Reactive Oxygen Species

apolipoprotein E ; Mus musculus







46 Article(s)
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1 35016995 Traffic-generated air pollution - Exposure mediated expression of factors associated with demyelination in a female apolipoprotein E-/- mouse model. 2022 Mar-Apr 1
2 35269673 Doxycycline Decreases Atherosclerotic Lesions in the Aorta of ApoE-⁄- and Ovariectomized Mice with Correlation to Reduced MMP-2 Activity. 2022 Feb 25 1
3 35493076 Chlamydia pneumoniae Infection Induces Vascular Smooth Muscle Cell Migration and Atherosclerosis Through Mitochondrial Reactive Oxygen Species-Mediated JunB-Fra-1 Activation. 2022 2
4 32533834 Endothelium-restricted endothelin-1 overexpression in type 1 diabetes worsens atherosclerosis and immune cell infiltration via NOX1. 2021 Mar 21 3
5 34869701 Association of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 With Angiotensin II Type 1 Receptor Impacts Mitochondrial Quality Control, Offering Promise for the Treatment of Vascular Senescence. 2021 1
6 31634818 Pharmacological inhibition of histone deacetylase reduces NADPH oxidase expression, oxidative stress and the progression of atherosclerotic lesions in hypercholesterolemic apolipoprotein E-deficient mice; potential implications for human atherosclerosis. 2020 Jan 1
7 32132319 Toll-Like Receptor 7 Stimulation Promotes the Development of Atherosclerosis in Apolipoprotein E-Deficient Mice. 2020 Mar 28 3
8 31422047 Critical Limb Ischaemia Exacerbates Mitochondrial Dysfunction in ApoE-/- Mice Compared with ApoE+/+ Mice, but N-acetyl Cysteine still Confers Protection. 2019 Oct 1
9 29225168 Cortistatin attenuates angiotensin II-induced abdominal aortic aneurysm through inactivation of the ERK1/2 signaling pathways. 2018 Jan 8 1
10 30165101 TRAIL protects against endothelial dysfunction in vivo and inhibits angiotensin-II-induced oxidative stress in vascular endothelial cells in vitro. 2018 Oct 1
11 30342191 Attenuation of oxidative stress-induced lesions in skeletal muscle in a mouse model of obesity-independent hyperlipidaemia and atherosclerosis through the inhibition of Nox2 activity. 2018 Dec 1
12 28177681 Icariin improves eNOS/NO pathway to prohibit the atherogenesis of apolipoprotein E-null mice. 2017 Jun 1
13 28970293 Mitochondrial Respiration Is Reduced in Atherosclerosis, Promoting Necrotic Core Formation and Reducing Relative Fibrous Cap Thickness. 2017 Dec 1
14 29079564 Attenuated Superoxide Dismutase 2 Activity Induces Atherosclerotic Plaque Instability During Aging in Hyperlipidemic Mice. 2017 Oct 27 1
15 29100334 Paradoxical effects of 137Cs irradiation on pharmacological stimulation of reactive oxygen species in hippocampal slices from apoE2 and apoE4 mice. 2017 Sep 29 2
16 26751387 Proinflammatory Stimulation of Toll-Like Receptor 9 with High Dose CpG ODN 1826 Impairs Endothelial Regeneration and Promotes Atherosclerosis in Mice. 2016 1
17 25496431 NOX1 deficiency in apolipoprotein E-knockout mice is associated with elevated plasma lipids and enhanced atherosclerosis. 2015 Feb 2
18 25675483 Contribution of reactive oxygen species to cerebral amyloid angiopathy, vasomotor dysfunction, and microhemorrhage in aged Tg2576 mice. 2015 Feb 24 1
19 25860063 Mechanisms of enhanced vasoconstriction in the mouse model of atherosclerosis: the beneficial effects of sildenafil. 2015 3
20 26054376 NOX4 NADPH Oxidase-Dependent Mitochondrial Oxidative Stress in Aging-Associated Cardiovascular Disease. 2015 Dec 20 2
21 24191281 Angiotensin-(1-7) modulates renal vascular resistance through inhibition of p38 mitogen-activated protein kinase in apolipoprotein E-deficient mice. 2014 Feb 2
