Selegiline

monoamine oxidase B ; Homo sapiens







416 Article(s)
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51 27058977 High-throughput screening and radioligand binding studies reveal monoamine oxidase-B as the primary binding target for d-deprenyl. 2016 May 1 3
52 27061066 Rotigotine in Combination with the MAO-B Inhibitor Selegiline in Early Parkinson's Disease: A Post Hoc Analysis. 2016 Apr 2 1
53 27373997 Identification of Indole-Based Chalcones: Discovery of a Potent, Selective, and Reversible Class of MAO-B Inhibitors. 2016 Aug 1
54 24964753 DSP4, a selective neurotoxin for the locus coeruleus noradrenergic system. A review of its mode of action. 2015 Jan 1
55 25249059 Evidence that formulations of the selective MAO-B inhibitor, selegiline, which bypass first-pass metabolism, also inhibit MAO-A in the human brain. 2015 Feb 5
56 25514361 Rasagiline, a suicide inhibitor of monoamine oxidases, binds reversibly to α-synuclein. 2015 Feb 18 1
57 25532905 Potent and selective MAO-B inhibitory activity: amino- versus nitro-3-arylcoumarin derivatives. 2015 Feb 1 1
58 25572450 Response to Transdermal Selegiline Smoking Cessation Therapy and Markers in the 15q24 Chromosomal Region. 2015 Sep 1
59 25592412 An explorative study regarding the effect of l-deprenyl on cognitive and functional recovery in patients after stroke. 2015 Feb 15 2
60 25677185 Design and synthesis of a MAO-B-selectively activated prodrug based on MPTP: a mitochondria-targeting chemotherapeutic agent for treatment of human malignant gliomas. 2015 Apr 1
61 25863936 Rasagiline and selegiline suppress calcium efflux from mitochondria by PK11195-induced opening of mitochondrial permeability transition pore: a novel anti-apoptotic function for neuroprotection. 2015 Oct 1
62 26164425 Defining the Role of the Monoamine Oxidase-B Inhibitors for Parkinson's Disease. 2015 Jun 1
63 26189013 Development of fluorinated methoxylated chalcones as selective monoamine oxidase-B inhibitors: Synthesis, biochemistry and molecular docking studies. 2015 Oct 1
64 26337020 Synthesis of a series of unsaturated ketone derivatives as selective and reversible monoamine oxidase inhibitors. 2015 Oct 1 1
65 26352677 Novel 2H-chromen-2-one derivatives of resveratrol: Design, synthesis, modeling and use as human monoamine oxidase inhibitors. 2015 Oct 20 1
66 24769350 Polycyclic propargylamine and acetylene derivatives as multifunctional neuroprotective agents. 2014 Jun 10 1
67 24937131 The VMAT-2 inhibitor tetrabenazine affects effort-related decision making in a progressive ratio/chow feeding choice task: reversal with antidepressant drugs. 2014 1
68 22968599 Rasagiline and selegiline, inhibitors of type B monoamine oxidase, induce type A monoamine oxidase in human SH-SY5Y cells. 2013 Mar 2
69 23281824 Synthesis of (E)-8-(3-chlorostyryl)caffeine analogues leading to 9-deazaxanthine derivatives as dual A(2A) antagonists/MAO-B inhibitors. 2013 Feb 14 1
70 23328949 Synthesis, molecular modeling, and in vitro screening of monoamine oxidase inhibitory activities of some novel hydrazone derivatives. 2013 Jun 1
71 23410524 An update on amine oxidase inhibitors: multifaceted drugs. 2013 Jul 1 1
72 23420173 Interaction of selegiline-loaded PLGA-b-PEG nanoparticles with beta-amyloid fibrils. 2013 Jun 2
73 23474901 Novel (coumarin-3-yl)carbamates as selective MAO-B inhibitors: synthesis, in vitro and in vivo assays, theoretical evaluation of ADME properties and docking study. 2013 May 2
