Lactic Acid

basigin (Ok blood group) ; Homo sapiens







36 Article(s)
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1 34619707 Coexpression of MCT1 and MCT4 in ALK-positive Anaplastic Large Cell Lymphoma: Diagnostic and Therapeutic Implications. 2022 Feb 1 1
2 35054026 BSG (CD147) Serum Level and Genetic Variants Are Associated with Overall Survival in Acute Myeloid Leukaemia. 2022 Jan 10 3
3 33406400 Di-methylation of CD147-K234 Promotes the Progression of NSCLC by Enhancing Lactate Export. 2021 Jan 5 2
4 33770122 Basigin drives intracellular accumulation of l-lactate by harvesting protons and substrate anions. 2021 1
5 33927478 Silencing of CD147 inhibits hepatic stellate cells activation related to suppressing aerobic glycolysis via hedgehog signaling. 2021 Apr 1
6 33967078 HIF-1α may promote glycolysis in psoriasis vulgaris via upregulation of CD147 and GLUT1. 2021 Apr 28 3
7 31723238 CAIX forms a transport metabolon with monocarboxylate transporters in human breast cancer cells. 2020 Feb 1
8 32754264 HSPA12A unstabilizes CD147 to inhibit lactate export and migration in human renal cell carcinoma. 2020 1
9 32887638 Tissue expression of lactate transporters (MCT1 and MCT4) and prognosis of malignant pleural mesothelioma (brief report). 2020 Sep 4 2
10 33178600 Psychological Stress Up-Regulates CD147 Expression Through Beta-Arrestin1/ERK to Promote Proliferation and Invasiveness of Glioma Cells. 2020 1
11 29634399 Down-Regulated miR-125a-5p Promotes the Reprogramming of Glucose Metabolism and Cell Malignancy by Increasing Levels of CD147 in Thyroid Cancer. 2018 May 1
12 29695106 BSG and MCT1 Genetic Variants Influence Survival in Multiple Myeloma Patients. 2018 Apr 24 3
13 30463017 Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism. 2018 Nov 20 1
14 26996298 Leptin contributes to long-term stabilization of HIF-1α in cancer cells subjected to oxygen limiting conditions. 2016 Jun 28 1
15 27294876 Immunomodulatory drugs disrupt the cereblon-CD147-MCT1 axis to exert antitumor activity and teratogenicity. 2016 Jul 1
16 25196575 Differential expression of lactic acid isomers, extracellular matrix metalloproteinase inducer, and matrix metalloproteinase-8 in vaginal fluid from women with vaginal disorders. 2015 Nov 1
17 25403912 Genetic disruption of lactate/H+ symporters (MCTs) and their subunit CD147/BASIGIN sensitizes glycolytic tumor cells to phenformin. 2015 Jan 1 2
18 25456395 Expression of lactate/H⁺ symporters MCT1 and MCT4 and their chaperone CD147 predicts tumor progression in clear cell renal cell carcinoma: immunohistochemical and The Cancer Genome Atlas data analyses. 2015 Jan 1
19 25755717 RNA interference targeting CD147 inhibits the proliferation, invasiveness, and metastatic activity of thyroid carcinoma cells by down-regulating glycolysis. 2015 3
20 26284589 Knock out of the BASIGIN/CD147 chaperone of lactate/H+ symporters disproves its pro-tumour action via extracellular matrix metalloproteases (MMPs) induction. 2015 Sep 22 3
21 24801417 CD147 promotes reprogramming of glucose metabolism and cell proliferation in HCC cells by inhibiting the p53-dependent signaling pathway. 2014 Oct 1
22 24857275 Prognostic significance of lactate/proton symporters MCT1, MCT4, and their chaperone CD147 expressions in urothelial carcinoma of the bladder. 2014 Jul 1
23 24013424 CD147 regulates the expression of MCT1 and lactate export in multiple myeloma cells. 2013 Oct 1 1
24 21930917 CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors. 2011 Oct 4 7
25 20021214 Tumor metabolism of lactate: the influence and therapeutic potential for MCT and CD147 regulation. 2010 Jan 1
26 18778892 A CD147-targeting siRNA inhibits the proliferation, invasiveness, and VEGF production of human malignant melanoma cells by down-regulating glycolysis. 2009 Jan 8 5
27 19176383 Hyaluronan, CD44, and emmprin regulate lactate efflux and membrane localization of monocarboxylate transporters in human breast carcinoma cells. 2009 Feb 15 1
28 19505879 CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models. 2009 Oct 2
29 18379211 Mitochondrial lactate oxidation complex and an adaptive role for lactate production. 2008 Mar 1
30 18616931 Blocking CD147 induces cell death in cancer cells through impairment of glycolytic energy metabolism. 2008 Sep 12 1
31 18761711 Basal and stimulated lactate fluxes in primary cultures of astrocytes are differentially controlled by distinct proteins. 2008 Nov 4
32 17483329 Monocarboxylate transporter 4 regulates maturation and trafficking of CD147 to the plasma membrane in the metastatic breast cancer cell line MDA-MB-231. 2007 May 1 2
33 15901826 Metabolic activation-related CD147-CD98 complex. 2005 Aug 1
34 16260747 Mechanisms regulating tissue-specific polarity of monocarboxylate transporters and their chaperone CD147 in kidney and retinal epithelia. 2005 Nov 8 2
35 14606962 A novel form of the membrane protein CD147 that contains an extra Ig-like domain and interacts homophilically. 2003 Nov 7 1
36 10921872 CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression. 2000 Aug 1 1