Ketamine

cytochrome P450 family 2 subfamily B member 6 ; Homo sapiens







26 Article(s)
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1 33599403 Allelic and genotype frequencies of major CYP2B6 polymorphisms in the Pakistani population. 2021 Mar 1
2 31772310 Ketamine in seizure management and future pharmacogenomic considerations. 2020 Jun 1
3 30589555 Halogen Substitution Influences Ketamine Metabolism by Cytochrome P450 2B6: In Vitro and Computational Approaches. 2019 Feb 4 3
4 30906561 Nicotine oxidation by genetic variants of CYP2B6 and in human brain microsomes. 2019 Apr 1
5 28737446 Quantitative in vitro phenotyping and prediction of drug interaction potential of CYP2B6 substrates as victims. 2018 Jul 2
6 29621538 Ketamine and ketamine metabolites as novel estrogen receptor ligands: Induction of cytochrome P450 and AMPA glutamate receptor gene expression. 2018 Jun 1
7 30085944 Stereoselective Ketamine Metabolism by Genetic Variants of Cytochrome P450 CYP2B6 and Cytochrome P450 Oxidoreductase. 2018 Oct 9
8 28252572 Pharmacogenetics of Ketamine-Induced Emergence Phenomena: A Pilot Study. 2017 Mar/Apr 1
9 28858450 Ketamine for Depression, 5: Potential Pharmacokinetic and Pharmacodynamic Drug Interactions. 2017 Jul 2
10 27362518 Pharmacogenetics of Anesthesia: An Integrative Review. 2016 Jul-Aug 2
11 27709010 Insights into CYP2B6-mediated drug-drug interactions. 2016 Sep 1
12 27763886 CYP2B6*6 or Not CYP2B6*6-That Remains a Question for Precision Medicine and Ketamine! 2016 Dec 2
13 27763887 Role of Cytochrome P4502B6 Polymorphisms in Ketamine Metabolism and Clearance. 2016 Dec 6
14 25702819 CYP2B6*6 allele and age substantially reduce steady-state ketamine clearance in chronic pain patients: impact on adverse effects. 2015 Aug 12
15 23467454 Pharmacogenetics of cytochrome P450 2B6 (CYP2B6): advances on polymorphisms, mechanisms, and clinical relevance. 2013 1
16 23550066 The CYP2B6*6 allele significantly alters the N-demethylation of ketamine enantiomers in vitro. 2013 Jun 8
17 21508826 Effect of rifampicin on S-ketamine and S-norketamine plasma concentrations in healthy volunteers after intravenous S-ketamine administration. 2011 Jun 1
18 21716267 Exposure to oral S-ketamine is unaffected by itraconazole but greatly increased by ticlopidine. 2011 Aug 1
19 22023129 Inhibition of cytochrome P450 enzymes involved in ketamine metabolism by use of liver microsomes and specific cytochrome P450 enzymes from horses, dogs, and humans. 2011 Nov 2
20 20609441 Enantioselective capillary electrophoresis for identification and characterization of human cytochrome P450 enzymes which metabolize ketamine and norketamine in vitro. 2010 Dec 17 1
21 19442086 Polymorphic drug metabolism in anaesthesia. 2009 Mar 1
22 19702527 Substrate specificity, regulation, and polymorphism of human cytochrome P450 2B6. 2009 Sep 1
23 18781911 CYP2B6: new insights into a historically overlooked cytochrome P450 isozyme. 2008 Sep 1
24 17073575 The functional role of CYP2B6 in human drug metabolism: substrates and inhibitors in vitro, in vivo and in silico. 2006 Oct 1
25 12065445 Contribution of CYP3A4, CYP2B6, and CYP2C9 isoforms to N-demethylation of ketamine in human liver microsomes. 2002 Jul 3
26 11353758 Involvement of CYP2B6 in n-demethylation of ketamine in human liver microsomes. 2001 Jun 2