Dinoprostone

prostaglandin-endoperoxide synthase 2 ; Mus musculus







390 Article(s)
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151 23390011 Targeting the EP1 receptor reduces Fas ligand expression and increases the antitumor immune response in an in vivo model of colon cancer. 2013 Aug 15 4
152 23632967 Prostaglandin E2 type 1 receptors contribute to neuronal apoptosis after transient forebrain ischemia. 2013 Aug 2
153 23639875 Prostaglandin E2 acts via bone marrow macrophages to block PTH-stimulated osteoblast differentiation in vitro. 2013 Sep 5
154 23741059 Epithelial-specific deletion of 11β-HSD2 hinders Apcmin/+ mouse tumorigenesis. 2013 Sep 4
155 23814491 Prostaglandin E2 Promotes UV radiation-induced immune suppression through DNA hypermethylation. 2013 Jul 2
156 23851295 Calcium-mediated increased expression of fibroblast growth factor-2 acts through NF-κB and PGE2/EP4 receptor signaling pathways in cementoblasts. 2013 Oct 2
157 23893854 CCAAT/enhancer binding protein β regulates prostaglandin E synthase expression and prostaglandin E2 production in activated microglial cells. 2013 Oct 4
158 23922381 Coordinated induction of cyclooxygenase-2/prostaglandin E2 and hepatocyte growth factor by apoptotic cells prevents lung fibrosis. 2013 Nov 1
159 23943621 Coordinate functional regulation between microsomal prostaglandin E synthase-1 (mPGES-1) and peroxisome proliferator-activated receptor γ (PPARγ) in the conversion of white-to-brown adipocytes. 2013 Sep 27 1
160 24018272 Induction of cyclooxygenase-2 signaling by Stomatococcus mucilaginosus highlights the pathogenic potential of an oral commensal. 2013 Oct 1 2
161 24126890 Low doses of celecoxib attenuate gut barrier failure during experimental peritonitis. 2013 Dec 3
162 24376609 Bisgma stimulates prostaglandin E2 production in macrophages via cyclooxygenase-2, cytosolic phospholipase A2, and mitogen-activated protein kinases family. 2013 1
163 21761157 Frondoside A inhibits breast cancer metastasis and antagonizes prostaglandin E receptors EP4 and EP2. 2012 Apr 1
164 22082586 β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells. 2012 Sep 2
165 22294551 N-Acetylglucosaminyltransferase V regulates TGF-β response in hepatic stellate cells and the progression of steatohepatitis. 2012 Jun 3
166 22353212 1-Bromopropane up-regulates cyclooxygenase-2 expression via NF-κB and C/EBP activation in murine macrophages. 2012 May 2
167 22493349 5-aminosalicylic acid mediates expression of cyclooxygenase-2 and 15-hydroxyprostaglandin dehydrogenase to suppress colorectal tumorigenesis. 2012 Apr 4
168 22573380 Temporal expression of the PGE2 synthetic system in the kidney is associated with the time frame of renal developmental vulnerability to cyclooxygenase-2 inhibition. 2012 Jul 15 3
169 22728095 Saikosaponin a and its epimer saikosaponin d exhibit anti-inflammatory activity by suppressing activation of NF-κB signaling pathway. 2012 Sep 1
170 22747786 c-Src-dependent EGF receptor transactivation contributes to ET-1-induced COX-2 expression in brain microvascular endothelial cells. 2012 Jul 2 2
171 22759265 Inflammation modulates expression of laminin in the central nervous system following ischemic injury. 2012 Jul 3 2
172 22872578 Lipopolysaccharide-induced fever depends on prostaglandin E2 production specifically in brain endothelial cells. 2012 Oct 1
173 22964849 Stimulation of fat accumulation in hepatocytes by PGE₂-dependent repression of hepatic lipolysis, β-oxidation and VLDL-synthesis. 2012 Nov 1
174 22970288 Synergistic suppression of early phase of adipogenesis by microsomal PGE synthase-1 (PTGES1)-produced PGE2 and aldo-keto reductase 1B3-produced PGF2α. 2012 3
175 23040893 Synthesis of 1,5-diarylhaloimidazole analogs and their inhibitory activities against PGE₂ production from LPS-treated RAW 264.7 cells. 2012 Nov 1 1