22 24292634 Pharmacological inhibition of NOX reduces atherosclerotic lesions, vascular ROS and immune-inflammatory responses in diabetic Apoe(-/-) mice. 2014 Mar 2
23 24511132 Genetic targeting or pharmacologic inhibition of NADPH oxidase nox4 provides renoprotection in long-term diabetic nephropathy. 2014 Jun 1
24 24612630 An increased arginase activity is associated with corpus cavernosum impairment induced by hypercholesterolemia. 2014 May 1
25 25164224 [Effects and related mechanism of retinoid X receptor agonist bexarotene on atherosclerosis progression in diabetic apoE(-/-) mice]. 2014 Jun 1
26 23385237 Effects of Aging and Hypercholesterolemia on Oxidative Stress and DNA Damage in Bone Marrow Mononuclear Cells in Apolipoprotein E-deficient Mice. 2013 Feb 5 1
27 23415688 BRCA1 is a novel target to improve endothelial dysfunction and retard atherosclerosis. 2013 Oct 1
28 23887640 Endothelin-1 overexpression exacerbates atherosclerosis and induces aortic aneurysms in apolipoprotein E knockout mice. 2013 Oct 2
29 24045154 The transcription factor CREB enhances interleukin-17A production and inflammation in a mouse model of atherosclerosis. 2013 Sep 17 1
30 22253482 Toll-like receptor-4 mediates obesity-induced non-alcoholic steatohepatitis through activation of X-box binding protein-1 in mice. 2012 Jul 2
31 22282402 Ginkgo biloba extract (GbE) enhances the anti-atherogenic effect of cilostazol by inhibiting ROS generation. 2012 May 31 2
32 22401921 Apolipoprotein e genotype-dependent paradoxical short-term effects of (56)fe irradiation on the brain. 2012 Nov 1 1
33 22547655 HSP90 inhibition by 17-DMAG attenuates oxidative stress in experimental atherosclerosis. 2012 Jul 1 1
34 22613987 Panax notogingseng saponins suppress RAGE/MAPK signaling and NF-kappaB activation in apolipoprotein-E-deficient atherosclerosis-prone mice. 2012 1
35 22814241 NADPH oxidase 2-derived reactive oxygen species are involved in dysfunction and apoptosis of pancreatic β-cells induced by low density lipoprotein. 2012 1
36 21330604 Cyclophilin A promotes cardiac hypertrophy in apolipoprotein E-deficient mice. 2011 May 4
37 21873804 The antioxidant N-acetylcysteine promotes atherosclerotic plaque stabilization through suppression of RAGE, MMPs and NF-κB in ApoE-deficient mice. 2011 1
38 21884703 Atheroprotection via cannabinoid receptor-2 is mediated by circulating and vascular cells in vivo. 2011 Dec 1
39 19546345 Effects of oral estrogen on aortic ROS-generating and -scavenging enzymes and atherosclerosis in apoE-deficient mice. 2009 Sep 1
40 17965457 Inactivation of human liver bile acid CoA:amino acid N-acyltransferase by the electrophilic lipid, 4-hydroxynonenal. 2008 Feb 1
41 18252813 Antiatherosclerotic effects of small-molecular-weight compounds enhancing endothelial nitric-oxide synthase (eNOS) expression and preventing eNOS uncoupling. 2008 May 1
42 18976655 Regulatory role of thioredoxin in homocysteine-induced monocyte chemoattractant protein-1 secretion in monocytes/macrophages. 2008 Nov 26 1
43 17005918 The nitric oxide-donating pravastatin derivative, NCX 6550 [(1S-[1alpha(betaS*, deltaS*), 2alpha, 6alpha, 8beta-(R*), 8a alpha]]-1,2,6,7,8,8a-Hexahydro-beta, delta, 6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphtalene-heptanoic acid 4-(nitrooxy)butyl ester)], reduces splenocyte adhesion and reactive oxygen species generation in normal and atherosclerotic mice. 2007 Jan 2
44 15264223 Effects of apolipoprotein E on the human immunodeficiency virus protein Tat in neuronal cultures and synaptosomes. 2004 Aug 15 1
45 11922914 Oxidant stress mechanism of homocysteine potentiating Con A-induced proliferation in murine splenic T lymphocytes. 2002 Mar 1
46 10737615 Amyloid beta-peptide effects on synaptosomes from apolipoprotein E-deficient mice. 2000 Apr 1