150 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 34464807 | Comparison of recovery characteristics between AnAOB and AOB-AnAOB granular sludge after long-term storage. | 2022 Jan 1 | 1 |
2 | 34953855 | The antimicrobial drug pyrimethamine inhibits STAT3 transcriptional activity by targeting the enzyme dihydrofolate reductase. | 2022 Feb | 5 |
3 | 35253073 | Dihydrofolate reductase, thymidylate synthase, and serine hydroxy methyltransferase: successful targets against some infectious diseases. | 2022 Mar 7 | 1 |
4 | 32820034 | CIC de novo loss of function variants contribute to cerebral folate deficiency by downregulating FOLR1 expression. | 2021 Jul | 2 |
5 | 33904374 | Identification of selective LdDHFR inhibitors using quantum chemical and molecular modeling approach. | 2021 Apr 27 | 1 |
6 | 34412467 | Targeted Mitochondrial Fluorescence Imaging-Guided Tumor Antimetabolic Therapy with the Imprinted Polymer Nanomedicine Capable of Specifically Recognizing Dihydrofolate Reductase. | 2021 Sep 1 | 2 |
7 | 34710812 | Computational algorithmic and molecular dynamics study of functional and structural impacts of non-synonymous single nucleotide polymorphisms in human DHFR gene. | 2021 Dec | 2 |
8 | 34825630 | 3D-QSAR, molecular docking, DFT and ADMET studies on quinazoline derivatives to explore novel DHFR inhibitors. | 2021 Nov 26 | 2 |
9 | 34829516 | CRIF1 Deficiency Increased Homocysteine Production by Disrupting Dihydrofolate Reductase Expression in Vascular Endothelial Cells. | 2021 Oct 20 | 2 |
10 | 32319147 | Significant association between DHFR promoter methylation and ischemic stroke in a Chinese hypertensive population. | 2020 Aug | 1 |
11 | 32498709 | Low folate intake and serum levels are associated with higher body mass index and abdominal fat accumulation: a case control study. | 2020 Jun 4 | 3 |
12 | 32752079 | In Silico Study Identified Methotrexate Analog as Potential Inhibitor of Drug Resistant Human Dihydrofolate Reductase for Cancer Therapeutics. | 2020 Jul 31 | 2 |
13 | 31058257 | NADPH production by the oxidative pentose-phosphate pathway supports folate metabolism. | 2019 Mar | 1 |
14 | 31401334 | Expression and Role of Methylenetetrahydrofolate Dehydrogenase 1 Like (MTHFD1L) in Bladder Cancer. | 2019 Nov | 1 |
15 | 31443485 | Maternal Haplotypes in DHFR Promoter and MTHFR Gene in Tuning Childhood Acute Lymphoblastic Leukemia Onset-Latency: Genetic/Epigenetic Mother/Child Dyad Study (GEMCDS). | 2019 Aug 22 | 1 |
16 | 31542479 | DHFR/TYMS are positive regulators of glioma cell growth and modulate chemo-sensitivity to temozolomide. | 2019 Nov 15 | 2 |
17 | 31920364 | Evaluation of Hematological Parameters in the Genetic Prospective in Epileptic Patients of Khyber Pakhtunkhwa. | 2019 | 1 |
18 | 29321536 | Enzymes of the one-carbon folate metabolism as anticancer targets predicted by survival rate analysis. | 2018 Jan 10 | 1 |
19 | 29708443 | Maternal association and influence of DHFR 19 bp deletion variant predisposes foetus to anencephaly susceptibility: a family-based triad study. | 2018 Nov | 2 |
20 | 30120883 | Association of FOLH1, DHFR, and MTHFR gene polymorphisms with susceptibility of Neural Tube Defects: A case control study from Eastern India. | 2018 Aug 15 | 2 |
21 | 28188287 | A-to-I RNA Editing Up-regulates Human Dihydrofolate Reductase in Breast Cancer. | 2017 Mar 24 | 1 |
22 | 28338744 | Understanding the molecular mechanism of substrate channeling and domain communication in protozoal bifunctional TS-DHFR. | 2017 Mar 1 | 3 |
23 | 28496133 | Folate Metabolism Regulates Oligodendrocyte Survival and Differentiation by Modulating AMPKα Activity. | 2017 May 11 | 4 |
24 | 28939533 | Comparative mapping of on-targets and off-targets for the discovery of anti-trypanosomatid folate pathway inhibitors. | 2017 Dec | 2 |
