omapatrilat

angiotensin I converting enzyme ; Homo sapiens







32 Article(s)
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1 32195541 ACE-domain selectivity extends beyond direct interacting residues at the active site. 2020 Apr 17 1
2 30283782 Neprilysin Inhibitors and Bradykinin. 2018 1
3 30372620 Molecular Basis for Multiple Omapatrilat Binding Sites within the ACE C-Domain: Implications for Drug Design. 2018 Nov 21 2
4 28419972 Neprilysin inhibitors: A new hope to halt the diabetic cardiovascular and renal complications? 2017 Jun 3
5 26209000 Angiotensin receptor neprilysin inhibition in heart failure: mechanistic action and clinical impact. 2015 Sep 1
6 23927843 Endothelial permeability in vitro and in vivo: protective actions of ANP and omapatrilat in experimental atherosclerosis. 2013 Oct 2
7 21853869 The natriuretic peptide neurohormonal system modulation by vasopeptidase inhibitors--the novel therapeutical approach of hypertension treatment. 2009 2
8 16086927 Effect of angiotensin-converting enzyme or vasopeptidase inhibition on ventricular size and function in patients with heart failure: the Omapatrilat Versus Enalapril Randomized Trial of Utility in Reducing Events (OVERTURE) echocardiographic study. 2005 Aug 1
9 16379325 [Omapatrilat--new drug for patients with hypertension and heart failure]. 2005 Oct 1
10 14965315 The shift in the "paradigm" of the pharmacology of hypertension. 2004 1
11 14498755 Dual ACE and neutral endopeptidase inhibitors: novel therapy for patients with cardiovascular disorders. 2003 1
12 11827932 Differential actions of vasopeptidase inhibition versus angiotensin-converting enzyme inhibition on diuretic therapy in experimental congestive heart failure. 2002 Feb 5 2
13 11875587 Vasopeptidase inhibition: a novel approach to cardiovascular therapy. 2002 Feb 2
14 12045365 Omapatrilat provides long-term control of hypertension: a randomized trial of treatment withdrawal. 2002 May-Jun 1
15 12084605 Vasopeptidase inhibition with omapatrilat in chronic heart failure: acute and long-term hemodynamic and neurohumoral effects. 2002 Jun 19 3
16 12215465 Renal hemodynamic and natriuretic effects of concomitant Angiotensin-converting enzyme and neutral endopeptidase inhibition in men. 2002 Sep 1
17 12239234 Physiologic consequences of vasopeptidase inhibition in humans: effect of sodium intake. 2002 Oct 1
18 12584671 Effects of the vasopeptidase inhibitor, omapatrilat, in 723 patients with coronary heart disease. 2002 Dec 1
19 11230840 Effects of omapatrilat on systemic arterial function in patients with chronic heart failure. 2001 Mar 1 1
20 11413936 Effects of age and gender on the pharmacodynamics of omapatrilat in healthy volunteers. 2001 Jan-Feb 1
21 11564390 Effects of omapatrilat on hemodynamics and safety in patients with heart failure. 2001 Sep 15 1
22 11588409 Advances in antihypertensive combination therapy: benefits of low-dose thiazide diuretics in conjunction with omapatrilat, a vasopeptidase inhibitor. 2001 Sep-Oct 2
23 11716802 Effects of omapatrilat on pharmacodynamic biomarkers of neutral endopeptidase and Angiotensin-converting enzyme activity in humans. 2001 Dec 1
24 11751715 Omapatrilat versus lisinopril: efficacy and neurohormonal profile in salt-sensitive hypertensive patients. 2001 Dec 1 1
25 11890357 Omapatrilat. Bristol-Myers Squibb. 2001 Oct 2
26 10856268 In vitro and in vivo inhibition of the 2 active sites of ACE by omapatrilat, a vasopeptidase inhibitor. 2000 Jun 5
27 10933361 The clinical, cardiac, renal, arterial and neurohormonal effects of omapatrilat, a vasopeptidase inhibitor, in patients with chronic heart failure. 2000 Aug 1
28 10968433 Comparison of vasopeptidase inhibitor, omapatrilat, and lisinopril on exercise tolerance and morbidity in patients with heart failure: IMPRESS randomised trial. 2000 Aug 19 2
29 11014407 Disposition and safety of omapatrilat in subjects with renal impairment. 2000 Sep 1
30 11046097 Protective effect of omapatrilat, a vasopeptidase inhibitor, on the metabolism of bradykinin in normal and failing human hearts. 2000 Nov 2
31 12845340 Omapatrilat: clinical pharmacology. 2000 Dec 2
32 10340842 Vasopeptidase inhibition: a new concept in blood pressure management. 1999 Feb 1