Fatty Acids, Unsaturated

stearoyl-CoA desaturase ; Homo sapiens







54 Article(s)
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1 34997498 The dysregulation of unsaturated fatty acid-based metabolomics in the MNNG-induced malignant transformation of Het-1A cells. 2022 Apr 2
2 35276817 Association between FADS Gene Expression and Polyunsaturated Fatty Acids in Breast Milk. 2022 Jan 20 1
3 34059134 Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches. 2021 May 31 1
4 34199164 The Hypoxic Microenvironment Induces Stearoyl-CoA Desaturase-1 Overexpression and Lipidomic Profile Changes in Clear Cell Renal Cell Carcinoma. 2021 Jun 13 2
5 31678511 Trichothecin inhibits invasion and metastasis of colon carcinoma associating with SCD-1-mediated metabolite alteration. 2020 Feb 1
6 31943072 Influence of fatty acid desaturase (FADS) genotype on maternal and child polyunsaturated fatty acids (PUFA) status and child health outcomes: a systematic review. 2020 Aug 1 4
7 32452400 Region-specific changes in the mRNA and protein expression of LCPUFA biosynthesis enzymes and transporters in the placentae of women with preeclampsia. 2020 Jun 1
8 32778150 Postprandial effects of a meal low in sulfur amino acids and high in polyunsaturated fatty acids compared to a meal high in sulfur amino acids and saturated fatty acids on stearoyl CoA-desaturase indices and plasma sulfur amino acids: a pilot study. 2020 Aug 10 2
9 29675558 Dietary polyunsaturated fatty acids mediate the inverse association of stearoyl-CoA desaturase activity with the risk of fatty liver in dyslipidaemic individuals. 2019 Jun 3
10 30511301 Dietary pattern regulates fatty acid desaturase 1 gene expression in Indian pregnant women to spare overall long chain polyunsaturated fatty acids levels. 2019 Feb 2
11 31139819 Identification and characterization of stearoyl-CoA desaturase in Toxoplasma gondii. 2019 Jun 20 1
12 31455761 Altered polyunsaturated fatty acid levels in relation to proinflammatory cytokines, fatty acid desaturase genotype, and diet in bipolar disorder. 2019 Aug 27 1
13 29605251 Protein engineering: Regulatory perspectives of stearoyl CoA desaturase. 2018 Jul 15 2
14 29615666 Insensitivity to atorvastatin is associated with increased accumulation of intracellular lipid droplets and fatty acid metabolism in breast cancer cells. 2018 Apr 3 2
15 29636834 Allele-specific methylation in the FADS genomic region in DNA from human saliva, CD4+ cells, and total leukocytes. 2018 6
16 29869888 Discovery of Cytochrome P450 4F11 Activated Inhibitors of Stearoyl Coenzyme A Desaturase. 2018 Jun 28 2
17 30050886 Association of Polymorphism in Fatty Acid Desaturase Gene with the Risk of Type 2 Diabetes in Iranian Population. 2018 2
18 30118512 Stearoly-CoA desaturase 1 differentiates early and advanced dengue virus infections and determines virus particle infectivity. 2018 Aug 2
19 30157936 FADS1-FADS2 genetic polymorphisms are associated with fatty acid metabolism through changes in DNA methylation and gene expression. 2018 Aug 29 2
20 28555039 FADS Gene Polymorphisms, Fatty Acid Desaturase Activities, and HDL-C in Type 2 Diabetes. 2017 May 28 2
21 28579896 The cytoprotective effects of Δ-17 fatty acid desaturase on injured HUVECs and its underlying mechanism. 2017 May 2
22 26912491 Maternal single nucleotide polymorphisms in the fatty acid desaturase 1 and 2 coding regions modify the impact of prenatal supplementation with DHA on birth weight. 2016 Apr 4
23 27042297 Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments. 2016 2
24 27197070 Impact of Genetic and Epigenetic Variations Within the FADS Cluster on the Composition and Metabolism of Polyunsaturated Fatty Acids in Prostate Cancer. 2016 Sep 1
