22 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 33571819 | Leflunomide an immunomodulator with antineoplastic and antiviral potentials but drug-induced liver injury: A comprehensive review. | 2021 Apr | 1 |
2 | 33610916 | Inhibition of mitochondrial complex III induces differentiation in acute myeloid leukemia. | 2021 Apr 2 | 1 |
3 | 33716051 | Effective deploying of a novel DHODH inhibitor against herpes simplex type 1 and type 2 replication. | 2021 May | 1 |
4 | 33981038 | DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer. | 2021 May | 2 |
5 | 34111397 | Efficacy and safety of dihydroorotate dehydrogenase (DHODH) inhibitors "leflunomide" and "teriflunomide" in Covid-19: A narrative review. | 2021 Sep 5 | 1 |
6 | 34442810 | The New Generation hDHODH Inhibitor MEDS433 Hinders the In Vitro Replication of SARS-CoV-2 and Other Human Coronaviruses. | 2021 Aug 14 | 2 |
7 | 34730931 | Identification of Dihydroorotate Dehydrogenase Inhibitors─Indoluidins─That Inhibit Cancer Cell Growth. | 2021 Nov 19 | 2 |
8 | 29632820 | Crystal structures of FMN-bound and FMN-free forms of dihydroorotate dehydrogenase from Trypanosoma brucei. | 2018 Apr | 1 |
9 | 29939742 | Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors. | 2018 Jul 26 | 1 |
10 | 30459406 | Novel AR-12 derivatives, P12-23 and P12-34, inhibit flavivirus replication by blocking host de novo pyrimidine biosynthesis. | 2018 Nov 21 | 1 |
11 | 28118956 | Design and synthesis of potent substrate-based inhibitors of the Trypanosoma cruzi dihydroorotate dehydrogenase. | 2017 Feb 15 | 2 |
12 | 27906623 | Orotate (orotic acid): An essential and versatile molecule. | 2016 Dec | 2 |
13 | 26059769 | Orotic Acid, More Than Just an Intermediate of Pyrimidine de novo Synthesis. | 2015 May 20 | 1 |
14 | 22242798 | CoMFA and CoMSIA studies on aryl carboxylic acid amide derivatives as dihydroorotate dehydrogenase (DHODH) inhibitors. | 2012 Dec 1 | 1 |
15 | 21436031 | Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis. | 2011 Apr 5 | 1 |
16 | 17369345 | Functional expression of human dihydroorotate dehydrogenase (DHODH) in pyr4 mutants of ustilago maydis allows target validation of DHODH inhibitors in vivo. | 2007 May | 1 |
17 | 12189151 | Malarial dihydroorotate dehydrogenase. Substrate and inhibitor specificity. | 2002 Nov 1 | 1 |
18 | 16120318 | Mechanism of leflunomide-induced proliferation of mitochondria in mammalian cells. | 2002 Dec | 1 |
19 | 11329288 | Multiple inhibitor analysis of the brequinar and leflunomide binding sites on human dihydroorotate dehydrogenase. | 2001 Feb 20 | 2 |
20 | 10889450 | Indirect inhibition of mitochondrial dihydroorotate dehydrogenase activity by nitric oxide. | 2000 Apr 15 | 2 |
21 | 2306795 | Phase I study of Brequinar sodium (NSC 368390) in patients with solid malignancies. | 1990 | 1 |
22 | 2847745 | Structure-activity relationships of pyrimidines as dihydroorotate dehydrogenase inhibitors. | 1988 Oct 15 | 1 |