| 1 |
32101568 | KLF4 is required for suppression of histamine synthesis by polyamines during bone marrow-derived mast cell differentiation. | 2020 |
2 |
| 2 |
32911426 | Targeting polyamine as a novel therapy in xenograft models of malignant pleural mesothelioma. | 2020 Oct |
2 |
| 3 |
33244237 | Simultaneous Inhibition of Ornithine Decarboxylase 1 and Pyruvate Kinase M2 Exerts Synergistic Effects Against Hepatocellular Carcinoma Cells. | 2020 |
1 |
| 4 |
33403098 | Inhibition of ornithine decarboxylase restores hypoxic pulmonary vasoconstriction in endotoxemic mice. | 2020 Oct-Dec |
1 |
| 5 |
30700572 | Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma. | 2019 Jan 30 |
2 |
| 6 |
30927735 | α-Difluoromethylornithine suppresses inflammatory arthritis by impairing myeloid-derived suppressor cells. | 2019 Jun |
4 |
| 7 |
31088836 | DFMO and 5-Azacytidine Increase M1 Macrophages in the Tumor Microenvironment of Murine Ovarian Cancer. | 2019 Jul 1 |
2 |
| 8 |
29635516 | Metabolomic studies identify changes in transmethylation and polyamine metabolism in a brain-specific mouse model of tuberous sclerosis complex. | 2018 Jun 15 |
1 |
| 9 |
29240775 | Ornithine decarboxylase as a therapeutic target for endometrial cancer. | 2017 |
3 |
| 10 |
26529275 | Inhibition of Polyamine Uptake Potentiates the Anti-Proliferative Effect of Polyamine Synthesis Inhibition and Preserves the Contractile Phenotype of Vascular Smooth Muscle Cells. | 2016 Jun |
2 |
| 11 |
26663722 | Targeting Ornithine Decarboxylase by α-Difluoromethylornithine Inhibits Tumor Growth by Impairing Myeloid-Derived Suppressor Cells. | 2016 Jan 15 |
6 |
| 12 |
27293987 | Simultaneous targeting of 5-LOX-COX and ODC block NNK-induced lung adenoma progression to adenocarcinoma in A/J mice. | 2016 |
1 |
| 13 |
26112945 | Effect of polyamine metabolism inhibitors on Lewis lung carcinoma growth and metastasis. | 2015 Jun |
2 |
| 14 |
26426536 | Ornithine Decarboxylase Activity Is Required for Prostatic Budding in the Developing Mouse Prostate. | 2015 |
2 |
| 15 |
23846959 | Protective effects of polyamine depletion in mouse models of type 1 diabetes: implications for therapy. | 2014 Mar |
1 |
| 16 |
24305501 | Combined administration of testosterone plus an ornithine decarboxylase inhibitor as a selective prostate-sparing anabolic therapy. | 2014 Apr |
2 |
| 17 |
24778323 | Polyamine-blocking therapy reverses immunosuppression in the tumor microenvironment. | 2014 Mar |
1 |
| 18 |
25248858 | Eflornithine (DFMO) prevents progression of pancreatic cancer by modulating ornithine decarboxylase signaling. | 2014 Dec |
7 |
| 19 |
23300995 | Critical roles of Myc-ODC axis in the cellular transformation induced by myeloproliferative neoplasm-associated JAK2 V617F mutant. | 2013 |
4 |
| 20 |
24260338 | Inhibiting cycloxygenase and ornithine decarboxylase by diclofenac and alpha-difluoromethylornithine blocks cutaneous SCCs by targeting Akt-ERK axis. | 2013 |
3 |
| 21 |
21809076 | Polyamine metabolism is involved in adipogenesis of 3T3-L1 cells. | 2012 Feb |
4 |
| 22 |
23123718 | [Analysis of oncogenic signaling pathway induced by a myeloproliferative neoplasm-associated Janus kinase 2 (JAK2) V617F mutant]. | 2012 |
2 |
| 23 |
23181218 | Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma. | 2012 |
2 |
| 24 |
20844550 | Elevated epidermal ornithine decarboxylase activity suppresses contact hypersensitivity. | 2011 Jan |
2 |
| 25 |
21237263 | LPS-induced CCL2 expression and macrophage influx into the murine central nervous system is polyamine-dependent. | 2011 May |
1 |
| 26 |
