1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine

monoamine oxidase B ; Homo sapiens







93 Article(s)
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51 1447747 Design, synthesis, and biological evaluation of novel 4-substituted 1-methyl-1,2,3,6-tetrahydropyridine analogs of MPTP. 1992 Nov 13 1
52 1504260 Quantitative structure-metabolism relationship analyses of MAO-mediated toxication of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and analogues. 1992 May-Jun 2
53 1610807 Interaction of flexible analogs of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and of N-methyl-4-phenylpyridinium with highly purified monoamine oxidase A and B. 1992 Jun 23 2
54 1641061 Interactions of the neurotoxin MPTP and its demethylated derivative (PTP) with monoamine oxidase-B. 1992 Aug 3
55 1815982 MPTP mechanisms of neurotoxicity and their implications for Parkinson's disease. 1991 Dec 12 1
56 2023912 Human monoamine oxidase A and B genes exhibit identical exon-intron organization. 1991 May 1 2
57 2029154 Drug treatment of Parkinson's disease: current concepts. 1991 Jan 1
58 2064731 Acetyl-levo-carnitine protects against MPTP-induced parkinsonism in primates. 1991 2
59 2128498 Monoamine oxidase and the bioactivation of MPTP and related neurotoxins: relevance to DATATOP. 1990 1
60 2246119 The hypothalamus in MPTP-induced parkinsonism. 1990 Aug 1
61 2266365 Platelet monoamine oxidase B activity in parkinsonian patients. 1990 Oct 4
62 2358804 The interactions of monoamine oxidase with some derivatives of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). 1990 1
63 2543694 [The effects of 1-methyl-4-phenylpyridine (MPP+) on O2- generation by neutrophils]. 1989 Feb 1
64 2568664 Brain monoamine oxidase (MAO) B: a unique neurotoxin and neurotransmitter producing enzyme. 1989 2
65 2753987 [A new procedure for the determination of N-methylisoquinolinium ion, and its application]. 1989 Jun 2
66 2788162 Deuterium isotope effect measurements on the interactions of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine with monoamine oxidase B. 1989 Aug 15 5
67 2788253 Intracerebral microdialysis neurotoxicity studies of quinoline and isoquinoline derivatives related to MPTP/MPP+. 1989 May 22 1
68 2809594 Oxidation of analogs of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by monoamine oxidases A and B and the inhibition of monoamine oxidases by the oxidation products. 1989 Dec 7
69 2963592 The mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity: role of intracellular calcium. 1988 Feb 1 2
70 3068045 [The bases of MPTP neurotoxicity]. 1988 Nov-Dec 1
71 3129982 MPTP toxicity: implications for research in Parkinson's disease. 1988 2
72 3258013 Attenuation of MPTP-induced dopaminergic neurotoxicity by a serotonin uptake blocker. 1988 4
73 3258018 Potent neurotoxic fluorinated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogs as potential probes in models of Parkinson disease. 1988 Apr 2
74 2884568 Evidence for neuromelanin involvement in MPTP-induced neurotoxicity. 1987 May 28-Jun 3 1
75 3108452 Overview of the present state of MAO inhibitors. 1987 1
76 3295117 Processing of MPTP by monoamine oxidases: implications for molecular toxicology. 1987 2
77 3305061 Immunohistochemical localization of monoamine oxidase-B in the cat brain: clues to understanding N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) toxicity. 1987 Sep 2
78 3315149 Antioxidant therapy in Parkinson's disease. 1987 Aug 1
79 3494215 Inhibition of type A monoamine oxidase by 1-methyl-4-phenylpyridine. 1987 Jan 27 2
80 3495757 Analogues of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine as monoamine oxidase substrates: a second ring is not necessary. 1987 May 19 4
81 3498665 Metabolic aspects of aging brain and related disorders. 1987 2
82 3556086 The significance of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. 1987 2
83 3083305 Monoamine oxidase B(MAO-B) is the major catalyst for 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) oxidation in human brain and other tissues. 1986 Feb 28 6
84 3091760 The actions of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in animals as a model of Parkinson's disease. 1986 2
85 3091762 The role of MAO in MPTP toxicity--a review. 1986 2
86 3097254 (-)Deprenyl in perspective: prophylaxis for Parkinson's disease? 1986 2
87 3485542 Studies on the mechanism of MPTP oxidation by human liver monoamine oxidase B. 1986 Apr 7 4
88 3485717 Interaction of monoamine oxidase B with analogues of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine derived from prodine-type analgesics. 1986 Apr 1
89 3486945 Monoamine oxidase B, smoking, and Parkinson's disease. 1986 Feb 4
90 3872126 Reversible inhibition and mechanism-based irreversible inactivation of monoamine oxidases by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). 1985 Mar 15 2
91 3874094 Metabolism of the neurotoxin in MPTP by human liver monoamine oxidase B. 1985 Jul 8 12
92 3875815 Conversion of the neurotoxic precursor 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine into its pyridinium metabolite by human platelet monoamine oxidase type B. 1985 Jun 24 3
93 6335034 Oxidation of the neurotoxic amine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by monoamine oxidases A and B and suicide inactivation of the enzymes by MPTP. 1984 Dec 14 2