2019 Jun 4
10 30909226 Metformin Therapy Aggravates Neurodegenerative Processes in ApoE-/- Mice. 2019 2
11 31467666 Metformin represses the pathophysiology of AAA by suppressing the activation of PI3K/AKT/mTOR/autophagy pathway in ApoE-/- mice. 2019 1
12 31518877 Metformin inhibited Nod-like receptor protein 3 inflammasomes activation and suppressed diabetes-accelerated atherosclerosis in apoE-/- mice. 2019 Nov 2
13 29366775 Metformin regulates mitochondrial biogenesis and senescence through AMPK mediated H3K79 methylation: Relevance in age-associated vascular dysfunction. 2018 Apr 1
14 29499335 Metformin treatment prevents SREBP2-mediated cholesterol uptake and improves lipid homeostasis during oxidative stress-induced atherosclerosis. 2018 Apr 2
15 29502204 AMPKα inactivation destabilizes atherosclerotic plaque in streptozotocin-induced diabetic mice through AP-2α/miRNA-124 axis. 2018 May 1
16 27737949 Metformin Suppresses Diabetes-Accelerated Atherosclerosis via the Inhibition of Drp1-Mediated Mitochondrial Fission. 2017 Jan 2
17 28145471 Synergistic effects of metformin with liraglutide against endothelial dysfunction through GLP-1 receptor and PKA signalling pathway. 2017 Feb 1 1
18 26712380 Influence of metformin on mitochondrial subproteome in the brain of apoE knockout mice. 2016 Feb 5 2
19 27256105 Ablation of Adenosine Monophosphate-Activated Protein Kinase α1 in Vascular Smooth Muscle Cells Promotes Diet-Induced Atherosclerotic Calcification In Vivo. 2016 Jul 22 1
20 25552600 Metformin inhibits monocyte-to-macrophage differentiation via AMPK-mediated inhibition of STAT3 activation: potential role in atherosclerosis. 2015 Jun 2
21 25527624 Metformin beyond diabetes: pleiotropic benefits of metformin in attenuation of atherosclerosis. 2014 Dec 1
22 23531341 Proteomic and functional annotation analysis of injured peripheral nerves reveals ApoE as a protein upregulated by injury that is modulated by metformin treatment. 2013 Mar 26 1
23 22960565 Proteomic analysis of liver mitochondria of apolipoprotein E knockout mice treated with metformin. 2012 Dec 21 3