| 1 |
32817462 | Tyrosine Nitration Contributes to Nitric Oxide-Stimulated Degradation of CYP2B6. | 2020 Sep |
1 |
| 2 |
28724407 | Characterization of the cytochrome P450 monooxygenase genes (P450ome) from the carotenogenic yeast Xanthophyllomyces dendrorhous. | 2017 Jul 19 |
2 |
| 3 |
29018344 | Xanthates As Useful Probes for Testing the Active Sites of Cytochromes P450 4A11 and 2E1. | 2017 |
1 |
| 4 |
29156454 | Site-selective and stereoselective functionalization of non-activated tertiary C-H bonds. | 2017 Nov 30 |
1 |
| 5 |
27867424 | Aldehyde and Ketone Synthesis by P450-Catalyzed Oxidative Deamination of Alkyl Azides. | 2016 Aug 22 |
1 |
| 6 |
25498968 | Molecular mechanisms of the microsomal mixed function oxidases and biological and pathological implications. | 2015 |
2 |
| 7 |
25585967 | Structural and biophysical characterization of human cytochromes P450 2B6 and 2A6 bound to volatile hydrocarbons: analysis and comparison. | 2015 Apr |
1 |
| 8 |
26002739 | Mechanistic basis of electron transfer to cytochromes p450 by natural redox partners and artificial donor constructs. | 2015 |
1 |
| 9 |
26075493 | Mechanism-Based Inactivation of Human Cytochrome P450 2B6 by Chlorpyrifos. | 2015 Jul 20 |
1 |
| 10 |
23057845 | Mechanism of the plant cytochrome P450 for herbicide resistance: a modelling study. | 2013 Dec |
1 |
| 11 |
23886699 | The effect of ritonavir on human CYP2B6 catalytic activity: heme modification contributes to the mechanism-based inactivation of CYP2B6 and CYP3A4 by ritonavir. | 2013 Oct |
3 |
| 12 |
23905516 | Investigations of heme ligation and ligand switching in cytochromes p450 and p420. | 2013 Aug 27 |
1 |
| 13 |
22245335 | A novel type of allosteric regulation: functional cooperativity in monomeric proteins. | 2012 Mar 15 |
2 |
| 14 |
22573452 | Cryoradiolysis and cryospectroscopy for studies of heme-oxygen intermediates in cytochromes p450. | 2012 |
1 |
| 15 |
22685215 | Mechanism-based inactivation of cytochrome P450 2B6 by methadone through destruction of prosthetic heme. | 2012 Sep |
4 |
| 16 |
21659470 | Polymorphic variants of cytochrome P450 2B6 (CYP2B6.4-CYP2B6.9) exhibit altered rates of metabolism for bupropion and efavirenz: a charge-reversal mutation in the K139E variant (CYP2B6.8) impairs formation of a functional cytochrome p450-reductase complex. | 2011 Sep |
1 |
| 17 |
21862689 | Mechanism-based inactivation of human cytochrome P450 2B6 by clopidogrel: involvement of both covalent modification of cysteinyl residue 475 and loss of heme. | 2011 Nov |
3 |
| 18 |
21930824 | Thr302 is the site for the covalent modification of human cytochrome P450 2B6 leading to mechanism-based inactivation by tert-butylphenylacetylene. | 2011 Dec |
1 |
| 19 |
19944064 | Rational engineering of cytochromes P450 2B6 and 2B11 for enhanced stability: Insights into structural importance of residue 334. | 2010 Feb 15 |
1 |
| 20 |
19947890 | New cytochrome P450 mechanisms: implications for understanding molecular basis for drug toxicity at the level of the cytochrome. | 2010 Jan |
1 |
| 21 |
20501634 | The effects of azole-based heme oxygenase inhibitors on rat cytochromes P450 2E1 and 3A1/2 and human cytochromes P450 3A4 and 2D6. | 2010 Sep 1 |
2 |
| 22 |
19168709 | Metabolic activation of mifepristone [RU486; 17beta-hydroxy-11beta-(4-dimethylaminophenyl)-17alpha-(1-propynyl)-estra-4,9-dien-3-one] by mammalian cytochromes P450 and the mechanism-based inactivation of human CYP2B6. | 2009 Apr |
1 |
| 23 |
18164676 | Electrochemistry of cytochrome P450 enzyme on nanoparticle-containing membrane-coated electrode and its applications for drug sensing. | 2008 Apr 15 |
1 |
| 24 |
