Fatty Acids, Monounsaturated

stearoyl-CoA desaturase ; Homo sapiens







116 Article(s)
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1 32954972 Maternal hypercaloric diet affects factors involved in lipid metabolism and the endogenous cannabinoid systems in the hypothalamus of adult offspring: sex-specific response of astrocytes to palmitic acid and anandamide. 2022 May 1
2 33829984 Polymorphisms in the stearoyl-CoA desaturase gene modify blood glucose response to dietary oils varying in MUFA content in adults with obesity. 2022 Feb 28 1
3 35126846 Stearoyl-CoA desaturase 1: A potential target for non-alcoholic fatty liver disease?-perspective on emerging experimental evidence. 2022 Jan 27 2
4 33049404 Stearoyl-CoA desaturase 5 (SCD5), a Δ-9 fatty acyl desaturase in search of a function. 2021 Jan 3
5 33218679 Lipid metabolism in colon cancer: Role of Liver X Receptor (LXR) and Stearoyl-CoA Desaturase 1 (SCD1). 2021 Apr 2
6 33406440 Stearoyl-CoA Desaturase-Mediated Monounsaturated Fatty Acid Availability Supports Humoral Immunity. 2021 Jan 5 1
7 33612070 NF-κB pathway play a role in SCD1 deficiency-induced ceramide de novo synthesis. 2021 Feb 1 2
8 33868572 Stearoyl-CoA Desaturase 1 Potentiates Hypoxic plus Nutrient-Deprived Pancreatic Cancer Cell Ferroptosis Resistance. 2021 4
9 33954906 Modulation of SCD1 activity in hepatocyte cell lines: evaluation of genomic stability and proliferation. 2021 Sep 4
10 34171462 Polymorphisms rs55710213 and rs56334587 regulate SCD1 expression by modulating HNF4A binding. 2021 Aug 6
11 34293334 Nicotinamide phosphoribosyltransferase inhibitors selectively induce apoptosis of AML stem cells by disrupting lipid homeostasis. 2021 Oct 7 2
12 34429143 SCD1, autophagy and cancer: implications for therapy. 2021 Aug 24 2
13 34486791 Increased lipogenesis is critical for self-renewal and growth of breast cancer stem cells: Impact of omega-3 fatty acids. 2021 Dec 4
14 34564414 Lipidomic Analysis of Archival Pathology Specimens Identifies Altered Lipid Signatures in Ovarian Clear Cell Carcinoma. 2021 Sep 3 1
15 31838050 Stearoyl-CoA desaturase and tumorigenesis. 2020 Jan 25 5
16 31936134 Sterculic Acid: The Mechanisms of Action beyond Stearoyl-CoA Desaturase Inhibition and Therapeutic Opportunities in Human Diseases. 2020 Jan 7 4
17 32097464 Stearoyl-CoA desaturase-1 impairs the reparative properties of macrophages and microglia in the brain. 2020 May 4 1
18 32133634 Inhibition of stearoyl-CoA desaturases suppresses follicular help T- and germinal center B- cell responses. 2020 Jul 4
19 32315834 Structure-based virtual screening of natural products as potential stearoyl-coenzyme a desaturase 1 (SCD1) inhibitors. 2020 Jun 4
20 32567273 [Effects of SCD-1 gene overexpression on the content of calcium ion and lipids in duck uterine epithelial cells]. 2020 May 25 2
21 32726752 Stearoyl-CoA desaturase 1 (SCD1) facilitates the growth and anti-ferroptosis of gastric cancer cells and predicts poor prognosis of gastric cancer. 2020 Jul 29 4
22 32952654 Y-box binding protein 1 acts as a negative regulator of stearoyl CoA desaturase 1 in clear cell renal cell carcinoma. 2020 Nov 4
23 32967957 Inositol-Requiring Enzyme 1α Promotes Zika Virus Infection through Regulation of Stearoyl Coenzyme A Desaturase 1-Mediated Lipid Metabolism. 2020 Nov 9 3
24 33041516 Reduction of stearoyl-CoA desaturase (SCD) contributes muscle atrophy through the excess endoplasmic reticulum stress in chronic kidney disease. 2020 Sep 1
