Azathioprine

thiopurine S-methyltransferase ; Homo sapiens







283 Article(s)
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251 10993211 Detection assay of rare variants of the thiopurine methyltransferase gene by PCR-RFLP using a mismatch primer in a Japanese population. 2000 Sep 2
252 11007234 Allelic variants of the thiopurine S-methyltransferase deficiency in patients with ulcerative colitis and in healthy controls. 2000 Sep 2
253 11012112 Thiopurine methyltransferase in red blood cells of dogs, cats, and horses. 2000 Sep-Oct 2
254 11012121 Demonstration of thiopurine methyltransferase activity in the erythrocytes of cats. 2000 Sep-Oct 2
255 11025471 Frequency of thiopurine S-methyltransferase genetic variation in Thai children with acute leukemia. 2000 Oct 2
256 11093885 [Aplasia after azathioprine administration: role of the thiopurine methyltransferase genetic polymorphism]. 2000 Sep 16 6
257 9931345 Thiopurine methyltransferase alleles in British and Ghanaian populations. 1999 Feb 2
258 10213363 Pharmacogenetics as a molecular basis for individualized drug therapy: the thiopurine S-methyltransferase paradigm. 1999 Mar 1
259 10461478 Identification of thiopurine methyltransferase (TPMT) polymorphisms cannot predict myelosuppression in systemic lupus erythematosus patients taking azathioprine. 1999 Jul 3
260 10594482 Thiopurine methyltransferase activity and its relationship to the occurrence of rejection episodes in paediatric renal transplant recipients treated with azathioprine. 1999 Dec 4
261 10628931 Thiopurine methyltransferase genotype and the toxicity of azathioprine in Japanese. 1999 Dec 11
262 10634140 Ethnic differences in thiopurine methyltransferase pharmacogenetics: evidence for allele specificity in Caucasian and Kenyan individuals. 1999 Dec 2
263 9510461 Pharmacokinetics, dose adjustments, and 6-mercaptopurine/methotrexate drug interactions in two patients with thiopurine methyltransferase deficiency. 1998 Jan 1
264 9695718 Isolation of a human thiopurine S-methyltransferase (TPMT) complementary DNA with a single nucleotide transition A719G (TPMT*3C) and its association with loss of TPMT protein and catalytic activity in humans. 1998 Jul 2
265 9778228 Reduced thiopurine methyltransferase activity and development of side effects of azathioprine treatment in patients with rheumatoid arthritis. 1998 Oct 3
266 9780118 The monitoring of immunosuppressive drugs: a pharmacodynamic approach. 1998 Oct 5
267 9780130 Clinical implications of thiopurine methyltransferase--optimization of drug dosage and potential drug interactions. 1998 Oct 2
268 9103127 Molecular diagnosis of thiopurine S-methyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance. 1997 Apr 15 3
269 9200774 Possibilities for therapeutic drug monitoring of azathioprine: 6-thioguanine nucleotide concentrations and thiopurine methyltransferase activity in red blood cells. 1997 Jun 4
270 9336428 Azathioprine-induced severe pancytopenia due to a homozygous two-point mutation of the thiopurine methyltransferase gene in a patient with juvenile HLA-B27-associated spondylarthritis. 1997 Oct 3
271 9713575 Monitoring of cyclosporin and azathioprine in organ transplantation. 1997 2
272 8644731 Thiopurine S-methyltransferase deficiency: two nucleotide transitions define the most prevalent mutant allele associated with loss of catalytic activity in Caucasians. 1996 Apr 2
273 8689814 Thiopurine methyltransferase activity in a Korean population sample of children. 1996 Jul 2
274 8738760 Should 6-thioguanine nucleotides be monitored in heart transplant recipients given azathioprine? 1996 Jun 2
275 7570968 Monitoring of azathioprine-induced immunosuppression with thiopurine methyltransferase activity in kidney transplant recipients. 1995 Oct 15 6
276 7640156 Sulphasalazine inhibition of thiopurine methyltransferase: possible mechanism for interaction with 6-mercaptopurine and azathioprine. 1995 Apr 1
277 7818564 Azathioprine-related bone marrow toxicity and low activities of purine enzymes in patients with rheumatoid arthritis. 1995 Jan 5
278 7857117 The role of genetic variation in thiopurine methyltransferase activity and the efficacy and/or side effects of azathioprine therapy in dermatologic patients. 1995 Feb 4
279 8582469 Erythrocyte fraction affects red blood cell thiopurine methyltransferase activity. 1995 2
280 8687298 Monitoring of TPMT in heart transplant recipients under immunosuppressive therapy with azathioprine. 1995 Sep 4
281 1585469 The importance of thiopurine methyltransferase activity for the use of azathioprine in transplant recipients. 1992 May 5
282 2758725 Pharmacogenetics of acute azathioprine toxicity: relationship to thiopurine methyltransferase genetic polymorphism. 1989 Aug 4
283 3467886 Thiopurine pharmacogenetics in leukemia: correlation of erythrocyte thiopurine methyltransferase activity and 6-thioguanine nucleotide concentrations. 1987 Jan 2