Imatinib Mesylate

phosphoglycolate phosphatase ; Homo sapiens







18 Article(s)
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1 35149540 Estimation of Fetal-to-Maternal Unbound Steady-State Plasma Concentration Ratio of P-Glycoprotein and/or Breast Cancer Resistance Protein Substrate Drugs Using a Maternal-Fetal Physiologically Based Pharmacokinetic Model. 2022 May 2
2 28238945 Nose-to-brain transport of imatinib mesylate: A pharmacokinetic evaluation. 2017 May 1 2
3 25575688 Drug transporters play a key role in the complex process of Imatinib resistance in vitro. 2015 Mar 2
4 25916699 Celecoxib sensitizes imatinib-resistant K562 cells to imatinib by inhibiting MRP1-5, ABCA2 and ABCG2 transporters via Wnt and Ras signaling pathways. 2015 Jul 1
5 24844604 Large-scale imatinib dose-concentration-effect study in CML patients under routine care conditions. 2014 Jul 1
6 24210993 Phosphorylated Crkl reduction levels are associated with the lowest P-glycoprotein activity levels in cells from chronic myeloid leukemia patients. 2013 Dec 7
7 22098951 Overexpression of P-glycoprotein induces acquired resistance to imatinib in chronic myelogenous leukemia cells. 2012 Feb 3
8 23230732 [Multidrug resistant gene MDR1 contributes to development of imatinib-resistance in Ph (+) acute lymphoblastic leukemia cell line SUP-BS15RI]. 2012 Sep 1
9 21418741 Simultaneous targeting of P-gp and XIAP with siRNAs increases sensitivity of P-gp overexpressing CML cells to imatinib. 2011 Mar 6
10 20701289 A new intestinal cell culture model to discriminate the relative contribution of P-gp and BCRP on transport of substrates such as imatinib. 2010 Oct 4 4
11 18977528 Imatinib resistance in multidrug-resistant K562 human leukemic cells. 2009 May 5
12 19309222 Imatinib is a substrate for various multidrug resistance proteins. 2009 3
13 17180388 The effect of hydroxyurea on P-glycoprotein/BCRP-mediated transport and CYP3A metabolism of imatinib mesylate. 2007 May 2
14 17294720 [Establishment of an imatinib resistance cell line K562R and its resistant principia]. 2007 Jan 1
15 16001089 Loss of P-glycoprotein expression in hematopoietic stem cells does not improve responses to imatinib in a murine model of chronic myelogenous leukemia. 2005 Sep 1
16 16320588 [Effect of neferine on the chemotherapic sensitivity of STI 571 to K562/A02 cells]. 2005 Oct 1
17 15250677 Use and limitations of imatinib mesylate (Glivec), a selective inhibitor of the tyrosine kinase Abl transcript in the treatment of chronic myeloid leukaemia. 2004 1
18 15308010 [Establishment of an imatinib resistant cell line K562/G01 and its characterization]. 2004 Jun 1