Tyrosine

C-terminal Src kinase ; Homo sapiens







128 Article(s)
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1 35059869 The inhibition of Panc1 cancer cells invasion by hAMSCs secretome through suppression of tyrosine phosphorylation of SGK223 (at Y411 site), c-Src (at Y416, Y530 sites), AKT activity, and JAK1/Stat3 signaling. 2022 Jan 20 1
2 35393453 SH3-domain mutations selectively disrupt Csk homodimerization or PTPN22 binding. 2022 Apr 7 1
3 32794043 The role of competing mechanisms on Lck regulation. 2020 Oct 1
4 29503074 Dimerization of the Pragmin Pseudo-Kinase Regulates Protein Tyrosine Phosphorylation. 2018 Apr 3 1
5 29723216 c-Src kinase is involved in the tyrosine phosphorylation and activity of SLC11A1 in differentiating macrophages. 2018 2
6 30100205 Positive regulatory role of c-Src-mediated TRIM25 tyrosine phosphorylation on RIG-I ubiquitination and RIG-I-mediated antiviral signaling pathway. 2018 Oct 1
7 28784162 Csk-homologous kinase (Chk) is an efficient inhibitor of Src-family kinases but a poor catalyst of phosphorylation of their C-terminal regulatory tyrosine. 2017 Aug 7 1
8 26527736 Structural basis for the regulatory role of the PPxY motifs in the thioredoxin-interacting protein TXNIP. 2016 Jan 15 2
9 26755576 Gain-of-function mutations of Ptpn11 (Shp2) cause aberrant mitosis and increase susceptibility to DNA damage-induced malignancies. 2016 Jan 26 1
10 26996624 Phosphorylation Processes Controlling Aromatase Activity in Br east Cancer: An Update. 2016 1
11 27116701 C-terminal Src kinase-mediated EPIYA phosphorylation of Pragmin creates a feed-forward C-terminal Src kinase activation loop that promotes cell motility. 2016 Jul 2
12 27391443 Connexin43 recruits PTEN and Csk to inhibit c-Src activity in glioma cells and astrocytes. 2016 Aug 2 2
13 25376742 A Discovery Strategy for Selective Inhibitors of c-Src in Complex with the Focal Adhesion Kinase SH3/SH2-binding Region. 2015 Aug 1
14 25897081 Protein-tyrosine Phosphatase and Kinase Specificity in Regulation of SRC and Breast Tumor Kinase. 2015 Jun 26 1
15 26234813 Csk-Induced Phosphorylation of Src at Tyrosine 530 is Essential for H2O2-Mediated Suppression of ERK1/2 in Human Umbilical Vein Endothelial Cells. 2015 Aug 3 2
16 26304753 Role of phosphatase activity of soluble epoxide hydrolase in regulating simvastatin-activated endothelial nitric oxide synthase. 2015 Aug 25 1
17 24300854 Junctional adhesion molecule-A suppresses platelet integrin αIIbβ3 signaling by recruiting Csk to the integrin-c-Src complex. 2014 Feb 27 4
18 24405902 Downregulation of inhibitory SRC homology 2 domain-containing phosphatase-1 (SHP-1) leads to recovery of T cell responses in elderly. 2014 Jan 9 2
19 24632723 SHP-2 binds to caveolin-1 and regulates Src activity via competitive inhibition of CSK in response to H2O2 in astrocytes. 2014 3
20 24902122 The Haemophilus ducreyi LspA1 protein inhibits phagocytosis by using a new mechanism involving activation of C-terminal Src kinase. 2014 May 20 1
21 25292214 Tyrosine phosphorylation of NEDD4 activates its ubiquitin ligase activity. 2014 Oct 7 1
22 23333462 The dioxin receptor controls β1 integrin activation in fibroblasts through a Cbp-Csk-Src pathway. 2013 Apr 3
23 23471971 Increased activity of the vesicular soluble N-ethylmaleimide-sensitive factor attachment protein receptor TI-VAMP/VAMP7 by tyrosine phosphorylation in the Longin domain. 2013 Apr 26 1
24 22544307 PTPIP51 in protein interactions: regulation and in situ interacting partners. 2012 Jul 1
