| 1 |
34806938 | Evaluation of MTBH, a novel hesperetin derivative, on the activity of hepatic cytochrome P450 isoform in vitro and in vivo using a cocktail method by HPLC-MS/MS. | 2021 Dec |
1 |
| 2 |
24090815 | Mode of action of ethyl tertiary-butyl ether hepatotumorigenicity in the rat: evidence for a role of oxidative stress via activation of CAR, PXR and PPAR signaling pathways. | 2013 Dec 1 |
1 |
| 3 |
22245121 | Hepatocellular hypertrophy and cell proliferation in Sprague-Dawley rats from dietary exposure to potassium perfluorooctanesulfonate results from increased expression of xenosensor nuclear receptors PPARα and CAR/PXR. | 2012 Mar 11 |
1 |
| 4 |
20551240 | Liverbeads: a practical and relevant in vitro model for gene induction investigations. | 2010 Sep |
1 |
| 5 |
18486294 | Inhibitory effects of a dietary phytochemical 3,3'-diindolylmethane on the phenobarbital-induced hepatic CYP mRNA expression and CYP-catalyzed reactions in female rats. | 2008 Jul |
1 |
| 6 |
18796496 | Global liver proteomics of rats exposed for 5 days to phenobarbital identifies changes associated with cancer and with CYP metabolism. | 2008 Dec |
2 |
| 7 |
16815962 | Dietary inulin alleviates hepatic steatosis and xenobiotics-induced liver injury in rats fed a high-fat and high-sucrose diet: association with the suppression of hepatic cytochrome P450 and hepatocyte nuclear factor 4alpha expression. | 2006 Oct |
2 |
| 8 |
17069428 | An evaluation of para toluene-sulfonamide metabolism and effect with regard to CYP isoforms, P-glycoprotein, and drug interactions. | 2006 Oct |
1 |
| 9 |
15596064 | Microarray analysis on CYPs expression in pregnant rats after treatment with pregnenolone-16alpha-carbonitrile and phenobarbital. | 2005 Feb |
2 |
| 10 |
15713442 | Induction of cytochrome P450 isozymes by phenobarbital in pregnant rat and fetal livers and placenta. | 2005 Apr |
2 |
| 11 |
16421897 | Quantification of the expression and inducibility of 12 rat cytochrome P450 isoforms by quantitative RT-PCR. | 2005 |
1 |
| 12 |
15607757 | An in vivo and in vitro comparison of CYP induction in rat liver and intestine using slices and quantitative RT-PCR. | 2004 Dec 30 |
1 |
| 13 |
12837975 | Phenobarbital-imprinted overinduction of adult constituent CYP isoforms. | 2003 Aug |
1 |
| 14 |
12933323 | The herbicide metolachlor induces liver cytochrome P450s 2B1/2 and 3A1/2, but not thyroxine-uridine dinucleotide phosphate glucuronosyltransferase and associated thyroid gland activity. | 2003 Jul-Aug |
1 |
| 15 |
14561525 | Metabolism of medroxyprogesterone acetate (MPA) via CYP enzymes in vitro and effect of MPA on bleeding time in female rats in dependence on CYP activity in vivo. | 2003 Nov 7 |
1 |
| 16 |
11841808 | Differential regulation of multidrug resistance-associated protein 2 (MRP2) and cytochromes P450 2B1/2 and 3A1/2 in phenobarbital-treated hepatocytes. | 2002 Jan 15 |
2 |
| 17 |
12296987 | Permissive and suppressive effects of dexamethasone on enzyme induction in hepatocyte co-cultures. | 2002 Aug |
1 |
| 18 |
11159809 | Stereochemical aspects of vinylcyclohexene bioactivation in rodent hepatic microsomes and purified human cytochrome P450 enzyme systems. | 2001 Feb |
1 |
| 19 |
11262762 | Collagen type I gel cultures of adult rat hepatocytes as a screening induction model for cytochrome P450-dependent enzymes. | 2001 Mar-Apr |
1 |
| 20 |
11377398 | Induction of cytochrome P450 2B1 by pyrethroids in primary rat hepatocyte cultures. | 2001 Jul 1 |
1 |
| 21 |
11714877 | Midazolam is a phenobarbital-like cytochrome p450 inducer in rats. | 2001 Dec |
1 |
| 22 |
10670824 | Induction of rat hepatic drug metabolizing enzymes by dimethylcyclosiloxanes. | 2000 Jan 15 |
1 |
| 23 |
10772642 | Detection of chemical-induced differential expression of rat hepatic cytochrome P450 mRNA transcripts using branched DNA signal amplification technology. | 2000 May |
1 |
| 24 |
10945841 | Activation of cytochrome P450 gene expression in the rat brain by phenobarbital-like inducers. | 2000 Sep |
2 |
| 25 |
9890442 | Insulin-mediated modulation of cytochrome P450 gene induction profiles in primary rat hepatocyte cultures. | 1999 |
1 |
| 26 |
