Losartan

angiotensinogen ; Homo sapiens







539 Article(s)
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51 25219839 Effect of angiotensin II on STAT3 mediated atrial structural remodeling. 2014 Aug 2
52 25301384 Angiotensin-(1-7) modulates angiotensin II-induced vasoconstriction in human mammary artery. 2014 Dec 1
53 22887358 Inhibition of PTEN expression and activity by angiotensin II induces proliferation and migration of vascular smooth muscle cells. 2013 Jan 1
54 23054367 Ethanol and vitamin D receptor in T cell apoptosis. 2013 Mar 1
55 23092556 Angiotensin II type 1 receptor antagonists inhibit cell proliferation and angiogenesis in breast cancer. 2013 Jan 28 1
56 23221601 Angiotensin II and III metabolism and effects on steroid production in the HAC15 human adrenocortical cell line. 2013 Jan 1
57 23407636 Opposite effect of angiotensin receptor blockade on CXCL8 production and CXCR1/2 expression of angiotensin II-treated THP-1 monocytes. 2013 Mar 2
58 23509080 A novel role for c-Myc in G protein-coupled receptor kinase 4 (GRK4) transcriptional regulation in human kidney proximal tubule cells. 2013 May 1
59 23569086 Angiotensin II stimulates basolateral 10-pS Cl channels in the thick ascending limb. 2013 Jun 1
60 24021937 Angiotensin II induces C-reactive protein expression via AT1-ROS-MAPK-NF-κB signal pathway in hepatocytes. 2013 4
61 24194850 Ang II enhances noradrenaline release from sympathetic nerve endings thus contributing to the up-regulation of metalloprotease-2 in aortic dissection patients' aorta wall. 2013 1
62 24552291 A novel design of combining the angiotensin converting enzyme (ACE) inhibitor captopril with the angiotensin receptor blocker (ARB) losartan using homo coupling via PEG diacid linker. 2013 Dec 1
63 21481898 Angiotensin-II induced nitric oxide production during buffalo sperm capacitation and acrosome reaction. 2012 Apr 1
64 22217266 Losartan inhibits STAT1 activation and protects human glomerular mesangial cells from angiotensin II induced premature senescence. 2012 Jan 2
65 22388234 An initial reduction in serum uric acid during angiotensin receptor blocker treatment is associated with cardiovascular protection: a post-hoc analysis of the RENAAL and IDNT trials. 2012 May 2
66 22549450 Losartan attenuates human monocyte-derived dendritic cell immune maturation via downregulation of lectin-like oxidized low-density lipoprotein receptor-1. 2012 Aug 5
67 22613986 Angiotensin II induces angiogenic factors production partly via AT1/JAK2/STAT3/SOCS3 signaling pathway in MHCC97H cells. 2012 1
68 22659808 Rosiglitazone inhibits angiotensin II-induced C-reactive protein production in human aortic endothelial cells through regulating AT(1)-ROS-MAPK signal pathway. 2012 Sep 2
69 22784310 Implication of multiple signaling pathways in the regulation of angiotensin II induced enhanced expression of Giα proteins in vascular smooth muscle cells. 2012 Aug 1
70 20592661 Drug therapy of heart failure: an immunologic view. 2011 Sep 2
71 20882268 Increased serum potassium affects renal outcomes: a post hoc analysis of the Reduction of Endpoints in NIDDM with the Angiotensin II Antagonist Losartan (RENAAL) trial. 2011 Jan 1
72 20927043 Angiotensin II diminishes the effect of SGK1 on the WNK4-mediated inhibition of ROMK1 channels. 2011 Feb 2
73 21153603 ANG II type I receptor antagonism improved nitric oxide production and enhanced eNOS and PKB/Akt expression in hearts from a rat model of insulin resistance. 2011 Mar 1
74 21325823 Angiotensin II induces the expression of c-reactive protein via MAPK-dependent signal pathway in U937 macrophages. 2011 3
