Mephenytoin

cytochrome P450 family 2 subfamily B member 6 ; Homo sapiens







18 Article(s)
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1 35194103 CYP2B6 allelic variants and non-genetic factors influence CYP2B6 enzyme function. 2022 Feb 22 1
2 31610395 Characterization of CYP2B6 K262R allelic variants by quantitative allele-specific proteomics using a QconCAT standard. 2020 Jan 30 1
3 25500267 Mechanism-based inactivation of cytochrome P450 2B6 by isoimperatorin. 2015 Jan 25 1
4 26126958 Metabolism of (-)-cis- and (-)-trans-rose oxide by cytochrome P450 enzymes in human liver microsomes. 2015 Dec 1
5 23648676 Cytochrome P450 metabolic activities in the small intestine of cynomolgus macaques bred in Cambodia, China, and Indonesia. 2013 1
6 18071681 Assessment of urinary mephenytoin metrics to phenotype for CYP2C19 and CYP2B6 activity. 2008 Apr 1
7 18350255 A model based assessment of the CYP2B6 and CYP2C19 inductive properties by artemisinin antimalarials: implications for combination regimens. 2008 Apr 1
8 12844133 Artemisinin autoinduction is caused by involvement of cytochrome P450 2B6 but not 2C9. 2003 Jul 2
9 11950782 Triethylenethiophosphoramide is a specific inhibitor of cytochrome P450 2B6: implications for cyclophosphamide metabolism. 2002 May 1
10 15618670 Metabolism of selegiline hydrochloride, a selective monoamine b-type inhibitor, in human liver microsomes. 2002 1
11 10997936 CYP2B6 mediates the in vitro hydroxylation of bupropion: potential drug interactions with other antidepressants. 2000 Oct 1
12 10101147 Monospecific antipeptide antibody to cytochrome P-450 2B6. 1999 Apr 1
13 9732386 Further characterization of the expression in liver and catalytic activity of CYP2B6. 1998 Sep 2
14 9241656 Examination of purported probes of human CYP2B6. 1997 Jun 1
15 8647857 Identification of residues 99, 220, and 221 of human cytochrome P450 2C19 as key determinants of omeprazole activity. 1996 May 24 2
16 8886603 Catalytic role of cytochrome P4502B6 in the N-demethylation of S-mephenytoin. 1996 Sep 1
17 1997003 Hydroxylation and formation of electrophilic metabolites of tienilic acid and its isomer by human liver microsomes. Catalysis by a cytochrome P450 IIC different from that responsible for mephenytoin hydroxylation. 1991 Feb 15 3
18 2134689 Pharmacogenetics and polymorphism of human P-450 which activates and detoxicates xenobiotics and carcinogens. 1990 2