21464038 | Phospho-sulindac (OXT-328) combined with difluoromethylornithine prevents colon cancer in mice. | 2011 Jul |
4 |
| 27 |
21505150 | Ornithine decarboxylase is upregulated by the androgen receptor in skeletal muscle and regulates myoblast proliferation. | 2011 Jul |
1 |
| 28 |
21730362 | A prolonged and exaggerated wound response with elevated ODC activity mimics early tumor development. | 2011 Sep |
1 |
| 29 |
20600019 | Polyamines Impair Immunity to Helicobacter pylori by Inhibiting L-Arginine Uptake Required for Nitric Oxide Production. | 2010 Nov |
1 |
| 30 |
19001365 | Spermine synthase deficiency leads to deafness and a profound sensitivity to alpha-difluoromethylornithine. | 2009 Jan 9 |
2 |
| 31 |
19147568 | Targeting ornithine decarboxylase impairs development of MYCN-amplified neuroblastoma. | 2009 Jan 15 |
2 |
| 32 |
19427401 | Identification of proteins whose synthesis is preferentially enhanced by polyamines at the level of translation in mammalian cells. | 2009 Nov |
1 |
| 33 |
20095973 | Polyamines as mediators of APC-dependent intestinal carcinogenesis and cancer chemoprevention. | 2009 Nov 4 |
4 |
| 34 |
18202119 | Polyamines are essential in embryo implantation: expression and function of polyamine-related genes in mouse uterus during peri-implantation period. | 2008 May |
2 |
| 35 |
18381427 | Elevated ornithine decarboxylase levels activate ataxia telangiectasia mutated-DNA damage signaling in normal keratinocytes. | 2008 Apr 1 |
1 |
| 36 |
18583422 | Molecular and morphological changes in placenta and embryo development associated with the inhibition of polyamine synthesis during midpregnancy in mice. | 2008 Oct |
2 |
| 37 |
19047152 | ODC1 is a critical determinant of MYCN oncogenesis and a therapeutic target in neuroblastoma. | 2008 Dec 1 |
2 |
| 38 |
17148758 | Sexual dimorphism of ornithine decarboxylase in the mouse adrenal: influence of polyamine deprivation on catecholamine and corticoid levels. | 2007 Apr |
1 |
| 39 |
17675337 | Studies of the mechanism by which increased spermidine/spermine N1-acetyltransferase activity increases susceptibility to skin carcinogenesis. | 2007 Nov |
1 |
| 40 |
16678846 | Involvement of polyamines in apoptosis of cardiac myoblasts in a model of simulated ischemia. | 2006 Jun |
2 |
| 41 |
15514084 | Influence of ovarian ornithine decarboxylase in folliculogenesis and luteinization. | 2005 Feb |
2 |
| 42 |
15611981 | Polyamines modulate carcinogen-induced mutagenesis in vivo. | 2005 |
2 |
| 43 |
15695401 | Induction of ornithine decarboxylase activity is a necessary step for mitogen-activated protein kinase kinase-induced skin tumorigenesis. | 2005 Jan 15 |
2 |
| 44 |
15894264 | Targeting ornithine decarboxylase in Myc-induced lymphomagenesis prevents tumor formation. | 2005 May |
3 |
| 45 |
16138831 | Polyamines are involved in murine kidney development controlling expression of c-ret, E-cadherin, and Pax2/8 genes. | 2005 Jul |
1 |
| 46 |
15067319 | Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/- mice. | 2004 Mar |
1 |
| 47 |
15175104 | Therapy of murine squamous cell carcinomas with 2-difluoromethylornithine. | 2004 Jun 2 |
3 |
| 48 |
15265947 | Protective role of arginase in a mouse model of colitis. | 2004 Aug 1 |
1 |
| 49 |
12771040 | Celecoxib and difluoromethylornithine in combination have strong therapeutic activity against UV-induced skin tumors in mice. | 2003 May |
3 |
| 50 |
12856719 | Effects of alpha-difluoromethylornithine on local recurrence and pulmonary metastasis from MDA-MB-435 breast cancer xenografts in nude mice. | 2003 |
4 |