| 1 |
33245660 | 11β-Hydroxylase (CYP11B1) gene variants and new-onset depression in later life. | 2021 Jan 4 |
1 |
| 2 |
34015331 | Structural and functional insights into aldosterone synthase interaction with its redox partner protein adrenodoxin. | 2021 Jan-Jun |
1 |
| 3 |
34247511 | Aldosterone Synthase Structure With Cushing Disease Drug LCI699 Highlights Avenues for Selective CYP11B Drug Design. | 2021 Sep |
1 |
| 4 |
34384396 | Concurrence of overt Cushing's syndrome and primary aldosteronism accompanied by aldosterone-producing cell cluster in adjacent adrenal cortex: case report. | 2021 Aug 12 |
1 |
| 5 |
34485929 | Spatially restricted substrate-binding site of cortisol-synthesizing CYP11B1 limits multiple hydroxylations and hinders aldosterone synthesis. | 2021 |
2 |
| 6 |
31613736 | Effects of Adipocyte-derived Factors on the Adrenal Cortex. | 2020 |
3 |
| 7 |
32203088 | Extra-adrenal glucocorticoid biosynthesis: implications for autoimmune and inflammatory disorders. | 2020 May |
1 |
| 8 |
32751564 | Incomplete Pattern of Steroidogenic Protein Expression in Functioning Adrenocortical Carcinomas. | 2020 Jul 30 |
1 |
| 9 |
30425102 | Structure of human cortisol-producing cytochrome P450 11B1 bound to the breast cancer drug fadrozole provides insights for drug design. | 2019 Jan 11 |
1 |
| 10 |
30572739 | Drug design strategies for Cushing's syndrome. | 2019 Feb |
2 |
| 11 |
30769265 | Benzophenones as xanthone-open model CYP11B1 inhibitors potentially useful for promoting wound healing. | 2019 May |
1 |
| 12 |
30965118 | Identification of the fungicide epoxiconazole by virtual screening and biological assessment as inhibitor of human 11β-hydroxylase and aldosterone synthase. | 2019 Sep |
1 |
| 13 |
31351131 | The crosstalk between aldosterone and calcium metabolism in primary aldosteronism: A possible calcium metabolism-associated aberrant "neoplastic" steroidogenesis in adrenals. | 2019 Oct |
2 |
| 14 |
31400391 | Genetic and epigenetic analyses of aldosterone-producing adenoma with hypercortisolemia. | 2019 Nov |
1 |
| 15 |
31484828 | In situ metabolomics of aldosterone-producing adenomas. | 2019 Sep 5 |
2 |
| 16 |
31666955 | Synchronous aldosterone- and cortisol-producing adrenocortical adenomas diagnosed using CYP11B immunohistochemistry. | 2019 |
1 |
| 17 |
28747362 | Alterations of adrenal steroidomic profiles in preterm infants at birth. | 2018 Mar |
1 |
| 18 |
29878770 | Discovery of Novel Pyrazole-Based Selective Aldosterone Synthase (CYP11B2) Inhibitors: A New Template to Coordinate the Heme-Iron Motif of CYP11B2. | 2018 Jul 12 |
1 |
| 19 |
28514642 | Congenital adrenal hyperplasia due to 11-hydroxylase deficiency-Compound heterozygous mutations of a prevalent and two novel CYP11B1 mutations. | 2017 Aug 30 |
1 |
| 20 |
28894201 | Cortisol overproduction results from DNA methylation of CYP11B1 in hypercortisolemia. | 2017 Sep 11 |
3 |
| 21 |
29312923 | Pharmacophore Modeling and in Silico/in Vitro Screening for Human Cytochrome P450 11B1 and Cytochrome P450 11B2 Inhibitors. | 2017 |
2 |
| 22 |
26514241 | Novel functionalized 5-(phenoxymethyl)-1,3-dioxane analogs exhibiting cytochrome P450 inhibition: a patent evaluation WO2015048311 (A1). | 2016 |
2 |
| 23 |
26597777 | Intratumoral heterogeneity of steroidogenesis in aldosterone-producing adenoma revealed by intensive double- and triple-immunostaining for CYP11B2/B1 and CYP17. | 2016 Feb 15 |
2 |
| 24 |
26795197 | Inhibitors of 11β-Hydroxylase (CYP11B1) for Treating Diseases Related to Excess Cortisol. | 2016 |
2 |
| 25 |
26854589 | The potential of targeting CYP11B. | 2016 Aug |
1 |
| 26 |
27119751 | Immunohistochemistry of the adrenal in primary aldosteronism. | 2016 Jun |
