4-hydroxyestradiol

cytochrome P450 family 1 subfamily B member 1 ; Homo sapiens







35 Article(s)
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Pub. Year
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1 32781018 Tryptophan and kynurenine stimulate human decidualization via activating Aryl hydrocarbon receptor: Short title: Kynurenine action on human decidualization. 2020 Sep 1
2 30680817 Oroxylin A, a methylated metabolite of baicalein, exhibits a stronger inhibitory effect than baicalein on the CYP1B1-mediated carcinogenic estradiol metabolite formation. 2019 Apr 2
3 31364906 Long-term exposure of 4-hydroxyestradiol induces the cancer cell characteristics via upregulating CYP1B1 in MCF-10A cells. 2019 Nov 4
4 31493422 CYP1B1 prevents proteasome-mediated XIAP degradation by inducing PKCε activation and phosphorylation of XIAP. 2019 Dec 2
5 27438141 4-Hydroxyestradiol induces mammary epithelial cell transformation through Nrf2-mediated heme oxygenase-1 overexpression. 2017 Jan 3 2
6 29290975 GPER is involved in the regulation of the estrogen-metabolizing CYP1B1 enzyme in breast cancer. 2017 Dec 5 1
7 26981862 CYP1B1 Enhances Cell Proliferation and Metastasis through Induction of EMT and Activation of Wnt/β-Catenin Signaling via Sp1 Upregulation. 2016 2
8 27687674 Targeting cytochrome P450 (CYP) 1B1 with steroid derivatives. 2016 Nov 1 2
9 25448748 Cytochrome P450 1 family and cancers. 2015 Mar 1
10 26123186 Differences in 4-hydroxyestradiol levels in leukocytes are related to CYP1A1(∗)2C, CYP1B1(∗)3 and COMT Val158Met allelic variants. 2015 Oct 2
11 24607809 Quercetin-3-O-glucronide inhibits noradrenaline binding to α2-adrenergic receptor, thus suppressing DNA damage induced by treatment with 4-hydroxyestradiol and noradrenaline in MCF-10A cells. 2014 Sep 2
12 25027399 Cytochrome P450 1B1 polymorphisms and risk of renal cell carcinoma in men. 2014 Oct 2
13 23283740 Common genetic variation in CYP1B1 is associated with concentrations of T₄, FT₃ and FT₄ in the sera of polycystic ovary syndrome patients. 2013 Apr 1
14 21920623 ERα phenotype, estrogen level, and benzo[a]pyrene exposure modulate tumor growth and metabolism of lung adenocarcinoma cells. 2012 Mar 4
15 23028769 Molecular basis for involvement of CYP1B1 in MYOC upregulation and its potential implication in glaucoma pathogenesis. 2012 1
16 21610218 Estrogen metabolism and exposure in a genotypic-phenotypic model for breast cancer risk prediction. 2011 Jul 1
17 20093341 Prostaglandin E2 induces CYP1B1 expression via ligand-independent activation of the ERalpha pathway in human breast cancer cells. 2010 Apr 2
18 20472053 N-acetylcysteine blocks formation of cancer-initiating estrogen-DNA adducts in cells. 2010 Aug 1 1
19 20632082 Association of CYP1B1 with hypersensitivity induced by taxane therapy in breast cancer patients. 2010 Nov 2
20 19276383 4-hydroxyestradiol induces anchorage-independent growth of human mammary epithelial cells via activation of IkappaB kinase: potential role of reactive oxygen species. 2009 Mar 15 1
21 18187806 Association of the CYP1B1*3 allele with survival in patients with prostate cancer receiving docetaxel. 2008 Jan 5
22 18256205 CYP1B1 is not a major determinant of the disposition of aromatase inhibitors in epithelial cells of invasive ductal carcinoma. 2008 May 1
23 18456490 Preferential induction of cytochrome P450 1A1 over cytochrome P450 1B1 in human breast epithelial cells following exposure to quercetin. 2008 May 1
24 17575138 Effects of tetramethoxystilbene on hormone-resistant breast cancer cells: biological and biochemical mechanisms of action. 2007 Jun 15 1
25 16893557 Regioselective 2-hydroxylation of 17beta-estradiol by rat cytochrome P4501B1. 2006 Nov 1 2
26 15901486 4-Hydroxyestradiol induces oxidative stress and apoptosis in human mammary epithelial cells: possible protection by NF-kappaB and ERK/MAPK. 2005 Oct 1 2
27 15142886 Resveratrol inhibits TCDD-induced expression of CYP1A1 and CYP1B1 and catechol estrogen-mediated oxidative DNA damage in cultured human mammary epithelial cells. 2004 Oct 1
28 15255550 Lack of association of CYP1 B1*3 polymorphism and ovarian cancer in a Caucasian population. 2004 Apr-Jun 1
29 14520706 Interactions between genetic polymorphism of cytochrome P450-1B1, sulfotransferase 1A1, catechol-o-methyltransferase and tobacco exposure in breast cancer risk. 2003 Nov 20 1
30 11156691 In situ hybridization and immunohistochemical analysis of cytochrome P450 1B1 expression in human normal tissues. 2001 Feb 1
31 10696569 Is estradiol a genotoxic mutagenic carcinogen? 2000 Feb 1
32 10698474 Genetic polymorphism of cytochrome P450-1B1 and risk of breast cancer. 2000 Feb 2
33 10862525 Polymorphisms in P450 CYP1B1 affect the conversion of estradiol to the potentially carcinogenic metabolite 4-hydroxyestradiol. 2000 Jun 2
34 10910054 Cytochrome P450 1B1 (CYP1B1) pharmacogenetics: association of polymorphisms with functional differences in estrogen hydroxylation activity. 2000 Jul 1 1
35 10067811 Quantitative analysis of constitutive and 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced cytochrome P450 1B1 expression in human lymphocytes. 1999 Feb 2