Reactive Oxygen Species

DNA damage inducible transcript 3 ; Homo sapiens







80 Article(s)
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51 23533616 Endoplasmic reticulum stress signaling is involved in mitomycin C (MMC)-induced apoptosis in human fibroblasts via PERK pathway. 2013 2
52 23536831 Casticin potentiates TRAIL-induced apoptosis of gastric cancer cells through endoplasmic reticulum stress. 2013 3
53 23554101 The chalcone 2'-hydroxy-4',5'-dimethoxychalcone activates death receptor 5 pathway and leads to apoptosis in human nonsmall cell lung cancer cells. 2013 Jun 1
54 24078627 Azadirone, a limonoid tetranortriterpene, induces death receptors and sensitizes human cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) through a p53 protein-independent mechanism: evidence for the role of the ROS-ERK-CHOP-death receptor pathway. 2013 Nov 8 4
55 21660448 5, 7-Dimethoxyflavone sensitizes TRAIL-induced apoptosis through DR5 upregulation in hepatocellular carcinoma cells. 2012 Jan 1
56 21797841 Cardamonin sensitizes tumour cells to TRAIL through ROS- and CHOP-mediated up-regulation of death receptors and down-regulation of survival proteins. 2012 Feb 1
57 22004570 Zyflamend sensitizes tumor cells to TRAIL-induced apoptosis through up-regulation of death receptors and down-regulation of survival proteins: role of ROS-dependent CCAAT/enhancer-binding protein-homologous protein pathway. 2012 Mar 1 2
58 22281495 Reactive oxygen species-mediated endoplasmic reticulum stress contributes to aldosterone-induced apoptosis in tubular epithelial cells. 2012 Feb 17 1
59 22328338 The anti-obesity drug orlistat promotes sensitivity to TRAIL by two different pathways in hormone-refractory prostate cancer cells. 2012 May 2
60 22922338 Capsazepine, a TRPV1 antagonist, sensitizes colorectal cancer cells to apoptosis by TRAIL through ROS-JNK-CHOP-mediated upregulation of death receptors. 2012 Nov 15 8
61 21703327 Induction of CCAAT/enhancer-binding protein-homologous protein by cigarette smoke through the superoxide anion-triggered PERK-eIF2α pathway. 2011 Sep 5 1
62 21709020 PERK integrates autophagy and oxidative stress responses to promote survival during extracellular matrix detachment. 2011 Sep 1
63 22046282 Silencing GADD153/CHOP gene expression protects against Alzheimer's disease-like pathology induced by 27-hydroxycholesterol in rabbit hippocampus. 2011 3
64 20154087 Celastrol, a triterpene, enhances TRAIL-induced apoptosis through the down-regulation of cell survival proteins and up-regulation of death receptors. 2010 Apr 9 2
65 20198322 Photoactivation of 9-hydroxypheophorbide alpha triggers apoptosis through the reactive oxygen species-mediated mitochondrial pathway and endoplasmic reticulum stress in AMC-HN-3 laryngeal cancer cells. 2010 Apr 1
66 20459685 Cadmium induces Wnt signaling to upregulate proliferation and survival genes in sub-confluent kidney proximal tubule cells. 2010 May 8 2
67 20559423 Precursor of advanced glycation end products mediates ER-stress-induced caspase-3 activation of human dermal fibroblasts through NAD(P)H oxidase 4. 2010 Jun 14 5
68 20837473 Gossypol induces death receptor-5 through activation of the ROS-ERK-CHOP pathway and sensitizes colon cancer cells to TRAIL. 2010 Nov 12 1
69 21472292 Tanshinone IIA may inhibit the growth of small cell lung cancer H146 cells by up-regulating the Bax/Bcl-2 ratio and decreasing mitochondrial membrane potential. 2010 Jul-Aug 1
70 19345731 Withaferin A sensitizes TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP. 2009 Jun 15 3
71 18630529 The role of Ca2+ in baicalein-induced apoptosis in human breast MDA-MB-231 cancer cells through mitochondria- and caspase-3-dependent pathway. 2008 May-Jun 1
72 18852146 15-deoxy-Delta12,14-prostaglandin J2 up-regulates death receptor 5 gene expression in HCT116 cells: involvement of reactive oxygen species and C/EBP homologous transcription factor gene transcription. 2008 Oct 3
73 16386220 [Physiological and physiopathological consequences of mitochondrial reactive oxygen species]. 2006 Jan 2
74 16400006 Expression and function of C/EBP homology protein (GADD153) in podocytes. 2006 Jan 1
75 16972258 N-(4-hydroxyphenyl)retinamide induces apoptosis in human retinal pigment epithelial cells: retinoic acid receptors regulate apoptosis, reactive oxygen species generation, and the expression of heme oxygenase-1 and Gadd153. 2006 Dec 1
76 12880976 Induction of GADD153 and Bak: novel molecular targets of fenretinide-induced apoptosis of neuroblastoma. 2003 Jul 18 1
77 12907753 CCAAT/enhancer-binding protein-homologous protein expression and transcriptional activity are regulated by 3',5'-cyclic adenosine monophosphate in thyroid cells. 2003 Nov 1
78 14635187 Induction of GADD gene expression by phenethylisothiocyanate in human colon adenocarcinoma cells. 2003 Dec 15 2
79 11158311 Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. 2001 Feb 2
80 19002820 Heat induction of reporter gene expression via the gadd153 promoter and its possible application to hyperthermia treatment of cancer. 2000 Jul 1