176 23041393 Kidney proximal tubular epithelial-specific overexpression of netrin-1 suppresses inflammation and albuminuria through suppression of COX-2-mediated PGE2 production in streptozotocin-induced diabetic mice. 2012 Dec 1
177 20854947 Constitutively expressed COX-2 in osteoblasts positively regulates Akt signal transduction via suppression of PTEN activity. 2011 Feb 2
178 20939055 EP1(-/-) mice have enhanced osteoblast differentiation and accelerated fracture repair. 2011 Apr 4
179 21070778 Prostaglandin E₂ signaling and bacterial infection recruit tumor-promoting macrophages to mouse gastric tumors. 2011 Feb 4
180 21075851 Anti-inflammatory role of microsomal prostaglandin E synthase-1 in a model of neuroinflammation. 2011 Jan 21 2
181 21205091 Activation of epidermal growth factor receptor signaling by the prostaglandin E(2) receptor EP4 pathway during gastric tumorigenesis. 2011 Apr 4
182 21225228 Honokiol, a phytochemical from Magnolia spp., inhibits breast cancer cell migration by targeting nitric oxide and cyclooxygenase-2. 2011 Mar 1
183 21291962 Effects of chelerythrine, a specific inhibitor of cyclooxygenase-2, on acute inflammation in mice. 2011 Jun 1
184 21391980 Defects in mouse nephrogenesis induced by selective and non-selective cyclooxygenase-2 inhibitors. 2011 Jul 1
185 21553651 PDE4 inhibitor suppresses PGE2-induced osteoclast formation via COX-2-mediated p27(KIP1) expression in RAW264.7 cells. 2011 Mar 4
186 21719163 A chrysin analog exhibited strong inhibitory activities against both PGE2 and NO production. 2011 Sep 1
187 21835766 A major role for the EP4 receptor in regulation of renin. 2011 Nov 1
188 21946106 New synthetic anti-inflammatory chrysin analog, 5,7-dihydroxy-8-(pyridine-4yl)flavone. 2011 Nov 30 3
189 21957141 Hydrogen sulfide upregulates cyclooxygenase-2 and prostaglandin E metabolite in sepsis-evoked acute lung injury via transient receptor potential vanilloid type 1 channel activation. 2011 Nov 1 2
190 24212947 Toll-like receptor 4 signaling integrates intestinal inflammation with tumorigenesis: lessons from the murine model of colitis-associated cancer. 2011 Aug 2 4
191 19857488 Anti-inflammatory activity of hispidol A 25-methyl ether, a triterpenoid isolated from Ponciri Immaturus Fructus. 2010 Feb 10 4
192 19897661 PGE2 receptor EP2 mediates the antagonistic effect of COX-2 on TGF-beta signaling during mammary tumorigenesis. 2010 Apr 2
193 19914295 Striatal 6-OHDA lesion in mice: Investigating early neurochemical changes underlying Parkinson's disease. 2010 Mar 17 1
194 19926832 Absence of myeloid COX-2 attenuates acute inflammation but does not influence development of atherosclerosis in apolipoprotein E null mice. 2010 Feb 1
195 20025057 Expression of cyclooxygenase-2 and microsomal prostaglandin-E synthase in amoeboid microglial cells in the developing brain and effects of cyclooxygenase-2 neutralization on BV-2 microglial cells. 2010 May 15 1
196 20034447 Inhibitory effect of Angelicae Tenuissimae Radix on expressions of cyclooxygenase-2 and inducible nitric oxide synthase in mouse BV2 microglial cells. 2010 Feb 1
197 20147609 Lymphocyte responses exacerbate angiotensin II-dependent hypertension. 2010 Apr 1
198 20435922 Resolution of inflammation in murine autoimmune arthritis is disrupted by cyclooxygenase-2 inhibition and restored by prostaglandin E2-mediated lipoxin A4 production. 2010 Jun 1 2
199 20671216 A maladaptive role for EP4 receptors in podocytes. 2010 Oct 1
200 20874228 An extract of Phellinus linteus grown on germinated brown rice inhibits inflammation markers in RAW264.7 macrophages by suppressing inflammatory cytokines, chemokines, and mediators and up-regulating antioxidant activity. 2010 Dec 1