Tetradecanoylphorbol Acetate

prostaglandin-endoperoxide synthase 2 ; Mus musculus







94 Article(s)
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1 33310310 3'-Hydroxypterostilbene Inhibits 7,12-Dimethylbenz[a]anthracene (DMBA)/12-O-Tetradecanoylphorbol-13-Acetate (TPA)-Induced Mouse Skin Carcinogenesis. 2021 Jan 2
2 29423390 Dual Effects of High Protein Diet on Mouse Skin and Colonic Inflammation. 2018 Jan 2
3 29458014 Topical delivery of l-theanine ameliorates TPA-induced acute skin inflammation via downregulating endothelial PECAM-1 and neutrophil infiltration and activation. 2018 Mar 25 2
4 30288224 Glycyrrhizic acid from licorice down-regulates inflammatory responses via blocking MAPK and PI3K/Akt-dependent NF-κB signalling pathways in TPA-induced skin inflammation. 2018 Sep 1 2
5 26848699 Role of the Slug Transcription Factor in Chemically-Induced Skin Cancer. 2016 Feb 3 2
6 26950613 Heme oxygenase-1-mediated anti-inflammatory effects of tussilagonone on macrophages and 12-O-tetradecanoylphorbol-13-acetate-induced skin inflammation in mice. 2016 May 1
7 26345246 Potent inhibitory effect of silibinin from milk thistle on skin inflammation stimuli by 12-O-tetradecanoylphorbol-13-acetate. 2015 Dec 2
8 23983093 The preventive role of breadfruit against inflammation-associated epithelial carcinogenesis in mice. 2014 Jan 3
9 24909729 Upregulation of COX-2 in the lung cancer promotes overexpression of multidrug resistance protein 4 (MRP4) via PGE2-dependent pathway. 2014 Oct 1 2
10 25063587 Targeted deletion and lipidomic analysis identify epithelial cell COX-2 as a major driver of chemically induced skin cancer. 2014 Nov 2
11 25374129 Piceatannol inhibits phorbol ester-induced expression of COX-2 and iNOS in HR-1 hairless mouse skin by blocking the activation of NF-κB and AP-1. 2014 Dec 2
12 23457529 Altered prostanoid signaling contributes to increased skin tumorigenesis in Tpl2 knockout mice. 2013 2
13 23530644 Chemopreventive effects of the juice of Vitis coignetiae Pulliat on two-stage mouse skin carcinogenesis. 2013 2
14 23563532 Toxicological evaluation and anti-inflammatory activity of a golden gelatinous sorghum bran extract. 2013 1
15 23911786 Thymoquinone inhibits phorbol ester-induced activation of NF-κB and expression of COX-2, and induces expression of cytoprotective enzymes in mouse skin in vivo. 2013 Sep 6 5
16 22181070 Phloretin inhibits phorbol ester-induced tumor promotion and expression of cyclooxygenase-2 in mouse skin: extracellular signal-regulated kinase and nuclear factor-κB as potential targets. 2012 Mar 2
17 22318307 D-Limonene modulates inflammation, oxidative stress and Ras-ERK pathway to inhibit murine skin tumorigenesis. 2012 Aug 1
18 22542552 Piperine inhibits PMA-induced cyclooxygenase-2 expression through downregulating NF-κB, C/EBP and AP-1 signaling pathways in murine macrophages. 2012 Jul 6
19 22986104 Effects of C-Phycocyanin on the representative genes of tumor development in mouse skin exposed to 12-O-tetradecanoyl-phorbol-13-acetate. 2012 Nov 1
20 21268127 Upregulation of the EP1 receptor for prostaglandin E2 promotes skin tumor progression. 2011 Jun 1
21 21292288 A sesquiterpenol extract potently suppresses inflammation in macrophages and mice skin and prevents chronic liver damage in mice through JNK-dependent HO-1 expression. 2011 Apr 2
22 21324306 Effects of pergolide mesylate on transduction efficiency of PEP-1-catalase protein. 2011 Mar 18 1
23 21989206 Anti-inflammatory effect of transduced PEP-1-cyclophilin A in Raw264.7 cells and 12-O-tetradecanoylphorbol-13-acetate-induced mice. 2011 Dec 5 1
24 22189182 Topical application of marine briarane-type diterpenes effectively inhibits 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and dermatitis in murine skin. 2011 Dec 21 1
25 20218615 Inhibitory effect of magnolol on TPA-induced skin inflammation and tumor promotion in mice. 2010 May 12 5
26 20336681 6-Shogaol is more effective than 6-gingerol and curcumin in inhibiting 12-O-tetradecanoylphorbol 13-acetate-induced tumor promotion in mice. 2010 Sep 2
27 20660715 Cocarcinogenic effect of capsaicin involves activation of EGFR signaling but not TRPV1. 2010 Sep 1 3
