| 1 |
33993848 | AHCYL1 senses SAH to inhibit autophagy through interaction with PIK3C3 in an MTORC1-independent manner. | 2022 Feb |
4 |
| 2 |
34119876 | Epigenetic regulation of TXNIP-mediated oxidative stress and NLRP3 inflammasome activation contributes to SAHH inhibition-aggravated diabetic nephropathy. | 2021 Sep |
1 |
| 3 |
32408898 | Acquired resistance to DZNep-mediated apoptosis is associated with copy number gains of AHCY in a B-cell lymphoma model. | 2020 May 14 |
1 |
| 4 |
33035507 | 3-Deazaadenosine, an S-adenosylhomocysteine hydrolase inhibitor, attenuates lipopolysaccharide-induced inflammatory responses via inhibition of AP-1 and NF-κB signaling. | 2020 Dec |
2 |
| 5 |
31265905 | Inhibition of juvenile hormone synthesis in mosquitoes by the methylation inhibitor 3-deazaneplanocin A (DZNep). | 2019 Oct |
3 |
| 6 |
30228286 | Knock-down of AHCY and depletion of adenosine induces DNA damage and cell cycle arrest. | 2018 Sep 18 |
1 |
| 7 |
27623281 | A new s-adenosylhomocysteine hydrolase-linked method for adenosine detection based on DNA-templated fluorescent Cu/Ag nanoclusters. | 2017 Jul 15 |
3 |
| 8 |
28533090 | Identification of AHCY inhibitors using novel high-throughput mass spectrometry. | 2017 Sep 9 |
2 |
| 9 |
28705714 | Aristeromycin and DZNeP cause growth inhibition of prostate cancer via induction of mir-26a. | 2017 Oct 5 |
2 |
| 10 |
28933241 | Characterization of human S-adenosyl-homocysteine hydrolase in vitro and identification of its potential inhibitors. | 2017 Dec |
4 |
| 11 |
26037610 | Discovery and structural analyses of S-adenosyl-L-homocysteine hydrolase inhibitors based on non-adenosine analogs. | 2015 Aug 1 |
3 |
| 12 |
26328244 | Inhibition of S-adenosylhomocysteine hydrolase decreases cell mobility and cell proliferation through cell cycle arrest. | 2015 |
1 |
| 13 |
26573329 | Structural insights into the reaction mechanism of S-adenosyl-L-homocysteine hydrolase. | 2015 Nov 17 |
4 |
| 14 |
24813734 | Adenosine analogue inhibitors of S-adenosylhomocysteine hydrolase. | 2014 Jun 15 |
3 |
| 15 |
24914852 | Thymine-based molecular beacon for sensing adenosine based on the inhibition of S-adenosylhomocysteine hydrolase activity. | 2014 Nov 15 |
6 |
| 16 |
25248746 | Regulation of S-adenosylhomocysteine hydrolase by lysine acetylation. | 2014 Nov 7 |
2 |
| 17 |
23017368 | S-adenosyl-L-homocysteine hydrolase and methylation disorders: yeast as a model system. | 2013 Jan |
1 |
| 18 |
23040372 | A method for fluorescence sensing of adenosine and alkaline phosphatase based on the inhibition of S-adenosylhomocysteine hydrolase activity. | 2013 Mar 15 |
6 |
| 19 |
23079506 | A fluorescence-based assay for the measurement of S-adenosylhomocysteine hydrolase activity in biological samples. | 2013 Feb 15 |
1 |
| 20 |
22349223 | High-resolution structures of complexes of plant S-adenosyl-L-homocysteine hydrolase (Lupinus luteus). | 2012 Mar |
2 |
| 21 |
20945873 | Colorimetric assay for S-adenosylhomocysteine hydrolase activity and inhibition using fluorosurfactant-capped gold nanoparticles. | 2010 Nov 1 |
5 |
| 22 |
18769049 | S-Adenosylhomocysteine hydrolase overexpression in HEK-293 cells: effect on intracellular adenosine levels, cell viability, and DNA methylation. | 2008 |
4 |
| 23 |
18815415 | Crystal structures of Mycobacterium tuberculosis S-adenosyl-L-homocysteine hydrolase in ternary complex with substrate and inhibitors. | 2008 Dec |
3 |
| 24 |
17069857 | Molecular insights of SAH enzyme catalysis and implication for inhibitor design. | 2007 Feb 21 |
2 |
| 25 |
17097637 | Role of S-adenosylhomocysteine hydrolase in adenosine-induced apoptosis in HepG2 cells. | 2007 Jan 15 |
1 |
| 26 |
17164794 | Functional analysis of human S-adenosylhomocysteine hydrolase isoforms SAHH-2 and SAHH-3. | 2007 Mar |
2 |
| 27 |
