gamma-Aminobutyric Acid

4-aminobutyrate aminotransferase ; Rattus norvegicus







125 Article(s)
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1 34617595 OV329, a novel highly potent γ-aminobutyric acid aminotransferase inactivator, induces pronounced anticonvulsant effects in the pentylenetetrazole seizure threshold test and in amygdala-kindled rats. 2021 Dec 2
2 32453018 Waggle needling wields preferable neuroprotective and anti-spastic effects on post-stroke spasticity rats by attenuating γ-aminobutyric acid transaminase and enhancing γ-aminobutyric acid. 2020 Jul 10 1
3 32526640 Immediate versus late effects of vigabatrin on spike and wave discharges. 2020 Sep 1
4 31419724 PKA-mediated phosphorylation of CREB and NMDA receptor 2B in the hippocampus of offspring rats is involved in transmission of mental disorders across a generation. 2019 Oct 1
5 27678549 Neurobehavioral effects of vigabatrin and its ability to induce DNA damage in brain cells after acute treatment in rats. 2017 Jan 1
6 26608704 A study on the involvement of GABA-transaminase in MCT induced pulmonary hypertension. 2016 Feb 1
7 26976738 Continuous bilateral infusion of vigabatrin into the subthalamic nucleus: Effects on seizure threshold and GABA metabolism in two rat models. 2016 Jul 2
8 20878340 Effects of GABA-transaminase inhibitor Vigabatrin on thermoregulation in rats. 2011 May 2
9 20033132 Gamma-vinyl GABA increases nonvesicular release of GABA and glutamate in the nucleus accumbens in rats via action on anion channels and GABA transporters. 2010 Mar 1
10 17190904 Glucagon-like peptide-1 stimulates GABA formation by pancreatic beta-cells at the level of glutamate decarboxylase. 2007 Apr 3
11 16517019 Acute regulation of steady-state GABA levels following GABA-transaminase inhibition in rat cerebral cortex. 2006 May-Jun 1
12 16539672 Evidence that GAD65 mediates increased GABA synthesis during intense neuronal activity in vivo. 2006 Apr 1
13 15619231 Elevated endogenous GABA level correlates with decreased fMRI signals in the rat brain during acute inhibition of GABA transaminase. 2005 Feb 1 2
14 15912138 Anticonvulsant enaminones depress excitatory synaptic transmission in the rat brain by enhancing extracellular GABA levels. 2005 Aug 1
15 15927473 Design and biological evaluation of phenyl-substituted analogs of beta-phenylethylidenehydrazine. 2005 Jul 15 1
16 15207360 Phenylethylidenehydrazine, a novel GABA-transaminase inhibitor, reduces epileptiform activity in rat hippocampal slices. 2004 2
17 15304357 Purification and expression of a processing protease on beta-alanine-oxoglutarate aminotransferase from rat liver mitochondria. 2004 Aug 13 1
18 12509804 Gabaergic signaling mediates the morphological organization of astrocytes in the adult rat forebrain. 2003 Jan 15 1
19 12581825 The effects of vigabatrin on type II spike wave discharges in rats. 2003 Mar 6 1
20 12200213 Effects of vigabatrin on epileptiform abnormal discharges in hippocampal CA3 neurons of spontaneously epileptic rats (SER). 2002 Aug 1
21 11459221 Comparative studies on the GABA-transaminase immunoreactivity in rat and gerbil brains. 2001 Jun 30 2
22 11520491 Effects of radiofrequency exposure on the GABAergic system in the rat cerebellum: clues from semi-quantitative immunohistochemistry. 2001 Aug 31 1
23 11533137 Plasticity of rat central inhibitory synapses through GABA metabolism. 2001 Sep 1 4
24 11578600 Decrease in GABA synthesis rate in rat cortex following GABA-transaminase inhibition correlates with the decrease in GAD(67) protein. 2001 Sep 28 1
25 11701133 Glutamine is the major precursor for GABA synthesis in rat neocortex in vivo following acute GABA-transaminase inhibition. 2001 Nov 23 1