25 33229547 Oncogenic activation of PI3K-AKT-mTOR signaling suppresses ferroptosis via SREBP-mediated lipogenesis. 2020 Dec 8 2
26 30650256 A Phase 1 Randomized, Placebo-Controlled Trial With a Topical Inhibitor of Stearoyl-Coenzyme A Desaturase 1 Under Occluded and Nonoccluded Conditions. 2019 Apr 2
27 30790642 Modulating Wnt signaling at the root: Porcupine and Wnt acylation. 2019 Jun 1
28 31019378 SCD1 is required for EGFR-targeting cancer therapy of lung cancer via re-activation of EGFR/PI3K/AKT signals. 2019 1
29 31199678 Sorafenib kills liver cancer cells by disrupting SCD1-mediated synthesis of monounsaturated fatty acids via the ATP-AMPK-mTOR-SREBP1 signaling pathway. 2019 Sep 3
30 31270077 Stearoyl-CoA Desaturase 1 Protects Ovarian Cancer Cells from Ferroptotic Cell Death. 2019 Oct 15 1
31 31481234 Clinical and biochemical relevance of monounsaturated fatty acid metabolism targeting strategy for cancer stem cell elimination in colon cancer. 2019 Oct 29 5
32 31592021 Novel Lipid Long Intervening Noncoding RNA, Oligodendrocyte Maturation-Associated Long Intergenic Noncoding RNA, Regulates the Liver Steatosis Gene Stearoyl-Coenzyme A Desaturase As an Enhancer RNA. 2019 Oct 1
33 31708874 Induction of Stearoyl-CoA 9-Desaturase 1 Protects Human Mesenchymal Stromal Cells Against Palmitic Acid-Induced Lipotoxicity and Inflammation. 2019 2
34 29524401 Ablation of prolactin receptor increases hepatic triglyceride accumulation. 2018 Apr 6 2
35 29530061 Stearoyl-CoA desaturase-1 promotes colorectal cancer metastasis in response to glucose by suppressing PTEN. 2018 Mar 12 4
36 29605251 Protein engineering: Regulatory perspectives of stearoyl CoA desaturase. 2018 Jul 15 2
37 30118512 Stearoly-CoA desaturase 1 differentiates early and advanced dengue virus infections and determines virus particle infectivity. 2018 Aug 1
38 30317781 [Research progress of stearoyl-CoA desaturase-1 on obesity and non-alcoholic fatty liver disease Abstract]. 2018 Jul 20 2
39 30457128 Potential contribution of monounsaturated fatty acids to cardiovascular risk in chronic kidney disease. 2018 Dec 21 2
40 30656903 The role of stearoyl-CoA desaturase in the regulation of cardiac metabolism. 2018 Oct 25 2
41 27881438 Ole1, fatty acid desaturase, is required for Atg9 delivery and isolation membrane expansion during autophagy in Saccharomyces cerevisiae. 2017 Jan 15 4
42 28145413 Stearoyl-CoA desaturase-1, a novel target of omega-3 fatty acids for reducing breast cancer risk in obese postmenopausal women. 2017 Jun 2
43 28286737 PDGF-induced fibroblast growth requires monounsaturated fatty acid production by stearoyl-CoA desaturase. 2017 Mar 1
44 28368399 Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ. 2017 Aug 10 2
45 28724430 EGFR modulates monounsaturated fatty acid synthesis through phosphorylation of SCD1 in lung cancer. 2017 Jul 19 1
46 28768997 Loss of Stearoyl-CoA Desaturase-1 Activity Induced Leptin Resistance in Neuronal Cells. 2017 1
47 28797843 Blockade of Stearoyl-CoA-desaturase 1 activity reverts resistance to cisplatin in lung cancer stem cells. 2017 Oct 10 2
48 29089222 Insights into Stearoyl-CoA Desaturase-1 Regulation of Systemic Metabolism. 2017 Dec 2
49 29354058 SCD1 Confers Temozolomide Resistance to Human Glioma Cells via the Akt/GSK3β/β-Catenin Signaling Axis. 2017 2
50 26344107 Recent progress in the discovery and development of stearoyl CoA desaturase inhibitors. 2016 May 2