1 |
| 27 |
25462231 | Discovery of new 7-substituted-4-imidazolylmethyl coumarins and 4'-substituted-2-imidazolyl acetophenones open analogues as potent and selective inhibitors of steroid-11β-hydroxylase. | 2015 Jan 7 |
1 |
| 28 |
25584832 | Combined pharmacophore modeling, 3D-QSAR, homology modeling and docking studies on CYP11B1 inhibitors. | 2015 Jan 9 |
2 |
| 29 |
25880059 | A recombinant CYP11B1 dependent Escherichia coli biocatalyst for selective cortisol production and optimization towards a preparative scale. | 2015 Feb 25 |
3 |
| 30 |
26303746 | Development of CYP11B1 and CYP11B2 assays utilizing homogenates of adrenal glands: Utility of monkey as a surrogate for human. | 2015 Nov |
1 |
| 31 |
24325867 | Development of monoclonal antibodies against human CYP11B1 and CYP11B2. | 2014 Mar 5 |
1 |
| 32 |
24810847 | Expression of 11β-hydroxysteroid dehydrogenase 1 and 2 in patients with chronic rhinosinusitis and their possible contribution to local glucocorticoid activation in sinus mucosa. | 2014 Oct |
1 |
| 33 |
23443813 | Histopathological diagnosis of primary aldosteronism using CYP11B2 immunohistochemistry. | 2013 Apr |
2 |
| 34 |
23836801 | MicroRNA-24 is a novel regulator of aldosterone and cortisol production in the human adrenal cortex. | 2013 Sep |
1 |
| 35 |
23940125 | A diagnosis not to be missed: nonclassic steroid 11β-hydroxylase deficiency presenting with premature adrenarche and hirsutism. | 2013 Oct |
1 |
| 36 |
24900631 | Discovery and in Vivo Evaluation of Potent Dual CYP11B2 (Aldosterone Synthase) and CYP11B1 Inhibitors. | 2013 Dec 12 |
1 |
| 37 |
22079243 | Regulation of human CYP11B1 and CYP11B2 promoters by transposable elements and conserved cis elements. | 2012 Jan |
1 |
| 38 |
22172629 | Flavonoids exhibit diverse effects on CYP11B1 expression and cortisol synthesis. | 2012 Feb 1 |
2 |
| 39 |
21094146 | Steroid synthesis by primary human keratinocytes; implications for skin disease. | 2011 Jan 7 |
1 |
| 40 |
21164264 | Role of genetic variation in regulation of aldosterone biosynthesis. | 2011 |
1 |
| 41 |
21239489 | Cortisol synthesis in epidermis is induced by IL-1 and tissue injury. | 2011 Mar 25 |
1 |
| 42 |
21848792 | Increased expression of CYP17 and CYP11B1 in subclinical Cushing's syndrome due to adrenal adenomas. | 2011 Oct |
1 |
| 43 |
24900247 | First Selective CYP11B1 Inhibitors for the Treatment of Cortisol-Dependent Diseases. | 2011 Jan 13 |
1 |
| 44 |
24900349 | Optimization of the First Selective Steroid-11β-hydroxylase (CYP11B1) Inhibitors for the Treatment of Cortisol Dependent Diseases. | 2011 Aug 11 |
4 |
| 45 |
20615692 | The discovery of potent inhibitors of aldosterone synthase that exhibit selectivity over 11-beta-hydroxylase. | 2010 Aug 1 |
1 |
| 46 |
19164467 | Torcetrapib induces aldosterone and cortisol production by an intracellular calcium-mediated mechanism independently of cholesteryl ester transfer protein inhibition. | 2009 May |
1 |
| 47 |
19342457 | Regulation of aldosterone and cortisol production by the transcriptional repressor neuron restrictive silencer factor. | 2009 Jul |
2 |
| 48 |
19564722 | Increased ratio of mRNA expression of the genes CYP17 and CYP11B1 indicates autonomous cortisol production in adrenocortical tumors. | 2009 Nov |
1 |
| 49 |
19622340 | Coexpression of CYP11B2 or CYP11B1 with adrenodoxin and adrenodoxin reductase for assessing the potency and selectivity of aldosterone synthase inhibitors. | 2009 Nov 1 |
1 |
| 50 |
17980006 | Effect of variation in CYP11B1 and CYP11B2 on corticosteroid phenotype and hypothalamic-pituitary-adrenal axis activity in hypertensive and normotensive subjects. | 2008 May |
1 |