sibutramine

cytochrome P450 family 2 subfamily B member 6 ; Homo sapiens







11 Article(s)
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1 32970826 Clopidogrel Dosing: Current Successes and Emerging Factors for Further Consideration. 2021 May 1
2 24262967 Effects of CYP3A5, CYP2C19, and CYP2B6 on the clinical efficacy and adverse outcomes of sibutramine therapy: a crucial role for the CYP2B6*6 allele. 2014 Jan 20 3
3 25343291 Enantioselective N-demethylation and hydroxylation of sibutramine in human liver microsomes and recombinant cytochrome p-450 isoforms. 2014 1
4 22830954 Effects of clopidogrel and clarithromycin on the disposition of sibutramine and its active metabolites M1 and M2 in relation to CYP2B6*6 polymorphism. 2013 Feb 4
5 23381968 Different effects of clopidogrel and clarithromycin on the enantioselective pharmacokinetics of sibutramine and its active metabolites in healthy subjects. 2013 May 3
6 23777987 Potent inhibition of cytochrome P450 2B6 by sibutramine in human liver microsomes. 2013 Sep 5 7
7 20350955 Effect of CYP2B6 genotype on the pharmacokinetics of sibutramine and active metabolites in healthy subjects. 2011 Jan 3
8 21209232 Effects of clopidogrel on the pharmacokinetics of sibutramine and its active metabolites. 2011 Dec 6
9 19693007 Association of CYP2B6, CYP3A5, and CYP2C19 genetic polymorphisms with sibutramine pharmacokinetics in healthy Korean subjects. 2009 Nov 2
10 19702527 Substrate specificity, regulation, and polymorphism of human cytochrome P450 2B6. 2009 Sep 1
11 18474675 Cytochrome P450 2B6 catalyzes the formation of pharmacologically active sibutramine (N-{1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl}-N,N-dimethylamine) metabolites in human liver microsomes. 2008 Aug 7