17845853 | The antiviral drug ribavirin is a selective inhibitor of S-adenosyl-L-homocysteine hydrolase from Trypanosoma cruzi. | 2007 Dec 1 |
3 |
| 28 |
17850795 | Homocysteine-induced endothelial cell adhesion is related to adenosine lowering and is not mediated by S-adenosylhomocysteine. | 2007 Oct 2 |
1 |
| 29 |
17172447 | S-adenosylhomocysteine hydrolase is localized at the front of chemotaxing cells, suggesting a role for transmethylation during migration. | 2006 Dec 26 |
2 |
| 30 |
16061414 | Catalytic mechanism of S-adenosylhomocysteine hydrolase: roles of His 54, Asp130, Glu155, Lys185, and Aspl89. | 2005 Nov |
2 |
| 31 |
16149054 | Mitochondrial mechanism of oxidative stress and systemic hypertension in hyperhomocysteinemia. | 2005 Nov 1 |
2 |
| 32 |
16197289 | Effects of homocysteine on vascular and tissue adenosine: a stake in homocysteine pathogenicity? | 2005 |
1 |
| 33 |
15165742 | S-Adenosylhomocysteine hydrolase as a target for intracellular adenosine action. | 2004 Jun |
5 |
| 34 |
12910461 | Structure, evolution, and inhibitor interaction of S-adenosyl-L-homocysteine hydrolase from Plasmodium falciparum. | 2003 Sep 1 |
1 |
| 35 |
11927587 | Catalytic mechanism of S-adenosylhomocysteine hydrolase. Site-directed mutagenesis of Asp-130, Lys-185, Asp-189, and Asn-190. | 2002 Jun 21 |
2 |
| 36 |
12036374 | Sugar-modified conjugated diene analogues of adenosine and uridine: synthesis, interaction with S-adenosyl-L-homocysteine hydrolase, and antiviral and cytostatic effects. | 2002 Jun 6 |
1 |
| 37 |
10737751 | Doubly homologated dihalovinyl and acetylene analogues of adenosine: synthesis, interaction with S-adenosyl-L-homocysteine hydrolase, and antiviral and cytostatic effects. | 2000 Mar 23 |
1 |
| 38 |
11325033 | Structure and function of S-adenosylhomocysteine hydrolase. | 2000 |
2 |
| 39 |
9708366 | Carbocyclic adenosine analogues as S-adenosylhomocysteine hydrolase inhibitors and antiviral agents: recent advances. | 1998 Jan-Mar |
1 |
| 40 |
9171871 | Anticancer and antiviral effects and inactivation of S-adenosyl-L-homocysteine hydrolase with 5'-carboxaldehydes and oximes synthesized from adenosine and sugar-modified analogues. | 1997 May 23 |
1 |
| 41 |
8093102 | Effects of novel anti-viral adenosine analogues on the activity of S-adenosylhomocysteine hydrolase from human liver. | 1994 Aug 30 |
1 |
| 42 |
8261422 | Z-4',5'-didehydro-5'-deoxy-5'-fluoroadenosine (MDL 28,842), an irreversible inhibitor of S-adenosylhomocysteine hydrolase, suppresses proliferation of cultured keratinocytes and squamous carcinoma cell lines. | 1993 Dec 15 |
1 |
| 43 |
8384443 | Mechanisms of elevation of adenosine levels in anoxic hepatocytes. | 1993 Mar 15 |
1 |
| 44 |
8416969 | S-adenosylhomocysteine hydrolase. Stereochemistry and kinetics of hydrogen transfer. | 1993 Jan 5 |
2 |
| 45 |
1737776 | Reduced S-adenosylhomocysteine hydrolase. Kinetics and thermodynamics for binding of 3'-ketoadenosine, adenosine, and adenine. | 1992 Feb 15 |
2 |
| 46 |
2244927 | Influence of S-adenosylhomocysteine hydrolase inhibitors on S-adenosylhomocysteine and S-adenosylmethionine pool levels in L929 cells. | 1990 Nov 15 |
1 |
| 47 |
2785825 | ATP formation from deoxyadenosine in human erythrocytes: evidence for a hitherto unidentified route involving adenine and S-adenosylhomocysteine hydrolase. | 1989 Feb |
1 |
| 48 |
3574293 | Adenosine dialdehyde: a potent inhibitor of vaccinia virus multiplication in mouse L929 cells. | 1987 May |
1 |
| 49 |
3457563 | 3-Deazaneplanocin: a new and potent inhibitor of S-adenosylhomocysteine hydrolase and its effects on human promyelocytic leukemia cell line HL-60. | 1986 Mar 13 |
1 |
| 50 |
3741629 | Specific enzymatic assay method for homocysteine and its application to the screening of neonatal homocystinuria. | 1986 Apr-Jun |
1 |