28 20709134 Transduced PEP-1-ribosomal protein S3 (rpS3) ameliorates 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice. 2010 Oct 29 2
29 18848748 Inhibitory effects of oligonol on phorbol ester-induced tumor promotion and COX-2 expression in mouse skin: NF-kappaB and C/EBP as potential targets. 2009 Jan 8 3
30 19470390 Chemopreventive effect of farnesol on DMBA/TPA-induced skin tumorigenesis: involvement of inflammation, Ras-ERK pathway and apoptosis. 2009 Jul 31 1
31 19759192 IL-12 deficiency suppresses 12-O-tetradecanoylphorbol-13-acetate-induced skin tumor development in 7,12-dimethylbenz(a)anthracene-initiated mouse skin through inhibition of inflammation. 2009 Nov 1
32 18164693 Topical transduction of superoxide dismutase mediated by HIV-1 Tat protein transduction domain ameliorates 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice. 2008 Mar 15 2
33 18234971 A JNK1/AP-1-dependent, COX-2 induction is implicated in 12-O-tetradecanoylphorbol-13-acetate-induced cell transformation through regulating cell cycle progression. 2008 Jan 16
34 18400024 Polymeric black tea polyphenols inhibit mouse skin chemical carcinogenesis by decreasing cell proliferation. 2008 Jun 1
35 18534633 Hemin inhibits cyclooxygenase-2 expression through nuclear factor-kappa B activation and ornithine decarboxylase expression in 12-O-tetradecanoylphorbol-13-acetate-treated mouse skin. 2008 Jul 3 1
36 18800802 Chondroitin sulfate extracted from ascidian tunic inhibits phorbol ester-induced expression of Inflammatory factors VCAM-1 and COX-2 by blocking NF-kappaB activation in mouse skin. 2008 Oct 22 1
37 16950795 cis-9,trans-11-conjugated linoleic acid down-regulates phorbol ester-induced NF-kappaB activation and subsequent COX-2 expression in hairless mouse skin by targeting IkappaB kinase and PI3K-Akt. 2007 Feb 5
38 17143503 Effects of 6-(methylsulfinyl)hexyl isothiocyanate on cyclooxygenase-2 expression induced by lipopolysaccharide, interferon-gamma and 12-O-tetradecanoylphorbol-13-acetate. 2007 Jan 4
39 17202682 Inhibitory effects of asiatic acid on 7,12-dimethylbenz[a]anthracene and 12-O-tetradecanoylphorbol 13-acetate-induced tumor promotion in mice. 2007 Jan 2
40 17203971 Protein expression profiles in the epidermis of cyclooxygenase-2 transgenic mice by 2-dimensional gel electrophoresis and mass spectrometry. 2007 Jan 6
41 17234720 Xanthorrhizol inhibits 12-O-tetradecanoylphorbol-13-acetate-induced acute inflammation and two-stage mouse skin carcinogenesis by blocking the expression of ornithine decarboxylase, cyclooxygenase-2 and inducible nitric oxide synthase through mitogen-activated protein kinases and/or the nuclear factor-kappa B. 2007 Jun 3
42 17277233 Prostaglandin receptor EP2 is responsible for cyclooxygenase-2 induction by prostaglandin E2 in mouse skin. 2007 Oct 3
43 17372274 Humulone inhibits phorbol ester-induced COX-2 expression in mouse skin by blocking activation of NF-kappaB and AP-1: IkappaB kinase and c-Jun-N-terminal kinase as respective potential upstream targets. 2007 Jul 3
44 17404063 Epigallocatechin gallate inhibits phorbol ester-induced activation of NF-kappa B and CREB in mouse skin: role of p38 MAPK. 2007 Jan 2
45 17962218 Inhibitory effect of citrus 5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone on 12-O-tetradecanoylphorbol 13-acetate-induced skin inflammation and tumor promotion in mice. 2007 Dec 5
46 16424000 Protein kinase C delta overexpressing transgenic mice are resistant to chemically but not to UV radiation-induced development of squamous cell carcinomas: a possible link to specific cytokines and cyclooxygenase-2. 2006 Jan 15 1
47 16474181 Resveratrol inhibits phorbol ester-induced expression of COX-2 and activation of NF-kappaB in mouse skin by blocking IkappaB kinase activity. 2006 Jul 6
48 16475165 Knockdown of NFAT3 blocked TPA-induced COX-2 and iNOS expression, and enhanced cell transformation in Cl41 cells. 2006 Nov 1 2
49 16999939 Resveratrol modulates phorbol ester-induced pro-inflammatory signal transduction pathways in mouse skin in vivo: NF-kappaB and AP-1 as prime targets. 2006 Nov 30 5
50 15498788 Antitumor promotional effects of a novel intestinal bacterial metabolite (IH-901) derived from the protopanaxadiol-type ginsenosides in mouse skin. 2005 Feb 2