18478283 | Comparing the electronic properties and docking calculations of heme derivatives on CYP2B4. | 2008 Jun |
2 |
| 25 |
18563875 | How do azoles inhibit cytochrome P450 enzymes? A density functional study. | 2008 Dec 18 |
6 |
| 26 |
18642140 | Mechanism and role of covalent heme binding in the CYP4 family of P450 enzymes and the mammalian peroxidases. | 2008 |
2 |
| 27 |
18976212 | New findings in studies of cytochromes P450. | 2008 Sep |
1 |
| 28 |
17123739 | Structural analysis of cytochromes P450 shows differences in flexibility of heme 2- and 4-vinyls. | 2007 Mar |
3 |
| 29 |
17504219 | Expression and function of cytochrome p450 in brain drug metabolism. | 2007 May |
1 |
| 30 |
17584015 | Mechanism-based inactivation of cytochrome P450 enzymes: chemical mechanisms, structure-activity relationships and relationship to clinical drug-drug interactions and idiosyncratic adverse drug reactions. | 2007 Jun |
2 |
| 31 |
17907788 | Peroxynitrite inactivation of human cytochrome P450s 2B6 and 2E1: heme modification and site-specific nitrotyrosine formation. | 2007 Nov |
1 |
| 32 |
16882766 | Synthesis of substituted phenyl diaziridines and characterization as mechanism-based inactivators of human cytochrome P450 2B6. | 2006 Nov |
7 |
| 33 |
17180920 | [Nanoelectrochemistry of cytochrome P450s: direct electron transfer and electrocatalysis]. | 2006 Sep-Oct |
1 |
| 34 |
17216026 | Progress towards the easier use of P450 enzymes. | 2006 Oct |
1 |
| 35 |
15651036 | Prediction of binding modes for ligands in the cytochromes P450 and other heme-containing proteins. | 2005 Mar 1 |
1 |
| 36 |
15746946 | A virus-directed enzyme prodrug therapy (VDEPT) strategy for lung cancer using a CYP2B6/NADPH-cytochrome P450 reductase fusion protein. | 2005 May |
1 |
| 37 |
15822184 | Cytochrome P450 ubiquitination: branding for the proteolytic slaughter? | 2005 |
1 |
| 38 |
16010857 | Developmental pharmacology and toxicology: biotransformation of drugs and other xenobiotics during postnatal development. | 2005 Jan-Jun |
1 |
| 39 |
15081898 | The mechanism-based inactivation of p450 2B4 by tert-butyl 1-methyl-2-propynyl ether: structural determination of the adducts to the p450 heme. | 2004 May 1 |
4 |
| 40 |
12975333 | In vitro metabolism studies on the isoxazole ring scission in the anti-inflammatory agent lefluonomide to its active alpha-cyanoenol metabolite A771726: mechanistic similarities with the cytochrome P450-catalyzed dehydration of aldoximes. | 2003 Oct |
1 |
| 41 |
14563924 | An open conformation of mammalian cytochrome P450 2B4 at 1.6-A resolution. | 2003 Nov 11 |
1 |
| 42 |
11933021 | Nonsteroidal aromatase inhibitors: recent advances. | 2002 May |
1 |
| 43 |
12391268 | Cytochrome P450 CYP1A1 accumulates in the cytosol of kidney and brain and is activated by heme. | 2002 Nov |
1 |
| 44 |
11908754 | Recent advances in P450 research. | 2001 |
1 |
| 45 |
10698112 | Cytochrome P450 catalyzed nitric oxide synthesis: a theoretical study. | 2000 Feb |
1 |
| 46 |
10867234 | Cloning, sequencing, and expression in Escherichia coli of a cytochrome P450 gene from Cunninghamella elegans. | 2000 Jul 1 |
2 |
| 47 |
10888271 | Interaction of histamine and other bioamines with cytochromes P450: implications for cell growth modulation and chemopotentiation by drugs. | 2000 Feb |
1 |
| 48 |
11097178 | Structural similarities and differences of the heme pockets of various P450 isoforms as revealed by resonance Raman spectroscopy. | 2000 Nov 1 |
2 |
| 49 |
9888815 | Dynamics of protein-bound water in the heme domain of P450BM3 studied by high-pressure spectroscopy: comparison with P450cam and P450 2B4. | 1999 Jan 12 |
1 |
| 50 |
10557259 | Optical detection of cytochrome P450 by sensitizer-linked substrates. | 1999 Nov 9 |
2 |