Polychlorinated Dibenzodioxins

cytochrome P450 family 1 subfamily B member 1 ; Homo sapiens







108 Article(s)
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1 34698116 FLII and MLL1 Cooperatively Regulate Aryl Hydrocarbon Receptor-Mediated Transcription in ARPE-19 Cells. 2021 Oct 16 3
2 31268702 Effect of Dioxins in Milk on the 3D Cultured Primary Buffalo Hepatocyte Model System. 2019 Jul 17 2
3 29541735 Quercetin-3-O-α-l-arabinopyranoside protects against retinal cell death via blue light-induced damage in human RPE cells and Balb-c mice. 2018 Apr 25 1
4 30092417 Effects of simvastatin on nuclear receptors, drug metabolizing enzymes and transporters expression in Human Umbilical Vein Endothelial Cells. 2018 Oct 3
5 32002969 Effects of simvastatin on nuclear receptors, drug metabolizing enzymes and transporters expression in Human Umbilical Vein Endothelial Cells. 2018 Sep 3
6 26990437 Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice. 2017 Jan 1
7 27837168 Editor's Highlight: Microbial-Derived 1,4-Dihydroxy-2-naphthoic Acid and Related Compounds as Aryl Hydrocarbon Receptor Agonists/Antagonists: Structure-Activity Relationships and Receptor Modeling. 2017 Feb 1
8 28886471 DNA damage by 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced p53-mediated apoptosis through activation of cytochrome P450/aryl hydrocarbon receptor. 2017 Oct 8
9 27358009 The role of AHR-inducible cytochrome P450s in metabolism of polyunsaturated fatty acids. 2016 Aug 1
10 27535091 Role of aryl hydrocarbon receptor polymorphisms on TCDD-mediated CYP1B1 induction and IgM suppression by human B cells. 2016 Oct 15 3
11 23700305 2,3,7,8-Tetrachlorodibenzo-p-dioxin modulates estradiol-induced aldehydic DNA lesions in human breast cancer cells through alteration of CYP1A1 and CYP1B1 expression. 2015 May 2
12 25327972 Hypoxia interferes with aryl hydrocarbon receptor pathway in hCMEC/D3 human cerebral microvascular endothelial cells. 2015 Feb 1
13 25637755 Stability of the aryl hydrocarbon receptor and its regulated genes in the low activity variant of Hepa-1 cell line. 2015 Mar 4 1
14 25858487 Aryl hydrocarbon receptor regulates CYP1B1 but not ABCB1 and ABCG2 in hCMEC/D3 human cerebral microvascular endothelial cells after TCDD exposure. 2015 Jul 10 5
15 26226543 Characterization and Biological Potency of Mono- to Tetra-Halogenated Carbazoles. 2015 Sep 1 2
16 26567990 Different regulation of aryl hydrocarbon receptor-regulated genes in response to dioxin in undifferentiated and neuronally differentiated human neuroblastoma SH-SY5Y cells. 2015 1
17 24299737 Zinc finger nuclease-mediated knockout of AHR or ARNT in human breast cancer cells abolishes basal and ligand-dependent regulation of CYP1B1 and differentially affects estrogen receptor α transactivation. 2014 Mar 5
18 24565903 IL-1 and TNF-α regulation of aryl hydrocarbon receptor (AhR) expression in HSY human salivary cells. 2014 Apr 2
19 24795504 Aryl hydrocarbon receptor (AhR) modulates cockroach allergen-induced immune responses through active TGFβ1 release. 2014 1
20 25110054 Metformin suppresses CYP1A1 and CYP1B1 expression in breast cancer cells by down-regulating aryl hydrocarbon receptor expression. 2014 Oct 1 2
21 25123135 Mammalian cytochrome P450-dependent metabolism of polychlorinated dibenzo-p-dioxins and coplanar polychlorinated biphenyls. 2014 Aug 13 2
22 25404385 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) inhibits human ovarian cancer cell proliferation. 2014 Dec 1
23 23275542 2,3,7,8-Tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase (TiPARP, ARTD14) is a mono-ADP-ribosyltransferase and repressor of aryl hydrocarbon receptor transactivation. 2013 Feb 1 1
24 23855798 Dioxin and estrogen signaling in lung adenocarcinoma cells with different aryl hydrocarbon receptor/estrogen receptor α phenotypes. 2013 Dec 1
25 22187486 Changes in expression of drug-metabolizing enzymes by single-walled carbon nanotubes in human respiratory tract cells. 2012 Mar 2
