Lovastatin

3-hydroxy-3-methylglutaryl-Coenzyme A reductase ; Mus musculus







27 Article(s)
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1 33740503 Acetaldehyde Dehydrogenase 2 regulates HMG-CoA reductase stability and cholesterol synthesis in the liver. 2021 May 1
2 32184566 Annatto-Derived Tocotrienol Promotes Mineralization of MC3T3-E1 Cells by Enhancing BMP-2 Protein Expression via Inhibiting RhoA Activation and HMG-CoA Reductase Gene Expression. 2020 1
3 31599189 Cholesterol depletion sensitizes gallbladder cancer to cisplatin by impairing DNA damage response. 2019 Dec 4
4 27129778 Contribution of Accelerated Degradation to Feedback Regulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase and Cholesterol Metabolism in the Liver. 2016 Jun 24 2
5 27277576 Lovastatin, but not orlistat, reduces intestinal polyp volume in an ApcMin/+ mouse model. 2016 Aug 1
6 27884413 Peroxisome proliferator-activated receptor γ down-regulation mediates the inhibitory effect of d-δ-tocotrienol on the differentiation of murine 3T3-F442A preadipocytes. 2016 Dec 1
7 23352156 Fragile X syndrome therapeutics: translation, meet translational medicine. 2013 Jan 23 1
8 21751201 Synergistic inhibitory effect of apomine and lovastatin on osteosarcoma cell growth. 2012 Feb 1 1
9 20404351 Scavenger receptor-B1 and luteal function in mice. 2010 Aug 1
10 16203826 Erythropoietin receptor signal transduction requires protein geranylgeranylation. 2006 Jan 1
11 15605420 Induction of macrophage elastase (MMP-12) gene expression by statins. 2005 Jul 1
12 15699169 Suppression of autoimmune retinal disease by lovastatin does not require Th2 cytokine induction. 2005 Feb 15 1
13 16271875 The HMG-CoA reductase inhibitor lovastatin reverses the learning and attention deficits in a mouse model of neurofibromatosis type 1. 2005 Nov 8 2
14 11908910 Farnesol and geranylgeraniol: prevention and reversion of lovastatin-induced effects in NIH3T3 cells. 2002 Feb 1
15 9802623 Reduction of mouse mammary tumor formation and metastasis by lovastatin, an inhibitor of the mevalonate pathway of cholesterol synthesis. 1998 Jul 1
16 8773465 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor impairs cell p4fferentiation in cultured adipogenic cells (3T3-L1). 1996 Apr 22 1
17 7475995 Tissue-selective inhibition of sterol synthesis in mice by pravastatin sodium after a single or repeated oral administrations. 1995 Aug 1
18 7487365 Synergistic antiproliferative activity of tumor necrosis factor alpha (TNF-alpha) and lovastatin. 1994 1
19 8010162 Characterization of the response of growth and differentiation to lipoproteins and agents affecting cholesterol metabolism in murine neuroblastoma cells. 1994 Feb 2
20 7860224 Metastasis of B16F10 mouse melanoma inhibited by lovastatin, an inhibitor of cholesterol biosynthesis. 1993 2
21 8345219 Inhibition of cholesterol and sphingolipid synthesis causes paradoxical effects on permeability barrier homeostasis. 1993 Aug 1
22 1311272 Transcriptional derepression of the murine Cyp1a-1 gene by mevinolin. 1992 Jan 6 1
23 2243142 Cholesterol synthesis is required for cutaneous barrier function in mice. 1990 Nov 2
24 2722887 Post-translational isoprenylation of cellular proteins is altered in response to mevalonate availability. 1989 Jun 15 1
25 3040778 The effect of factors released from the tumor-transformed cells on DNA synthesis, mitosis, and cellular enlargement in 3T3 fibroblasts. 1987 Aug 2
26 3851809 Differentiation of neuroblastoma cells induced by an inhibitor of mevalonate synthesis: relation of neurite outgrowth and acetylcholinesterase activity to changes in cell proliferation and blocked isoprenoid synthesis. 1985 Dec 1
27 6903572 Feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in livers of mice treated with mevinolin, a competitive inhibitor of the reductase. 1980 Nov 6