Eflornithine

ornithine decarboxylase 1 ; Rattus norvegicus







317 Article(s)
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1 33318864 Hippocampal ornithine decarboxylase/spermidine pathway mediates H2S-alleviated cognitive impairment in diabetic rats: Involving enhancment of hippocampal autophagic flux. 2021 Jan 2
2 27074051 Endoplasmic Reticulum Stress is Involved in DFMO Attenuating Isoproterenol-Induced Cardiac Hypertrophy in Rats. 2016 3
3 24464033 Akt and Erk1/2 activate the ornithine decarboxylase/polyamine system in cardioprotective ischemic preconditioning in rats: the role of mitochondrial permeability transition pores. 2014 May 2
4 24666424 Inhibition of polyamine formation antagonizes vascular smooth muscle cell proliferation and preserves the contractile phenotype. 2014 Nov 2
5 25323967 Polyamine depletion attenuates isoproterenol-induced hypertrophy and endoplasmic reticulum stress in cardiomyocytes. 2014 1
6 25404991 Exercise training preserves ischemic preconditioning in aged rat hearts by restoring the myocardial polyamine pool. 2014 1
7 23680596 Local inhibition of ornithine decarboxylase reduces vascular stenosis in a murine model of carotid injury. 2013 Oct 9 2
8 21512157 Polyamines mediate glutamine-dependent induction of the intestinal epithelial heat shock response. 2011 Jul 4
9 20013009 Overexpression of ornithine decarboxylase increases myogenic potential of H9c2 rat myoblasts. 2010 Feb 1
10 18368465 Polyamine synthesis inhibition induces S phase cell cycle arrest in vascular smooth muscle cells. 2009 Feb 1
11 19136059 Role of polyamines in p53-dependent apoptosis of intestinal epithelial cells. 2009 Apr 2
12 20524478 Effect of difluoromethylornithine on thyroid function in rats. 2009 Apr-Jun 2
13 18670363 Role of putrescine on androgen-elicited positive inotropism in the left atrium of rats. 2008 Aug 1
14 18755180 Putrescine modulation of acute activation of the beta-adrenergic system in the left atrium of rat. 2008 Nov 19 1
15 17549408 Follow-up of tumor development in the colons of living rats and implications for chemoprevention trials: assessment of aspirin-difluoromethylornithine combination. 2007 Jul 1
16 16669788 Integrin beta3-mediated Src activation regulates apoptosis in IEC-6 cells via Akt and STAT3. 2006 Aug 1 3
17 16944279 Modulation of cell proliferation and polyamine metabolism in rat liver cell cultures by the iron chelator O-trensox. 2006 Dec 2
18 16320593 [Effect of alpha-difluoromethylornithine on the expression of ODC mRNA in the cortex and hippocampus in rats after cerebral ischemia reperfusion]. 2005 Oct 6
19 12816757 RhoA stimulates IEC-6 cell proliferation by increasing polyamine-dependent Cdk2 activity. 2003 Oct 1
20 12885432 Long-lasting CNS effects of a short-term chemical knockout of ornithine decarboxylase during development: nicotinic cholinergic receptor upregulation and subtle macromolecular changes in adulthood. 2003 Aug 15 3
21 12909191 The opposing effects of endothelin-1 and C-type natriuretic peptide on apoptosis of neonatal rat cardiac myocytes. 2003 Aug 1 2
22 14600289 Hexachlorobenzene-induced early changes in ornithine decarboxylase and protein tyrosine kinase activities, polyamines and c-Myc, c-Fos and c-Jun proto-oncogenes in rat liver. 2003 Dec 1
23 14649727 Ornithine decarboxylase activity in in vivo and in vitro models of cerebral ischemia. 2003 Dec 3
24 11883715 Inhibition of placental ornithine decarboxylase by DL-alpha-difluoro-methyl ornithine causes fetal growth restriction in rat. 2002 Feb 8 6