74 23506388 The pharmacokinetic evaluation of selegiline ODT for the treatment of Parkinson's disease. 2013 May 1
75 23611731 The opposite effect of isotype-selective monoamine oxidase inhibitors on adipogenesis in human bone marrow mesenchymal stem cells. 2013 Jun 1 1
76 23620664 Clinical significance of metallothioneins in cell therapy and nanomedicine. 2013 1
77 24005822 Selegiline reverses aβ₂₅₋₃₅-induced cognitive deficit in male mice. 2013 Nov 1
78 24012376 Development of a novel fluorine-18 labeled deuterated fluororasagiline ([(18)F]fluororasagiline-D2) radioligand for PET studies of monoamino oxidase B (MAO-B). 2013 Nov 1 2
79 24204150 Selegiline remarkably improved stage 5 treatment-resistant major depressive disorder: a case report. 2013 2
80 22065207 Type A monoamine oxidase is associated with induction of neuroprotective Bcl-2 by rasagiline, an inhibitor of type B monoamine oxidase. 2012 Apr 2
81 22086140 Basic cell physiological activities (cell adhesion, chemotaxis and proliferation) induced by selegiline and its derivatives in Mono Mac 6 human monocytes. 2012 May 2
82 22592509 Selegiline: a reappraisal of its role in Parkinson disease. 2012 May-Jun 1
83 22691758 Therapies in Parkinson's disease. 2012 Aug 1
84 22954444 Comparison of the cutaneous iontophoretic delivery of rasagiline and selegiline across porcine and human skin in vitro. 2012 Nov 15 1
85 23231395 Type A and B monoamine oxidase in age-related neurodegenerative disorders: their distinct roles in neuronal death and survival. 2012 2
86 21075154 Activated MAO-B in the brain of Alzheimer patients, demonstrated by [11C]-L-deprenyl using whole hemisphere autoradiography. 2011 Jan 5
87 21224199 Selegiline and rasagiline: twins or distant cousins? 2011 Jan 3
88 21423589 Efficacy, safety, and patient preference of monoamine oxidase B inhibitors in the treatment of Parkinson's disease. 2011 Jan 20 2
89 21626552 Milestones in Parkinson's disease therapeutics. 2011 May 1
90 21858609 Effects of selegiline, a monoamine oxidase B inhibitor, on differentiation of P19 embryonal carcinoma stem cells, into neuron-like cells. 2011 Sep 5
91 21923198 Synthesis of three novel fluorine-18 labeled analogues of L-deprenyl for positron emission tomography (PET) studies of monoamine oxidase B (MAO-B). 2011 Oct 27 4
92 21939547 Controversies in neurology: why monoamine oxidase B inhibitors could be a good choice for the initial treatment of Parkinson's disease. 2011 Sep 22 1
93 21971003 The pharmacology of selegiline. 2011 1
94 22110357 MAO-inhibitors in Parkinson's Disease. 2011 Mar 1
95 22133327 Monoamine oxidase B inhibitors for the treatment of Parkinson's disease: a review of symptomatic and potential disease-modifying effects. 2011 Dec 1 1
96 25205926 Cell based therapies in Parkinson's Disease. 2011 Apr 1
97 19939587 A double-blind, placebo-controlled, randomized clinical trial of oral selegiline hydrochloride for smoking cessation in nicotine-dependent cigarette smokers. 2010 Mar 1 4
98 20022592 A novel role for glyceraldehyde-3-phosphate dehydrogenase and monoamine oxidase B cascade in ethanol-induced cellular damage. 2010 May 1 2
99 20195940 [On the role of MAO B inhibitors and NMDA antagonists in the therapy of Parkinson's disease]. 2010 Mar 1
100 20644207 Changes in smoking expectancies in abstinent, reducing, and non-abstinent participants during a pharmacological trial for smoking cessation. 2010 Sep 1