Benzo(a)pyrene

cytochrome P450, family 2, subfamily g, polypeptide 1 ; Rattus norvegicus







63 Article(s)
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1 35437857 Protective role of AKBA against benzo(a)pyrene-induced lung carcinogenesis by modulating biotransformation enzymes and oxidative stress. 2022 Apr 19 1
2 28263535 Exposure of rats to exogenous endocrine disruptors 17alpha-ethinylestradiol and benzo(a)pyrene and an estrogenic hormone estradiol induces expression of cytochromes P450 involved in their metabolism. 2016 Dec 18 2
3 19889059 3-methylcholanthrene and benzo(a)pyrene modulate cardiac cytochrome P450 gene expression and arachidonic acid metabolism in male Sprague Dawley rats. 2009 Dec 1
4 21783461 Formation of estrogenic metabolites of benzo[a]pyrene and chrysene by cytochrome P450 activity and their combined and supra-maximal estrogenic activity. 2005 Jan 4
5 11588892 Monoclonal antibody-directed analysis of benzo[a]pyrene metabolism in rat liver and extrahepatic tissues: effect of propyl and octyl gallate. 2001 1
6 9555654 The cytochrome P-450 inhibitor cobalt chloride prevents inhibition of renal Na,K-ATPase and redistribution of apical NHE-3 during acute hypertension. 1998 Apr 2
7 1494976 Effect of carrageenan-induced inflammation on the induction of hepatic microsomal enzymes by phenobarbital and benzo[a]pyrene in male rats. 1992 Apr 1
8 1516151 Organ-selective induction of cytochrome P-450-dependent activities by indole-3-carbinol-derived products: influence on covalent binding of benzo[a]pyrene to hepatic and pulmonary DNA in the rat. 1992 Aug 28 1
9 1537398 Proton NMR study of the interaction of benzo(a)pyrene with rat liver microsomal cytochrome P-450. 1992 Jan 27 3
10 1654602 Alterations of pulmonary benzo[a]pyrene metabolism by reactive oxygen metabolites. 1991 1
11 1654904 NADPH-dependent reduction of amaranch in liver microsomes characterized the quantity of low spin forms of cytochrome P-450. 1991 Sep 16 1
12 1759389 [Cytochrome P-450 activity and lipid peroxidation in rat liver and lung microsomes during hypoxia and followed by pressure oxygenation]. 1991 Sep-Oct 2
13 1913623 Effects of synthetic and naturally occurring flavonoids on benzo[a]pyrene metabolism by hepatic microsomes prepared from rats treated with cytochrome P-450 inducers. 1991 Oct 1
14 2072980 Monoclonal antibody characterization of NADH- and NADPH-dependent hydroxylation of benzo(a)pyrene in liver microsomes from 5,6-benzoflavone-induced C57Bl/6 mice. 1990 1
15 2107605 A time course investigation of vitamin A level and lipid composition of the liver endoplasmic reticulum in rats following treatment with congeneric polychlorobiphenyls. 1990 Mar 16 1
16 2125771 Induction of drug-metabolizing enzymes by xenobiotics. 1990 Nov 1
17 2328803 [Cytochrome P-450 induction and the subsequent induction of an immune response in rats during the chronic administration of xenobiotics]. 1990 Jan-Feb 2
18 2343577 [The role of secondary metabolism in formation of benz(a)pyrene dihydrodiol profile in microsome membranes]. 1990 Jan-Feb 1
19 2364062 Binding of benzo[a]pyrene to DNA by cytochrome P-450 catalyzed one-electron oxidation in rat liver microsomes and nuclei. 1990 May 22 4
20 2495007 Differential effects of cyclosporin on hepatic and renal heme, cytochrome P-450 and drug metabolism. Possible role in nephrotoxicity of the drug. 1989 Mar 15 1
21 2498299 Purification and properties of cytochrome P-450 generally acting as a catalyst on benzo[a]pyrene hydroxylation from liver microsomes of untreated rats. 1989 Feb 2
22 2844763 Purification and characterization of vitamin D 25-hydroxylase from rat liver mitochondria. 1988 Oct 5 1
23 3142693 Benzo[a]pyrene metabolism and induction of enzyme-altered foci in regenerating rat liver. 1988 2