25 11911991 Quantitation of polyamines in hypothalamus and pituitary of female and male developing rats. 2002 Apr 19 1
26 11997243 Polyamine depletion prevents camptothecin-induced apoptosis by inhibiting the release of cytochrome c. 2002 Jun 2
27 12105848 RhoA inactivation inhibits cell migration but does not mediate the effects of polyamine depletion. 2002 Jul 1
28 12452334 Decreased ornithine decarboxylase activity in the kidneys of Dahl salt-sensitive rats. 2002 Sep 2
29 12467913 Mechanism of the antiulcerogenic effect of Ganoderma lucidum polysaccharides on indomethacin-induced lesions in the rat. 2002 Dec 27 2
30 12597149 Chemoprevention of prostate carcinogenesis by DFMO and/or finasteride treatment in male Wistar rats. 2002 Nov-Dec 1
31 11160138 Ornithine decarboxylase, kidney size, and the tubular hypothesis of glomerular hyperfiltration in experimental diabetes. 2001 Jan 3
32 11303587 Alpha-difluoromethylornithine induction of apoptosis: a mechanism which reverses pre-established cell proliferation and cancer initiation in esophageal carcinogenesis in zinc-deficient rats. 2001 Mar 2
33 11331080 A mechanistic study of proliferation induced by Angelica sinensis in a normal gastric epithelial cell line. 2001 Jun 1 1
34 11408253 Polyamine depletion arrests growth of IEC-6 and Caco-2 cells by different mechanisms. 2001 Jul 2
35 11430920 Increases in ornithine decarboxylase activity in the positive inotropism induced by androgens in isolated left atrium of the rat. 2001 Jun 22 1
36 11435720 Induction of gastric ornithine decarboxylase in early weaning rats. 2001 3
37 11590175 Polyamine depletion induces rapid NF-kappa B activation in IEC-6 cells. 2001 Dec 7 3
38 11592976 Role of p42/p44 mitogen-activated-protein kinase and p21waf1/cip1 in the regulation of vascular smooth muscle cell proliferation by nitric oxide. 2001 Oct 23 6
39 10607762 Acute glomerular upregulation of ornithine decarboxylase is not essential for mesangial cell proliferation and matrix expansion in anti-Thy-1-nephritis. 2000 Jan 2
40 10712236 Polyamine depletion delays apoptosis of rat intestinal epithelial cells. 2000 Mar 4
41 10840185 Minimal behavioral effects from developmental cerebellar stunting in young rats induced by postnatal treatment with alpha-difluoromethylornithine. 2000 May-Jun 2
42 10913016 Hypertrophic effect of selective beta(1)-adrenoceptor stimulation on ventricular cardiomyocytes from adult rat. 2000 Aug 3
43 11003584 Expression of the TGF-beta receptor gene and sensitivity to growth inhibition following polyamine depletion. 2000 Oct 2
44 11064274 Attenuation of isoproterenol-mediated myocardial injury in rat by an inhibitor of polyamine synthesis. 2000 Sep-Oct 3
45 11134585 Neonatal polyamine depletion by alpha-difluoromethylornithine: effects on adenylyl cyclase cell signaling are separable from effects on brain region growth. 2000 Dec 22 2
46 9890191 Thiols and polyamines in the cytoprotective effect of taurine on carbon tetrachloride-induced hepatotoxicity. 1999 1
47 10069996 Polyamine depletion arrests cell cycle and induces inhibitors p21(Waf1/Cip1), p27(Kip1), and p53 in IEC-6 cells. 1999 Mar 2
48 10445761 Developmental toxicity studies of 2-(difluoromethyl)-dl-ornithine (DFMO) in rats and rabbits. 1999 Jul 2
49 10510592 Role of tyrosine kinase, ODC, and p34cdc2 kinase and cyclin B-associated cdc2 in jejunal enterocyte proliferation, maturation, and exfoliation in diabetic and DFMO-treated rats. 1999 Sep 2
50 10550568 Difluoromethylornithine in combination with tamoxifen in female rats: 13-week oral toxicity study. 1999 2