25 22962253 Estrogens and PTP1B function in a novel pathway to regulate aromatase enzymatic activity in breast cancer cells. 2012 Nov 1
26 21113815 The NMDA receptor NR1 subunit is critically involved in the regulation of NMDA receptor activity by C-terminal Src kinase (Csk). 2011 Feb 1
27 21873224 Mammalian Pragmin regulates Src family kinases via the Glu-Pro-Ile-Tyr-Ala (EPIYA) motif that is exploited by bacterial effectors. 2011 Sep 6 1
28 19818398 Tyrosine 170 is dispensable for c-Jun turnover. 2010 Feb 1
29 20048167 Src-induced tyrosine phosphorylation of VE-cadherin is not sufficient to decrease barrier function of endothelial monolayers. 2010 Mar 5 1
30 20346773 CD45-Csk phosphatase-kinase titration uncouples basal and inducible T cell receptor signaling during thymic development. 2010 Mar 26 1
31 20457609 Tyrosine residues at the carboxyl terminus of Vav1 play an important role in regulation of its biological activity. 2010 Jul 23 1
32 19632164 Identification of c-Src tyrosine kinase substrates in platelet-derived growth factor receptor signaling. 2009 Dec 1
33 19808673 Differential effects of lysophosphatidic acid and phosphatidylinositol 4,5-bisphosphate on actin dynamics by direct association with the actin-binding protein villin. 2009 Dec 18 1
34 18085663 A displaced PAG enhances proximal signaling and SDF-1-induced T cell migration. 2008 Jan 2
35 18086565 Proteomic identification of ZO-1/2 as a novel scaffold for Src/Csk regulatory circuit. 2008 Feb 22 1
36 18451158 Met and c-Src cooperate to compensate for loss of epidermal growth factor receptor kinase activity in breast cancer cells. 2008 May 1 3
37 18614016 Structural basis for the recognition of c-Src by its inactivator Csk. 2008 Jul 11 4
38 18644992 Antiproliferative effect of sulindac in colonic neoplasia prevention: role of COOH-terminal Src kinase. 2008 Jul 1
39 18783823 PP2 regulates human trophoblast cells differentiation by activating p38 and ERK1/2 and inhibiting FAK activation. 2008 Oct 2
40 17233630 Paxillin family members function as Csk-binding proteins that regulate Lyn activity in human and murine platelets. 2007 Apr 15 4
41 17389760 A novel negative regulatory function of the phosphoprotein associated with glycosphingolipid-enriched microdomains: blocking Ras activation. 2007 Jul 15 1
42 17691821 Subdomain switching reveals regions that harbor substrate specificity and regulatory properties of protein tyrosine kinases. 2007 Sep 4 1
43 17897955 A weak Lck tail bite is necessary for Lck function in T cell antigen receptor signaling. 2007 Dec 7 1
44 16289966 Activation of Epstein-Barr virus/C3d receptor (gp140, CR2, CD21) on human B lymphoma cell surface triggers Cbl tyrosine phosphorylation, its association with p85 subunit, Crk-L and Syk and its dissociation with Vav. 2006 Aug 1
45 16439366 Docking-based substrate recognition by the catalytic domain of a protein tyrosine kinase, C-terminal Src kinase (Csk). 2006 Mar 24 2
46 16765913 A new strategy to produce active human Src from bacteria for biochemical study of its regulation. 2006 Jul 28 1
47 16959780 C-terminal Src kinase-homologous kinase (CHK), a unique inhibitor inactivating multiple active conformations of Src family tyrosine kinases. 2006 Nov 3 2
48 17018524 SRC tail phosphorylation is limited by structural changes in the regulatory tyrosine kinase Csk. 2006 Dec 8 1
49 17149882 Design and evaluation of hydroxamate derivatives as metal-mediated inhibitors of a protein tyrosine kinase. 2006 Dec 14 1
50 15637072 Involvement of c-Src and protein kinase C delta in the inhibition of Cl(-)/OH- exchange activity in Caco-2 cells by serotonin. 2005 Mar 25 1