26 11775064 Effects of the antidepressant/antipanic drug phenelzine on alanine and alanine transaminase in rat brain. 2001 Aug 3
27 10665820 Reversal of the activity-dependent suppression of GABA-mediated inhibition in hippocampal slices from gamma-vinyl GABA (vigabatrin)-pretreated rats. 2000 1
28 10727784 Glutamate dependence of GABA levels in neurons of hypoxic and hypoglycemic rat hippocampal slices. 2000 1
29 11027398 Immunohistochemical studies of the localization of neurons containing the enzyme that synthesizes dopamine, GABA, or gamma-hydroxybutyrate in the rat substantia nigra and striatum. 2000 Oct 30 1
30 11198049 Evidence that long-lasting potentiation of amygdala efferents in the right hemisphere underlies pharmacological stressor (FG-7142) induced lasting increases in anxiety-like behaviour: role of GABA tone in initiation of brain and behavioural changes. 2000 1
31 10206175 Effects of increasing doses of vigabatrin on platelet gamma-aminobutyric acid-transaminase and brain gamma-aminobutyric acid in rats. 1999 Mar 19 3
32 10375453 Changes of GABA metabolic enzymes in acute retinal ischemia. 1999 Jul 1
33 10411594 The irreversible gamma-aminobutyric acid (GABA) transaminase inhibitor gamma-vinyl-GABA blocks cocaine self-administration in rats. 1999 Aug 1
34 10448817 Time course of the GABAergic effects of vigabatrin: is the time course of brain GABA related to platelet GABA-transaminase inhibition? 1999 Aug 4
35 9551781 Vigabatrin enhances promoted release of GABA in neonatal rat optic nerve. 1998 Feb 2
36 9669322 Elevation of brain GABA levels with vigabatrin (gamma-vinylGABA) differentially affects GAD65 and GAD67 expression in various regions of rat brain. 1998 Jun 15 2
37 9719948 Effects of iron deficiency on iron distribution and gamma-aminobutyric acid (GABA) metabolism in young rat brain tissues. 1998 May 2
38 9754804 Localization of GABA transaminase immunoreactivity in the rat substantia nigra pars reticulata. 1998 Aug 28 1
39 10098727 Expression of GABA transaminase immunoreactivity in interneurons of the rat neostriatum. 1998 Dec 1
40 9088880 Basic aspects of GABA-transmission in alcoholism, with particular reference to GABA-transaminase. 1997 Feb 2
41 9351512 Effect of chronic treatment with the GABA transaminase inhibitors gamma-vinyl GABA and ethanolamine O-sulphate on the in vitro GABA release from rat hippocampus. 1997 Oct 4
42 9372539 Gamma-vinyl GABA attenuates cocaine-induced lowering of brain stimulation reward thresholds. 1997 Oct 2
43 26735441 Brain GABA metabolism after chronic ethanol consumption and withdrawal in rats. 1997 Jan 3
44 8762104 Presynaptic modulation by L-glutamate and GABA of sympathetic co-transmission in rat isolated vas deferens. 1996 Jun 1
45 8867039 In vivo regulation of specific GABAA receptor subunit messenger RNAs by increased GABA concentrations in rat brain. 1996 Apr 1
46 8911659 The novel antiepileptic drug levetiracetam (ucb L059) induces alterations in GABA metabolism and turnover in discrete areas of rat brain and reduces neuronal activity in substantia nigra pars reticulata. 1996 Oct 7 1
47 8931464 Regulation of GABA level in rat brain synaptosomes: fluxes through enzymes of the GABA shunt and effects of glutamate, calcium, and ketone bodies. 1996 Dec 2
48 8937445 Effects of chronic oral treatment with GABA-transaminase inhibitors on the GABA system in brain, liver, kidney, and plasma of the rat. 1996 Nov 8 4
49 8788866 Effect of the GABA-transaminase inhibitor vigabatrin on exploratory behaviour in socially isolated rats. 1995 Dec 14 7
50 7914662 Measurement of GABA following GABA-transaminase inhibition by gabaculine: a 1H and 31P NMR spectroscopic study of rat brain in vivo. 1994 Jun 1