Benzo(a)pyrene

cytochrome P450, family 1, subfamily a, polypeptide 1 ; Rattus norvegicus







89 Article(s)
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51 1316759 Induction of CYP1A1 gene expression in H4-II-E rat hepatoma cells by benzo[e]pyrene. 1992 2
52 1800893 The use of genetically engineered V79 Chinese hamster cultures expressing rat liver CYP1A1, 1A2 and 2B1 cDNAs in micronucleus assays. 1991 Nov 1
53 1871778 The effect of toluene on rat lung benzo[a]pyrene metabolism and microsomal membrane lipids. 1991 4
54 1985961 Interactions among cytochromes P-450 in the endoplasmic reticulum. Detection of chemically cross-linked complexes with monoclonal antibodies. 1991 Jan 15 1
55 2799823 The effect of m-xylene on rat lung benzo[a]pyrene metabolism and microsomal membrane lipids: comparison with p-xylene. 1989 Oct 2 2
56 2837492 Hepatic mitochondrial cytochrome P-450 system. Purification and characterization of two distinct forms of mitochondrial cytochrome P-450 from beta-naphthoflavone-induced rat liver. 1988 Jul 5 2
57 3181598 The effect of selenium on the hepatic drug metabolism and inducibility in rat. 1988 1
58 3293833 The 4S binding protein acts as a trans-regulator of the polycyclic hydrocarbon-inducible cytochrome P450. 1988 Apr 2
59 3402044 Role of the 4-5S binding protein in the induction of aryl hydrocarbon hydroxylase in the rat. 1988 Aug 1
60 3103934 Product inhibition of benzo[a]pyrene metabolism in uninduced rat liver microsomes: effect of diol epoxide formation. 1987 Feb 3
61 3564534 Benzo[a]pyrene metabolism by purified cytochrome P-450 from 3-methylcholanthrene-treated rats. 1987 Feb 1
62 3660849 Inhibition of cytochrome P-450c-mediated benzo[a]pyrene hydroxylase and ethoxyresorufin O-deethylase by dihydrosafrole. 1987 Jul 2
63 2428858 Induction of aryl hydrocarbon hydroxylase in rat tissue following intratracheal instillation of diesel particulate extract and benzo[a]pyrene. 1986 Aug 1
64 3096979 Pulmonary microsomal cytochrome P-450 from 3-methylcholanthrene-treated hamsters: purification, characterization, and metabolism of benzo(a)pyrene. 1986 Aug 5
65 3758464 Induction and catalytic activities of cytochromes P-450b/e and P-450c in the liver microsomes of neonatal rats. 1986 1
66 3900057 Characterization of rat cytochrome P-450MC synthesized in Saccharomyces cerevisiae. 1985 Jul 1
67 3995102 [Isolation and characterization of multiple forms of cytochrome P-450 from liver microsomes of 3-methylcholanthrene-induced Wistar rats]. 1985 Mar 2
68 4074682 Binding of benzo[a]pyrene by purified cytochrome P-450c. 1985 Sep 10 4
69 4074683 Selectivity in the binding of hydroxylated benzo[a]pyrene derivatives to purified cytochrome P-450c. 1985 Sep 10 7
70 6438082 Benzo(a)pyrene activation to 7,8-dihydrodiol 9,10-oxide by rat liver microsomes. Control by selective product inhibition. 1984 Nov 25 2
71 6309378 Some biotransformation enzymes responsible for polycyclic aromatic hydrocarbon metabolism in rat nasal turbinates: effects on enzyme activities of in vitro modifiers and intraperitoneal and inhalation exposure of rats to inducing agents. 1983 Oct 1
72 6315393 Lung aryl hydrocarbon hydroxylase: inhibition following cadmium chloride inhalation. 1983 Dec 2
73 6885735 Purification and characterization of pulmonary cytochrome P-450 from 3-methylcholanthrene-treated rats. 1983 Jun 3
74 6286155 Structure-activity relationships of chlorinated benzenes as inducers of different forms of cytochrome P-450 in rat liver. 1982 Aug 2
75 7057055 Induction of neonatal rat skin and liver aryl hydrocarbon hydroxylase by coal tar and its constituents. 1982 Mar 2
76 6114828 Drug metabolism in skin. Comparative activity of the mixed-function oxidases, epoxide hydratase, and glutathione S-transferase in liver and skin of the neonatal rat. 1981 Jul-Aug 2
77 6275873 Ontogenetic variation in rat liver, lung and kidney monooxygenase induction by low doses of benzo(A)pyrene and cigarette-smoke condensate. 1981 Dec 1
78 7198004 Sex dependent effect of chronic ethanol consumption in rats on hepatic microsome mediated mutagenicity of benzo[a]pyrene. 1981 Jul 1
79 6930944 Dose-response relationship of rat aryl hydrocarbon hydroxylase and epoxide hydratase induction. 1980 1
80 7417608 Effects of perinatal exposure to benzo(a)pyrene on the aryl hydrocarbon hydroxylase system of adult rat liver. 1980 1
81 227145 Increased aryl hydrocarbon hydroxylase and prolyl hydroxylase activities in lung organ cultures exposed to benzo[a]pyrene. 1979 Mar-Apr 5
82 549739 Benzo[a]pyrene metabolism in rat fetal hepatocytes culture. Improved methodology and effect of substrate concentration. 1979 Dec 1
83 98453 Stimulatory effect of cigarette smoke on the metabolism and covalent binding of benzo(a)pyrene in the trachea of the rat. 1978 Jul 15 1
84 106613 [Action of polychlorinated biphenyls (Kanechlor 500 and Delor 106) and 3-methylcholanthrene on the activity of some rat liver microsomal enzymes]. 1978 1
85 856463 Influence of inducers and inhibitors of mixed-function oxidasts on benzo(a)pyrene binding to the DNA of rat liver nuclei. 1977 May 1
86 912816 Effect of various chemicals on the metabolism of benzo(a)pyrene by cultured rat colon. 1977 Sep 1
87 10077 Formation in isolated rat liver microsomes and nuclei of benzo(a)pyrene metabolites that bind to DNA. 1976 Nov 4
88 182361 Binding of metabolically activated benzo(a)pyrene to nuclear macromolecules. 1976 Oct 1
89 944582 Effect of benzo(a)pyrene and chlorpromazine on aryl hydrocarbon hydroxylase activity from rat tissues. 1976 Apr 15 1