24 3172284 Effects of p-tert-butylphenyl trans-4-guanidinomethylcyclohexane carboxylate hydrochloride (NCO-650) and its metabolite, p-tert-butylphenol(BP) on drug-metabolizing enzymes and fine structure in rat liver. 1988 May 1
25 3181598 The effect of selenium on the hepatic drug metabolism and inducibility in rat. 1988 1
26 3335509 Hepatic mitochondrial cytochrome P-450 system. Identification and characterization of a precursor form of mitochondrial cytochrome P-450 induced by 3-methylcholanthrene. 1988 Jan 5 1
27 3498153 BP metabolism and the in vivo binding to hepatic DNA of rats fed diets containing menhaden fish oil. 1987 1
28 3579981 Binding of reactive metabolites of CCl4 to specific microsomal proteins. 1987 May 1 1
29 2423085 Resorufin inhibits the in vitro metabolism and mutagenesis of benzo(a)pyrene. 1986 Apr 29 1
30 3707619 Dependence of benzo[a]pyrene metabolic profile on the concentration of cumene hydroperoxide with uninduced and induced rat liver microsomes. 1986 May 1 3
31 2866028 Activities of drug-metabolizing enzymes in isolated gamma-glutamyltranspeptidase positive preneoplastic hepatocytes from carcinogen treated rats. 1985 Oct 1
32 3839642 Cytochrome P-450-catalyzed stereoselective epoxidation at the K region of benz[a]anthracene and benzo[a]pyrene. 1985 Aug 1 2
33 3875401 Metabolism of benzo(a)pyrene by subcellular fractions of rat liver: evidence for similar patterns of cytochrome P-450 in rough and smooth endoplasmic reticulum but not in nuclei and plasma membrane. 1985 Oct 2
34 3928617 Purification and characterization of seven distinct forms of liver microsomal cytochrome P-450 from untreated and inducer-treated male Wistar rats. 1985 Jun 1
35 4070009 Vitamin A status and metabolism of benzo[a]pyrene in the rat. 1985 2
36 4085395 [Specificity of cytochrome P-450 isoforms contained in endoplasmic reticulum membranes and nuclear membranes in relation to benzo(a)pyrene]. 1985 2
37 6089701 Phthalate esters. II. Effects of inhaled dibutylphthalate on cytochrome P-450 mediated metabolism in rat liver and lung. 1984 Jul 1
38 6326392 The mechanistic plurality of cytochrome P-450 and its biological ramifications. 1984 Jan-Feb 1
39 6327095 Covalent binding of benzo[a]pyrene to cytochrome P-450 beta NF-B2 and other proteins in reconstituted mixed-function oxidase systems. 1984 May 4
40 6430544 Participation of cytochrome P-450 in reductive metabolism of 1-nitropyrene by rat liver microsomes. 1984 Aug 1
41 6435901 Binding and metabolism of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene by seven purified forms of cytochrome P-450. 1984 Nov 3
42 6436235 Hepatic mitochondrial cytochrome P-450 system. Distinctive features of cytochrome P-450 involved in the activation of aflatoxin B1 and benzo(a)pyrene. 1984 Oct 25 1
43 6487578 1-Ethynylpyrene, a suicide inhibitor of cytochrome P-450 dependent benzo[a]pyrene hydroxylase activity in liver microsomes. 1984 Aug 14 1
44 6487785 [Hydroxylation products of hydrophobic xenobiotics--stabilizers of cytochrome P-450 in the hepatocytes]. 1984 Sep 1
45 6295661 Specificity of rat liver cytochrome P-450 isozymes in the mutagenic activation of benzo[a]pyrene, aromatic amines and aflatoxin B1. 1983 1
46 6303564 Prostaglandin synthetase and cytochrome P-450-dependent metabolism of (+/-)benzo(a)pyrene 7,8-dihydrodiol by enriched populations of rat Clara cells and alveolar type II cells. 1983 Jun 1
47 6305488 Immunochemical study on the contributions of two molecular species of microsomal cytochrome P-450 to the metabolism of benzo(a)pyrene by rat liver microsomes. 1983 Aug 2
48 6314905 Differential metabolism of acetanilide versus ethoxycoumarin and benzo[a]pyrene by two 3-methylcholanthrene-inducible forms of rat liver cytochrome P-450. 1983 Oct 15 1
49 6622818 Differential properties of the microsomal deamination and hydroxylation reactions. 1983 Jun 2
50 6830852 Partial inhibition of hepatic microsomal aminopyrine N-demethylase by caffeine in partially purified cytochrome P450. 1983 Mar 31 1