25 | 28939595 | Dihydrofolate Reductase/Thymidylate Synthase Fine-Tunes the Folate Status and Controls Redox Homeostasis in Plants. | 2017 Nov | 4 |
26 | 26229988 | Naked-eye nanobiosensor for therapeutic drug monitoring of methotrexate. | 2016 Jan 21 | 2 |
27 | 26881719 | Repositioning of DHFR Inhibitors. | 2016 | 1 |
28 | 26929741 | Non-DHFR-mediated effects of methotrexate in osteosarcoma cell lines: epigenetic alterations and enhanced cell differentiation. | 2016 | 2 |
29 | 27013776 | Down-regulation of dihydrofolate reductase inhibits the growth of endothelial EA.hy926 cell through induction of G1 cell cycle arrest via up-regulating p53 and p21(waf1/cip1) expression. | 2016 Mar | 1 |
30 | 27064332 | Assessment of Folic Acid Supplementation in Pregnant Women by Estimation of Serum Levels of Tetrahydrofolic Acid, Dihydrofolate Reductase, and Homocysteine. | 2016 | 1 |
31 | 27131640 | Excessive folic acid intake and relation to adverse health outcome. | 2016 Jul | 1 |
32 | 27189223 | Site specific polarization transfer from a hyperpolarized ligand of dihydrofolate reductase. | 2016 May | 2 |
33 | 27213086 | Structural Exploration and Conformational Transitions in MDM2 upon DHFR Interaction from Homo sapiens: A Computational Outlook for Malignancy via Epigenetic Disruption. | 2016 | 1 |
34 | 27919952 | Molecular Factors Associated with Pemetrexed Sensitivity According to Histological Type in Non-small Cell Lung Cancer. | 2016 Dec | 1 |
35 | 27994750 | Discovery of Potent and Selective Leads against Toxoplasma gondii Dihydrofolate Reductase via Structure-Based Design. | 2016 Dec 8 | 1 |
36 | 25315410 | A novel antibiotic-delivery system by using ovotransferrin as targeting molecule. | 2015 Jan 23 | 2 |
37 | 25441416 | Miniature multi-channel SPR instrument for methotrexate monitoring in clinical samples. | 2015 Feb 15 | 1 |
38 | 26022931 | New small-molecule inhibitors of dihydrofolate reductase inhibit Streptococcus mutans. | 2015 Aug | 1 |
39 | 26131691 | Methotrexate Is a JAK/STAT Pathway Inhibitor. | 2015 | 1 |
40 | 26144049 | The role of folate metabolism in orofacial development and clefting. | 2015 Sep 1 | 1 |
41 | 26269242 | The Dihydrofolate Reductase 19 bp Polymorphism Is Not Associated with Biomarkers of Folate Status in Healthy Young Adults, Irrespective of Folic Acid Intake. | 2015 Oct | 3 |
42 | 26354538 | Dihydrofolate reductase 19-bp deletion polymorphism modifies the association of folate status with memory in a cross-sectional multi-ethnic study of adults. | 2015 Nov | 4 |
43 | 26414244 | Folic Acid Promotes Recycling of Tetrahydrobiopterin and Protects Against Hypoxia-Induced Pulmonary Hypertension by Recoupling Endothelial Nitric Oxide Synthase. | 2015 Nov 10 | 1 |
44 | 26875486 | Gene-Nutrient Interaction between Folate and Dihydrofolate Reductase in Risk for Adenomatous Polyp Occurrence: A Preliminary Report. | 2015 | 5 |
45 | 24705454 | Influence of the Debye length on the interaction of a small molecule-modified Au nanoparticle with a surface-bound bioreceptor. | 2014 May 18 | 3 |
46 | 24739308 | Origin of robustness in generating drug-resistant malaria parasites. | 2014 Jul | 1 |
47 | 27025730 | Utility of the Biosynthetic Folate Pathway for Targets in Antimicrobial Discovery. | 2014 Jan 21 | 3 |
48 | 23421317 | DHFR 19-bp deletion and SHMT C1420T polymorphisms and metabolite concentrations of the folate pathway in individuals with Down syndrome. | 2013 Apr | 5 |
49 | 23552564 | Exploration of 2, 4-diaminopyrimidine and 2, 4-diamino-s-triazine derivatives as potential antifilarial agents. | 2013 Jul | 1 |
50 | 23707606 | Human endothelial dihydrofolate reductase low activity limits vascular tetrahydrobiopterin recycling. | 2013 Oct | 2 |