10036216 | Phenobarbital induction of CYP2B1/2 in primary hepatocytes: endocrine regulation and evidence for a single pathway for multiple inducers. | 1999 Feb 15 |
2 |
| 27 |
9630454 | Endocrine factors modulate the phenobarbital-mediated induction of cytochromes P450 and phase II enzymes in a similar strain-dependent manner. | 1998 May |
3 |
| 28 |
9630843 | Involvement of CYP3A1, 2B1, and 2E1 in C-8 hydroxylation and CYP 1A2 and flavin-containing monooxygenase in N-demethylation of caffeine; identified by using inducer treated rat liver microsomes that are characterized with testosterone metabolic patterns. | 1998 May 1 |
2 |
| 29 |
9664231 | Differential induction of cytochrome P450 gene expression by 4n-alkyl-methylenedioxybenzenes in primary rat hepatocyte cultures. | 1998 |
1 |
| 30 |
9972461 | Dose-response relationships for cytochrome P450 induction by phenobarbital in the cotton rat (Sigmodon hispidus). | 1998 Nov |
1 |
| 31 |
9185622 | Characterization of a pretranscriptional pathway for induction by phenobarbital of cytochrome P450 3A23 in primary cultures of adult rat hepatocytes. | 1997 Jun 1 |
5 |
| 32 |
9262383 | An okadaic acid-sensitive pathway involved in the phenobarbital-mediated induction of CYP2B gene expression in primary rat hepatocyte cultures. | 1997 Aug |
2 |
| 33 |
8558437 | Forskolin-mediated induction of CYP3A1 mRNA expression in primary rat hepatocytes is independent of elevated intracellular cyclic AMP. | 1996 Jan |
1 |
| 34 |
7587963 | Induction of liver microsomal cytochrome P450 in cynomolgus monkeys. | 1995 Jul |
1 |
| 35 |
7646073 | Phenobarbital induction of CYP2B1, CYP2B2, and CYP3A1 in rat liver: genetic differences in a common regulatory mechanism. | 1995 Aug 20 |
3 |
| 36 |
7748182 | Species differences in the covalent binding of [14C]tamoxifen to liver microsomes and the forms of cytochrome P450 involved. | 1995 Apr 18 |
1 |
| 37 |
7759530 | cAMP-associated inhibition of phenobarbital-inducible cytochrome P450 gene expression in primary rat hepatocyte cultures. | 1995 May 26 |
2 |
| 38 |
7773300 | Modulation of xenobiotic-inducible cytochrome P450 gene expression by dexamethasone in primary rat hepatocytes. | 1995 Feb |
2 |
| 39 |
7528203 | A major glucocorticoid-inducible P450 in rat liver is not P450 3A1. | 1994 Jul |
10 |
| 40 |
7979401 | The induction of five rat hepatic P450 cytochromes by phenobarbital and similarly acting compounds is regulated by a sexually dimorphic, dietary-dependent endocrine factor that is highly strain specific. | 1994 Nov 15 |
2 |
| 41 |
8001226 | Involvement of cytochrome P4503A in catalysis of tamoxifen activation and covalent binding to rat and human liver microsomes. | 1994 Dec |
1 |
| 42 |
8104124 | Metabolism of the antimammary cancer antiestrogenic agent tamoxifen. I. Cytochrome P-450-catalyzed N-demethylation and 4-hydroxylation. | 1993 Jul-Aug |
1 |
| 43 |
8249615 | Combined action of phenobarbital and dexamethasone on the activity of rat liver P450 system. | 1993 Sep |
3 |
| 44 |
1417000 | Effect of dexamethasone and phenobarbital on run-on transcription rate and CYP3A mRNA concentration in rat liver: changes during development. | 1992 Nov 1 |
1 |
| 45 |
1585371 | Acute stimulation of trifluoroethene defluorination and cytochrome P450 inactivation in the rat by exposure to isoflurane. | 1992 May |
1 |
| 46 |
1731631 | Cloning and characterization of a novel CYP3A1 allelic variant: analysis of CYP3A1 and CYP3A2 sex-hormone-dependent expression reveals that the CYP3A2 gene is regulated by testosterone. | 1992 Feb 14 |
1 |
| 47 |
1740154 | Zonation of cytochrome P450 isozyme expression and induction in rat liver. | 1992 Feb 15 |
2 |
| 48 |
1859452 | Comparison of cytochrome P450 isoenzyme profiles in rat liver and hepatocyte cultures. The effects of model inducers on apoproteins and biotransformation activities. | 1991 Jul 5 |
1 |
| 49 |
1989519 | Ethanol increases cytochromes P450IIE, IIB1/2, and IIIA in cultured rat hepatocytes. | 1991 Feb 1 |
1 |
| 50 |
2039754 | Microsomal cytochrome P450-dependent steroid metabolism in male sheep liver. Quantitative importance of 6 beta-hydroxylation and evidence for the involvement of a P450 from the IIIA subfamily in the pathway. | 1991 May |
1 |