7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide

cytochrome P450 family 1 subfamily B member 1 ; Homo sapiens







7 Article(s)
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1 27188524 Genetic polymorphisms in biotransformation enzymes for benzo[a]pyrene and related levels of benzo[a]pyrene-7,8-diol-9,10-epoxide-DNA adducts in Goeckerman therapy. 2016 Jul 25 3
2 20399842 The critical DNA damage by benzo(a)pyrene in lung tissues of smokers and approaches to preventing its formation. 2010 Sep 15 2
3 18489080 The pattern of p53 mutations caused by PAH o-quinones is driven by 8-oxo-dGuo formation while the spectrum of mutations is determined by biological selection for dominance. 2008 May 1
4 16557497 Quantification of benzo[a]pyrene diol epoxide DNA-adducts by stable isotope dilution liquid chromatography/tandem mass spectrometry. 2006 1
5 15720144 Competing roles of cytochrome P450 1A1/1B1 and aldo-keto reductase 1A1 in the metabolic activation of (+/-)-7,8-dihydroxy-7,8-dihydro-benzo[a]pyrene in human bronchoalveolar cell extracts. 2005 Feb 1
6 15808407 Induction of CYP1A1 and CYP1B1 and formation of carcinogen-DNA adducts in normal human mammary epithelial cells treated with benzo[a]pyrene. 2005 Apr 28 1
7 1423269 An improved fluorometric assay for dosimetry of benzo(a)pyrene diol-epoxide-DNA adducts in smokers' lung: comparisons with total bulky adducts and aryl hydrocarbon hydroxylase activity. 1992 Nov 15 1