argatroban

coagulation factor II ; Rattus norvegicus







41 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 29971544 Attenuation of type-1 diabetes-induced cardiovascular dysfunctions by direct thrombin inhibitor in rats: a mechanistic study. 2019 Jan 1
2 31157200 Supramolecular Aptamers on Graphene Oxide for Efficient Inhibition of Thrombin Activity. 2019 1
3 31175488 Lipopolysaccharide-Induced Hemolysis Is Abolished by Inhibition of Thrombin Generation but Not Inhibition of Platelet Aggregation. 2019 Oct 2
4 31666085 Role of non-macrophage cell-derived HMGB1 in oxaliplatin-induced peripheral neuropathy and its prevention by the thrombin/thrombomodulin system in rodents: negative impact of anticoagulants. 2019 Oct 30 1
5 28695302 Argatroban Attenuates Diabetic Cardiomyopathy in Rats by Reducing Fibrosis, Inflammation, Apoptosis, and Protease-Activated Receptor Expression. 2017 Jun 2
6 26342829 Concentration-Dependent Dual Role of Thrombin in Protection of Cultured Rat Cortical Neurons. 2015 Nov 1
7 24473182 Direct thrombin inhibitor argatroban reduces stroke damage in 2 different models. 2014 Mar 2
8 22649241 Thrombin activity associated with neuronal damage during acute focal ischemia. 2012 May 30 1
9 21803126 Systemic administration of argatroban inhibits protease-activated receptor-1 expression in perihematomal tissue in rats with intracerebral hemorrhage. 2011 Oct 10 4
10 20705928 Thrombin mediates severe neurovascular injury during ischemia. 2010 Oct 1
11 20806115 Argatroban administration reduces leukocyte adhesion and improves capillary perfusion within the intestinal microcirculation in experimental sepsis. 2010 Nov 2
12 19228846 Thrombin inhibition by argatroban ameliorates early brain injury and improves neurological outcomes after experimental subarachnoid hemorrhage in rats. 2009 Apr 3
13 18622025 Thrombin enhances the production of monocyte chemoattractant protein-1 and macrophage inflammatory protein-2 in cultured rat glomerular epithelial cells. 2008 Nov 2
14 19388346 Thrombin enhances glioma growth. 2008 2
15 17498698 Involvement of thrombin and mitogen-activated protein kinase pathways in hemorrhagic brain injury. 2007 Jul 1
16 15665510 Systemic administration of argatroban reduces secondary brain damage in a rat model of intracerebral hemorrhage: histopathological assessment. 2005 1
17 15975137 The role of thrombin in gliomas. 2005 Sep 1
18 15980248 Thrombin inhibitor reduces leukocyte-endothelial cell interactions and vascular leakage after scatter laser photocoagulation. 2005 Jul 1
19 16463890 Systemic use of argatroban reduces tumor mass, attenuates neurological deficits and prolongs survival time in rat glioma models. 2005 2
20 12869718 Argatroban attenuates leukocyte- and platelet-endothelial cell interactions after transient retinal ischemia. 2003 Aug 1
21 14753434 Mild hypothermia enhances the neuroprotective effects of a selective thrombin inhibitor following transient focal ischemia in rats. 2003 2
22 14753486 Effect of delayed argatroban treatment on intracerebral hemorrhage-induced edema in the rat. 2003 1
23 14753495 A thrombin inhibitor reduces brain edema, glioma mass and neurological deficits in a rat glioma model. 2003 1
24 12468805 Delayed argatroban treatment reduces edema in a rat model of intracerebral hemorrhage. 2002 Dec 1
25 10706937 Heparin cofactor II inhibits thrombus formation in a rat thrombosis model. 2000 Apr 1 1
26 10959702 Activity of a sub-cutaneously administered novel mixed micellar formulation of argatroban in rat and rabbit models of venous thrombosis. 2000 Aug 1
27 9870892 Synergistic antithrombotic effects of argatroban and ticlopidine in the rat venous thrombosis model. 1998 Dec 15 1
28 9175233 Adjuvant effect of argatroban on staphylokinase induced thrombolysis of platelet rich thrombi in rat mesenteric venules in vivo. 1997 Apr 15 1
29 9469624 Effect of argatroban, a selective thrombin inhibitor, on animal models of cerebral thrombosis. 1997 1
30 8768731 Effects of a thrombin inhibitor, argatroban, on ischemic brain damage in the rat distal middle cerebral artery occlusion model. 1996 Aug 1
31 8797131 Low-molecular-weight heparin (fragmin) and thrombin active-site inhibitor (argatroban) compared in experimental arterial and venous thrombosis and bleeding time. 1996 Jul 1
32 8944418 New model for in vivo studies of pharmacological interventions with endogenous fibrinolysis: effects of thrombin inhibitors. 1996 1
33 7559923 [Effect of argatroban on flap survival length]. 1995 Aug 1
34 7630043 Inhibitory effect of clopidogrel, vapiprost and argatroban on the middle cerebral artery thrombosis in the rat. 1995 Mar 1
35 8569051 Effect of argatroban on microthrombi formation and brain damage in the rat middle cerebral artery thrombosis model. 1995 Oct 1
36 7843647 Preventive effect of argatroban on ellagic acid-induced cerebral thromboembolism in rats. 1994 Nov-Dec 1
37 7889274 Antithrombotic actions of argatroban in rat models of venous, 'mixed' and arterial thrombosis, and its effects on the tail transection bleeding time. 1994 Dec 3
38 8225173 [Effects of platelet aggregating inhibitor on pulmonary metastases of tumor cells after surgical resection]. 1993 Sep 1
39 8331553 Effects of thrombin and thrombin receptor activating peptides on rat aortic vascular smooth muscle. 1993 Jul 2
40 8387299 Effects of thrombin receptor activating peptide on phosphoinositide hydrolysis and protein kinase C activation in cultured rat aortic smooth muscle cells: evidence for "tethered-ligand" activation of smooth muscle cell thrombin receptors. 1993 Apr 22 2
41 1957278 Effect of ticlopidine and other antithrombotics on the venous thrombosis induced by endothelial damage of jugular vein in rats. 1991 Aug 1 1