Methylnitrosourea

O-6-methylguanine-DNA methyltransferase ; Homo sapiens







20 Article(s)
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1 26667451 DNA Alkylating Agent Protects Against Spontaneous Hepatocellular Carcinoma Regardless of O6-Methylguanine-DNA Methyltransferase Status. 2016 Mar 2
2 23288051 Influence of DNA repair on nonlinear dose-responses for mutation. 2013 Mar 1
3 23620436 A new proposed rodent model of chemically induced prostate carcinogenesis: distinct time-course prostate cancer progression in the dorsolateral and ventral lobes. 2013 Aug 1
4 22487424 Pol kappa partially rescues MMR-dependent cytotoxicity of O6-methylguanine. 2012 Jun 1 1
5 22199294 Investigation of cell death induced by N-methyl-N-nitrosourea in cell lines of human origin and implication of RNA binding protein alterations. 2011 Dec 3
6 17507295 Methylation damage response in hematopoietic progenitor cells. 2007 Aug 1 3
7 15870882 Deficient MGMT and proficient hMLH1 expression renders gallbladder carcinoma cells sensitive to alkylating agents through G2-M cell cycle arrest. 2005 Jun 7
8 14712205 Generating mutations but providing chemosensitivity: the role of O6-methylguanine DNA methyltransferase in human cancer. 2004 Jan 8 1
9 13679151 Roles of MGMT and MLH1 proteins in alkylation-induced apoptosis and mutagenesis. 2003 Oct 7 1
10 10866320 Epigenetic regulation of the MGMT and hMSH6 DNA repair genes in cells resistant to methylating agents. 2000 Jun 15 2
11 10439048 Mice defective in the DNA mismatch gene PMS2 are hypersensitive to MNU induced thymic lymphoma and are partially protected by transgenic expression of human MGMT. 1999 Jul 29 2
12 10469609 Transgenic expression of human MGMT blocks the hypersensitivity of PMS2-deficient mice to low dose MNU thymic lymphomagenesis. 1999 Sep 2
13 9488483 Implication of localization of human DNA repair enzyme O6-methylguanine-DNA methyltransferase at active transcription sites in transcription-repair coupling of the mutagenic O6-methylguanine lesion. 1998 Mar 2
14 9366529 Potentiation of lymphomagenesis by methylnitrosourea in mice transgenic for LMO1 is blocked by O6-alkylguanine DNA-alkyltransferase. 1997 Oct 23 3
15 8645346 Retrovirus-mediated transfer of the human O6-methylguanine-DNA methyltransferase gene into a murine hematopoietic stem cell line and resistance to the toxic effects of certain alkylating agents. 1996 May 3 1
16 7767963 The immature thymocyte is protected from N-methylnitrosourea-induced lymphoma by the human MGMT-CD2 transgene. 1995 May 3
17 8062258 Rapid repair of O6-methylguanine-DNA adducts protects transgenic mice from N-methylnitrosourea-induced thymic lymphomas. 1994 Sep 1 1
18 1638685 Cytotoxic and mutagenic effects of methylnitrosourea in two human fetal fibroblast strains differing in O6-methylguanine-DNA methyltransferase activity. 1992 Jul 1
19 1657427 Transfection and expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents. 1991 Oct 2
20 1875945 Inducibility of the DNA repair gene encoding O6-methylguanine-DNA methyltransferase in mammalian cells by DNA-damaging treatments. 1991 Sep 1