26 22560882 TGF-β1 signaling plays a dominant role in the crosstalk between TGF-β1 and the aryl hydrocarbon receptor ligand in prostate epithelial cells. 2012 Aug 1
27 22888330 Aryl Hydrocarbon Receptor-Mediated Perturbations in Gene Expression during Early Stages of CD4(+) T-cell Differentiation. 2012 1
28 19755661 Activation of the aryl hydrocarbon receptor pathway enhances cancer cell invasion by upregulating the MMP expression and is associated with poor prognosis in upper urinary tract urothelial cancer. 2010 Feb 2
29 20035023 Xenobiotic-metabolizing cytochromes p450 in human white adipose tissue: expression and induction. 2010 Apr 1
30 20171976 2,3,7,8-tetrachlorodibenzo-p-dioxin increases reactive oxygen species production in human endothelial cells via induction of cytochrome P4501A1. 2010 May 15 1
31 20417221 Metabolic bioactivation of oestradiol-17beta (E2beta) in mouse colon epithelial cells bearing ApcMin mutation. 2010 Oct 1
32 20619336 Involvement of aryl hydrocarbon receptor in basal and 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced expression of target genes in primary human hepatocytes. 2010 Sep 2
33 18842620 Roles of coactivator proteins in dioxin induction of CYP1A1 and CYP1B1 in human breast cancer cells. 2009 Jan 1
34 19038280 Disruption of period gene expression alters the inductive effects of dioxin on the AhR signaling pathway in the mouse liver. 2009 Feb 1 1
35 19324859 Expression of cytochrome P450 (CYP) enzymes in human nonpigmented ciliary epithelial cells: induction of CYP1B1 expression by TCDD. 2009 Jul 6
36 19376845 Resveratrol inhibits dioxin-induced expression of human CYP1A1 and CYP1B1 by inhibiting recruitment of the aryl hydrocarbon receptor complex and RNA polymerase II to the regulatory regions of the corresponding genes. 2009 Jul 1
37 19463925 Potent inhibition of human cytochrome P450 1B1 by tetramethoxystilbene. 2009 Aug 25 2
38 19919114 Effects of pomegranate chemical constituents/intestinal microbial metabolites on CYP1B1 in 22Rv1 prostate cancer cells. 2009 Nov 25 1
39 18089838 Dioxin-mediated up-regulation of aryl hydrocarbon receptor target genes is dependent on the calcium/calmodulin/CaMKIalpha pathway. 2008 Mar 1
40 18402469 Comparisons of (+/-)-benzo[a]pyrene-trans-7,8-dihydrodiol activation by human cytochrome P450 and aldo-keto reductase enzymes: effect of redox state and expression levels. 2008 May 3
41 18434241 High potency of bioactivation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in mouse colon epithelial cells with Apc(Min) mutation. 2008 May 31 1
42 18558727 2,3,7,8-Tetrachlorodibenzo-p-dioxin modulates the induction of DNA strand breaks and poly(ADP-ribose) polymerase-1 activation by 17beta-estradiol in human breast carcinoma cells through alteration of CYP1A1 and CYP1B1 expression. 2008 Jul 1
43 19138946 Resveratrol prevents estrogen-DNA adduct formation and neoplastic transformation in MCF-10F cells. 2008 Jul 4
44 17257637 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) exposure of normal human dermal fibroblasts results in AhR-dependent and -independent changes in gene expression. 2007 Apr 1 2
45 17785579 A dioxin-responsive enhancer 3' of the human CYP1A2 gene. 2007 Dec 4
46 16237193 Preferential induction of CYP1A1 and CYP1B1 in CCSP-positive cells. 2006 Jan 1
47 16271822 Inhibition of human cytochrome CYP 1 enzymes by flavonoids of St. John's wort. 2006 Jan 16 1
48 16411658 Competing roles of aldo-keto reductase 1A1 and cytochrome P4501B1 in benzo[a]pyrene-7,8-diol activation in human bronchoalveolar H358 cells: role of AKRs in P4501B1 induction. 2006 Jan 1
49 16527260 Cytochrome P450 expression and metabolic activation of cooked food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in MCF10A breast epithelial cells. 2006 Apr 15 1
50 16704738 Identification of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-inducible genes in human amniotic epithelial cells. 2006 May 17 1