Dioxins

cytochrome P450 family 1 subfamily B member 1 ; Homo sapiens







34 Article(s)
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1 31733235 Human CYP1B1-dependent genotoxicity of dioxin-like polychlorinated biphenyls in mammalian cells. 2020 Jan 15 1
2 26226543 Characterization and Biological Potency of Mono- to Tetra-Halogenated Carbazoles. 2015 Sep 1 1
3 26997841 CYP1B1-mediated Pathobiology of Primary Congenital Glaucoma. 2015 Sep-Dec 1
4 24926919 Genetic variation in the CYP1A1 gene is related to circulating PCB118 levels in a population-based sample. 2014 Aug 1
5 25257533 Defining molecular sensors to assess long-term effects of pesticides on carcinogenesis. 2014 Sep 25 1
6 20631054 Role of epigenetic mechanisms in differential regulation of the dioxin-inducible human CYP1A1 and CYP1B1 genes. 2010 Oct 5
7 20829355 The aryl hydrocarbon receptor-interacting protein (AIP) is required for dioxin-induced hepatotoxicity but not for the induction of the Cyp1a1 and Cyp1a2 genes. 2010 Nov 12 1
8 20846786 Inhibition of aryl hydrocarbon receptor-dependent transcription by resveratrol or kaempferol is independent of estrogen receptor α expression in human breast cancer cells. 2010 Dec 28 2
9 18842620 Roles of coactivator proteins in dioxin induction of CYP1A1 and CYP1B1 in human breast cancer cells. 2009 Jan 5
10 19158084 HDAC6 modulates Hsp90 chaperone activity and regulates activation of aryl hydrocarbon receptor signaling. 2009 Mar 20 1
11 19255421 EGF receptor signaling blocks aryl hydrocarbon receptor-mediated transcription and cell differentiation in human epidermal keratinocytes. 2009 Mar 17 1
12 19287966 CYP1B1, but not CYP1A1, is downregulated by promoter methylation in colorectal cancers. 2009 Apr 1
13 19376845 Resveratrol inhibits dioxin-induced expression of human CYP1A1 and CYP1B1 by inhibiting recruitment of the aryl hydrocarbon receptor complex and RNA polymerase II to the regulatory regions of the corresponding genes. 2009 Jul 4
14 19460354 Activation function 2 mediates dioxin-induced recruitment of estrogen receptor alpha to CYP1A1 and CYP1B1. 2009 Jul 24 4
15 19736056 Associations of common variants in genes involved in metabolism and response to exogenous chemicals with risk of multiple myeloma. 2009 Oct 1
16 18583386 Reactive oxygen species from the uncoupling of human cytochrome P450 1B1 may contribute to the carcinogenicity of dioxin-like polychlorinated biphenyls. 2008 Nov 5
17 18849443 Elevated expression of CYP1A1 and gamma-SYNUCLEIN in human ectopic (ovarian) endometriosis compared with eutopic endometrium. 2008 Nov 1
18 17785579 A dioxin-responsive enhancer 3' of the human CYP1A2 gene. 2007 Dec 1
19 15596250 CYP1A1 and CYP1B1 genotypes, haplotypes, and TCDD-induced gene expression in subjects from Seveso, Italy. 2005 Feb 14 2
20 15659568 Cytochrome P450 1A1 and 1B1 in human blood lymphocytes are not suitable as biomarkers of exposure to dioxin-like compounds: polymorphisms and interindividual variation in expression and inducibility. 2005 May 3
21 16115918 Cytochrome P450 1B1 is overexpressed and regulated by hypomethylation in prostate cancer. 2005 Aug 15 3
22 15075793 Interaction between genetic polymorphism of cytochrome P450-1B1 and environmental pollutants in breast cancer risk. 2004 Feb 1
23 15142886 Resveratrol inhibits TCDD-induced expression of CYP1A1 and CYP1B1 and catechol estrogen-mediated oxidative DNA damage in cultured human mammary epithelial cells. 2004 Oct 1
24 12646511 Aryl hydrocarbon hydroxylase represents CYP1B1, and not CYP1A1, in human freshly isolated white cells: trimodal distribution of Japanese population according to induction of CYP1B1 mRNA by environmental dioxins. 2003 Mar 4
25 12902195 Effects of several dioxin-like compounds on estrogen metabolism in the malignant MCF-7 and nontumorigenic MCF-10A human mammary epithelial cell lines. 2003 Aug 1 1
26 12376470 The redox protein thioredoxin-1 regulates the constitutive and inducible expression of the estrogen metabolizing cytochromes P450 1B1 and 1A1 in MCF-7 human breast cancer cells. 2002 Oct 1
27 11156691 In situ hybridization and immunohistochemical analysis of cytochrome P450 1B1 expression in human normal tissues. 2001 Feb 2
28 10702233 Transcriptional regulation of the human CYP1B1 gene. Evidence for involvement of an aryl hydrocarbon receptor response element in constitutive expression. 2000 Mar 10 1
29 10764452 Expression of dioxin-related transactivating factors and target genes in human eutopic endometrial and endometriotic tissues. 2000 Apr 2
30 10067811 Quantitative analysis of constitutive and 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced cytochrome P450 1B1 expression in human lymphocytes. 1999 Feb 4
31 9744540 Expression of CYP1B1 but not CYP1A1 by primary cultured human mammary stromal fibroblasts constitutively and in response to dioxin exposure: role of the Ah receptor. 1998 Aug 1
32 9802319 Cytochrome P450 1B1: a major P450 isoenzyme in human blood monocytes and macrophage subsets. 1998 Nov 1 1
33 9230218 Tumor-specific expression of cytochrome P450 CYP1B1. 1997 Jul 15 1
34 9328177 Metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) by human cytochrome P4501B1. 1997 Sep 2