Losartan

angiotensinogen ; Homo sapiens







539 Article(s)
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1 35106453 Attenuation of SARS-CoV-2 infection by losartan in human kidney organoids. 2022 Feb 18 1
2 35183655 Angiotensinogen uptake and stimulation of oxidative stress in human pigment retinal epithelial cells. 2022 Jun 1
3 35347130 Losartan protects human stem cell-derived cardiomyocytes from angiotensin II-induced alcoholic cardiotoxicity. 2022 Mar 28 1
4 33504092 From Angiotensin II to Cyclic Peptides and Angiotensin Receptor Blockers (ARBs): Perspectives of ARBs in COVID-19 Therapy. 2021 Jan 25 1
5 33624364 Elevated angiotensin II induces platelet apoptosis through promoting oxidative stress in an AT1R-dependent manner during sepsis. 2021 Apr 2
6 33726768 Angiotensin II-induced upregulation of SGLT1 and 2 contributes to human microparticle-stimulated endothelial senescence and dysfunction: protective effect of gliflozins. 2021 Mar 16 1
7 33807929 The Angiotensin II Receptor Blocker Losartan Sensitizes Human Liver Cancer Cells to Lenvatinib-Mediated Cytostatic and Angiostatic Effects. 2021 Mar 5 3
8 33822013 Angiotensin II up-regulates sodium-glucose co-transporter 2 expression and SGLT2 inhibitor attenuates Ang II-induced hypertensive renal injury in mice. 2021 Apr 16 2
9 34270373 Angiotensin II-induced overexpression of sirtuin 1 contributes to enhanced expression of Giα proteins and hyperproliferation of vascular smooth muscle cells. 2021 Sep 1 1
10 34572782 Novel Insights into the Antagonistic Effects of Losartan against Angiotensin II/AGTR1 Signaling in Glioblastoma Cells. 2021 Sep 10 2
11 31177627 Angiotensin II inhibits P-glycoprotein in intestinal epithelial cells. 2020 Jan 2
12 31655485 Angiotensin involvement in trauma processing-exploring candidate neurocognitive mechanisms of preventing post-traumatic stress symptoms. 2020 Feb 1
13 31957305 Hyperbaric oxygen activates visfatin expression and angiogenesis via angiotensin II and JNK pathway in hypoxic human coronary artery endothelial cells. 2020 Feb 1
14 30677511 Involvement of estrogen receptor and GPER in bisphenol A induced proliferation of vascular smooth muscle cells. 2019 Apr 2
15 30988133 The human duodenal mucosa harbors all components for a local renin angiotensin system. 2019 Apr 30 1
16 31061349 [Angiotensin II Regulates Excitability and Contractile Functions of Myocardium and Smooth Muscles through Autonomic Nervous Transmission]. 2019 1
17 31155138 The Effects of the Angiotensin II Receptor Antagonist Losartan on Appetitive Versus Aversive Learning: A Randomized Controlled Trial. 2019 Sep 1 1
18 29119534 Angiotensin II Causes Neuronal Damage in Stretch-Injured Neurons: Protective Effects of Losartan, an Angiotensin T1 Receptor Blocker. 2018 Jul 3
19 29159869 Acute intermittent hypoxia with concurrent hypercapnia evokes P2X and TRPV1 receptor-dependent sensory long-term facilitation in naïve carotid bodies. 2018 Aug 1
20 29455433 Intracrine action of angiotensin II in mesangial cells: subcellular distribution of angiotensin II receptor subtypes AT1 and AT2. 2018 Nov 1
21 29907995 Fifteen years of LIFE (Losartan Intervention for Endpoint Reduction in Hypertension)-Lessons learned for losartan: An "old dog playing good tricks". 2018 Jun 15 1
22 30031758 Angiotensin receptor blockade attenuates cholangiocarcinoma cell growth by inhibiting the oncogenic activity of Yes-associated protein. 2018 Oct 10 1
23 30564297 Significance of intranuclear angiotensin-II type 2 receptor in oral squamous cell carcinoma. 2018 Nov 27 1
24 27400779 Uric acid stimulates proliferative pathways in vascular smooth muscle cells through the activation of p38 MAPK, p44/42 MAPK and PDGFRβ. 2017 Apr 1