75 21331055 Effect of angiotensin AT1 receptor blockade on sympathetic responses to handgrip in healthy men. 2011 May 1
76 21468560 Change of telomere length in angiotensin II-induced human glomerular mesangial cell senescence and the protective role of losartan. 2011 Mar-Apr 2
77 21511303 Effect of angiotensin II and its receptor antagonists on human corpus cavernous contractility and oxidative stress: modulation of nitric oxide mediated relaxation. 2011 Jun 2
78 21632472 Effect of a reduction in uric acid on renal outcomes during losartan treatment: a post hoc analysis of the reduction of endpoints in non-insulin-dependent diabetes mellitus with the Angiotensin II Antagonist Losartan Trial. 2011 Jul 1
79 21660462 Angiotensin II downregulates catalase expression and activity in vascular adventitial fibroblasts through an AT1R/ERK1/2-dependent pathway. 2011 Dec 1
80 21663700 PLCβ1-SHP-2 complex, PLCβ1 tyrosine dephosphorylation and SHP-2 phosphatase activity: a new part of Angiotensin II signaling? 2011 Jun 13 1
81 19812300 Expression and distribution of NADPH oxidase isoforms in human myometrium--role in angiotensin II-induced hypertrophy. 2010 Feb 2
82 20035777 FURO/CAP: a protocol for sodium intake sensitization. 2010 Mar 30 1
83 20436376 A single-nucleotide polymorphism of alanine to threonine at position 163 of the human angiotensin II type 1 receptor impairs Losartan affinity. 2010 Jun 1
84 20458733 Angiotensin II/angiotensin II type I receptor (AT1R) signaling promotes MCF-7 breast cancer cells survival via PI3-kinase/Akt pathway. 2010 Oct 3
85 20497092 Losartan: the dose does it. 2010 Aug 2
86 20538278 Angiotensin II induces C-reactive protein expression through ERK1/2 and JNK signaling in human aortic endothelial cells. 2010 Sep 3
87 20563831 The effect of the expression of angiotensin II on extracellular matrix metalloproteinase inducer (EMMPRIN) in macrophages is mediated via the AT1/COX-2/PGE2 pathway. 2010 Dec 1
88 20937029 Substituted benzimidazole derivatives as angiotensin II-AT1 receptor antagonist: a review. 2010 Dec 1
89 21472252 Role of the JAK2/STAT pathway and losartan in human glomerular mesangial cell senescence. 2010 May-Jun 2
90 18973754 Angiotensin II induces vascular endothelial growth factor synthesis in mesenchymal stem cells. 2009 Jan 1 1
91 19086920 Extracellular matrix metalloproteinase inducer (EMMPRIN) is present in smooth muscle cells of human aneurysmal aorta and is induced by angiotensin II in vitro. 2009 May 1 1
92 19211919 Involvement of redox-sensitive extracellular-regulated kinases in angiotensin II-induced interleukin-6 expression in pancreatic acinar cells. 2009 May 1
93 19240212 Angiotensin II signaling increases activity of the renal Na-Cl cotransporter through a WNK4-SPAK-dependent pathway. 2009 Mar 17 1
94 19338654 Angiotensin II directly regulates intestinal epithelial NHE3 in Caco2BBE cells. 2009 Apr 1 2
95 19397700 Angiotensin II activates connective tissue growth factor and induces extracellular matrix changes involving Smad/activation and p38 mitogen-activated protein kinase signalling pathways in human dermal fibroblasts. 2009 Nov 1
96 19429096 Angiotensin II inhibits GABAergic synaptic transmission in dorsolateral periaqueductal gray neurons. 2009 May 8 1
97 19487683 AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist. 2009 Jun 23 1
98 19517575 Angiotensin II up-regulates PAX2 oncogene expression and activity in prostate cancer via the angiotensin II type I receptor. 2009 Sep 1 1
99 19601700 The value of irbesartan in the management of hypertension. 2009 Aug 1
100 19628656 Effects of losartan on hepatic expression of nonphagocytic NADPH oxidase and fibrogenic genes in patients with chronic hepatitis C. 2009 Oct 1