25 27223066 SCD1 is associated with tumor promotion, late stage and poor survival in lung adenocarcinoma. 2016 Jun 28 2
26 27269715 Association of polyunsaturated fatty acids in breast milk with fatty acid desaturase gene polymorphisms among Chinese lactating mothers. 2016 Jun 5
27 25646338 Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. 2015 Feb 1
28 25264165 Binding of polyunsaturated fatty acids to LXRα and modulation of SREBP-1 interaction with a specific SCD1 promoter element. 2014 Dec 3
29 23404690 Plasma stearoyl-CoA desaturase indices: association with lifestyle, diet, and body composition. 2013 Mar 2
30 23512934 Associations between plasma polyunsaturated fatty acids, plasma stearoyl-CoA desaturase indices and body fat. 2013 Sep 1
31 24075244 Dietary arachidonic acid and docosahexaenoic acid regulate liver fatty acid desaturase (FADS) alternative transcript expression in suckling piglets. 2013 Oct 1
32 22194195 Polyunsaturated fatty acid levels in blood during pregnancy, at birth and at 7 years: their associations with two common FADS2 polymorphisms. 2012 Apr 1 2
33 22803604 Nutritional aspects of epigenetic inheritance. 2012 Aug 2
34 20648548 Selective regulation of UGT1A1 and SREBP-1c mRNA expression by docosahexaenoic, eicosapentaenoic, and arachidonic acids. 2011 Jan 2
35 20713121 Hormonal and nutritional regulation of SCD1 gene expression. 2011 Jan 1
36 21366865 Genetic variation in polyunsaturated fatty acid metabolism and its potential relevance for human development and health. 2011 Apr 1
37 21513558 Fatty acid desaturase (FADS) gene polymorphisms and insulin resistance in association with serum phospholipid polyunsaturated fatty acid composition in healthy Korean men: cross-sectional study. 2011 Apr 23 4
38 21954435 Cancer cell dependence on unsaturated fatty acids implicates stearoyl-CoA desaturase as a target for cancer therapy. 2011 Nov 3
39 20489212 Decrease in membrane phospholipid unsaturation induces unfolded protein response. 2010 Jul 16 2
40 21291825 Regulation of human stearoyl-CoA desaturase by omega-3 and omega-6 fatty acids: Implications for the dietary management of elevated serum triglycerides. 2009 Aug 2
41 15855323 Rosiglitazone increases indexes of stearoyl-CoA desaturase activity in humans: link to insulin sensitization and the role of dominant-negative mutation in peroxisome proliferator-activated receptor-gamma. 2005 May 2
42 14967823 LXR-mediated activation of macrophage stearoyl-CoA desaturase generates unsaturated fatty acids that destabilize ABCA1. 2004 May 1
43 15556291 Isolation and molecular characterization of the porcine stearoyl-CoA desaturase gene. 2004 Sep 29 4
44 11677241 Transforming growth factor-beta regulates stearoyl coenzyme A desaturase expression through a Smad signaling pathway. 2002 Jan 4 4
45 11397803 Regulation of stearoyl coenzyme A desaturase expression in human retinal pigment epithelial cells by retinoic acid. 2001 Aug 3 1
46 11414710 Cloning and characterization of the human stearoyl-CoA desaturase gene promoter: transcriptional activation by sterol regulatory element binding protein and repression by polyunsaturated fatty acids and cholesterol. 2001 Jun 29 3
47 11415448 Isolation and characterization of the human stearoyl-CoA desaturase gene promoter: requirement of a conserved CCAAT cis-element. 2001 Jul 1 1
48 10229681 Human stearoyl-CoA desaturase: alternative transcripts generated from a single gene by usage of tandem polyadenylation sites. 1999 May 15 2
49 9867800 Glucose induces expression of stearoyl-CoA desaturase in 3T3-L1 adipocytes. 1998 Oct 15 2
50 9421194 Localization of a polyunsaturated fatty acid response region in stearoyl-CoA desaturase gene 1. 1997 Nov 8 2