25 28157237 Mechanisms underlying the cardiac antifibrotic effects of losartan metabolites. 2017 Feb 3 1
26 28548953 From rapalogs to anti-aging formula. 2017 May 30 1
27 28578904 Role of RAS/Wnt/β-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy. 2017 Aug 1 1
28 28652473 Increased Angiotensin II Sensitivity Contributes to Microvascular Dysfunction in Women Who Have Had Preeclampsia. 2017 Aug 1
29 28793067 Farmácia Popular Program: pharmaceutical market analysis of antihypertensive acting on the renin-angiotensin system medicines. 2017 Aug 1
30 28849131 Periostin cross‑reacts with the renin‑angiotensin system during liver fibrosis development. 2017 Nov 2
31 27100622 Retinol-Binding Protein 4 Induces Cardiomyocyte Hypertrophy by Activating TLR4/MyD88 Pathway. 2016 Jun 2
32 27422988 Local renin-angiotensin system mediates endothelial dilator dysfunction in aging arteries. 2016 Sep 1 1
33 25760379 Angiotensin II promotes melanogenesis via angiotensin II type 1 receptors in human melanocytes. 2015 Jul 1
34 25858030 Crosstalk between the renal sympathetic nerve and intrarenal angiotensin II modulates proximal tubular sodium reabsorption. 2015 Apr 20 1
35 26045756 Local renin-angiotensin system regulates hypoxia-induced vascular endothelial growth factor synthesis in mesenchymal stem cells. 2015 1
36 26052867 Activation of angiotensin II type 1 receptors and contractile activity in human sigmoid colon in vitro. 2015 Sep 1
37 26171169 Advanced glycation end products upregulate angiopoietin-like protein 4 expression by activating the renin-angiotensin system in endothelial cells. 2015 Jul 1
38 23380567 Elevated circulating alpha-klotho by angiotensin II receptor blocker losartan is associated with reduction of albuminuria in type 2 diabetic patients. 2014 Dec 1
39 23390187 Angiotensin modulates human mammary epithelial cell motility. 2014 Dec 1
40 23459786 AngII-induced glomerular mesangial cell proliferation inhibited by losartan via changes in intracellular calcium ion concentration. 2014 May 4
41 24144549 The anteroventral third ventricle region is critical for the behavioral desensitization caused by repeated injections of angiotensin II. 2014 Jan 1 2
42 24210590 Estimated GFR decline as a surrogate end point for kidney failure: a post hoc analysis from the Reduction of End Points in Non-Insulin-Dependent Diabetes With the Angiotensin II Antagonist Losartan (RENAAL) study and Irbesartan Diabetic Nephropathy Trial (IDNT). 2014 Feb 1
43 24259418 Bone marrow mononuclear cell angiogenic competency is suppressed by a high-salt diet. 2014 Jan 15 1
44 24327206 Endogenous endothelin 1 mediates angiotensin II-induced hypertrophy in electrically paced cardiac myocytes through EGFR transactivation, reactive oxygen species and NHE-1. 2014 Sep 1
45 24632204 Losartan inhibits endothelial-to-mesenchymal transformation in mitral valve endothelial cells by blocking transforming growth factor-β-induced phosphorylation of ERK. 2014 Apr 18 2
46 24931486 Pathophysiology and Japanese clinical characteristics in Marfan syndrome. 2014 Aug 1
47 24976017 Angiotensin II-regulated microRNA 483-3p directly targets multiple components of the renin-angiotensin system. 2014 Oct 1
48 24986244 Role of CD2-associated protein in podocyte apoptosis and proteinuria induced by angiotensin II. 2014 Sep 1
49 25014541 Dual targeting of angiotensin receptors (AGTR1 and AGTR2) in epithelial ovarian carcinoma. 2014 Oct 2
50 25070892 The angiotensin II type 1 receptor (AT1R) closely interacts with large conductance voltage- and Ca2+-activated K+ (BK) channels and inhibits their activity independent of G-protein activation. 2014 Sep 12 2