Nevirapine

cytochrome P450 family 2 subfamily B member 6 ; Homo sapiens







43 Article(s)
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1 35484635 Trough plasma nevirapine levels, immunologic and virologic responses in composite CYP2B6*6/*18 HIV-infected adult Nigerian patients. 2022 Jul 2
2 35512066 The role of CYP2B6 516G>T polymorphism on efavirenz/nevirapine toxicity. Implications on treatment outcomes: Lessons from Botswana. 2022 Apr 29 1
3 32815870 Pharmacogenetic interactions of rifapentine plus isoniazid with efavirenz or nevirapine. 2021 Jan 1
4 33758532 Association of CYP2B6 Genetic Variation with Efavirenz and Nevirapine Drug Resistance in HIV-1 Patients from Botswana. 2021 3
5 33833550 Erratum: Association of CYP2B6 Genetic Variation with Efavirenz and Nevirapine Drug Resistance in HIV-1 Patients from Botswana [Corrigendum]. 2021 1
6 33060725 Effects of CYP2B6 polymorphisms on plasma nevirapine concentrations: a systematic review and meta-analysis. 2020 Oct 15 3
7 30864294 Occurrence of CYP2B6 516G>T polymorphism in patients with ARV-associated hepatotoxicity. 2019 Apr 4
8 27707991 Effect of diurnal variation, CYP2B6 genotype and age on the pharmacokinetics of nevirapine in African children. 2017 Jan 1
9 28187506 The Effect of Gene Variants on Levonorgestrel Pharmacokinetics When Combined With Antiretroviral Therapy Containing Efavirenz or Nevirapine. 2017 Sep 1
10 26626330 Transcriptional profiling suggests that Nevirapine and Ritonavir cause drug induced liver injury through distinct mechanisms in primary human hepatocytes. 2016 Aug 5 1
11 26891286 Inhibition of CYP2B6 by Medicinal Plant Extracts: Implication for Use of Efavirenz and Nevirapine-Based Highly Active Anti-Retroviral Therapy (HAART) in Resource-Limited Settings. 2016 Feb 16 1
12 27195527 Pregnancy affects nevirapine pharmacokinetics: evidence from a CYP2B6 genotype-guided observational study. 2016 Aug 2
13 27709010 Insights into CYP2B6-mediated drug-drug interactions. 2016 Sep 1
14 25878720 Cytochrome P450 2B6 genetic variants are associated with plasma nevirapine levels and clinical response in HIV-1 infected Kenyan women: a prospective cohort study. 2015 6
15 26247717 CYP2B6 poor metaboliser alleles involved in efavirenz and nevirapine metabolism: CYP2B6*9 and CYP2B6*18 distribution in HIV-exposed subjects from Dschang, Western Cameroon. 2015 Oct 1
16 26348712 Effects of CYP2B6 and CYP1A2 Genetic Variation on Nevirapine Plasma Concentration and Pharmacodynamics as Measured by CD4 Cell Count in Zimbabwean HIV-Infected Patients. 2015 Sep 5
17 26415139 A Global Health Diagnostic for Personalized Medicine in Resource-Constrained World Settings: A Simple PCR-RFLP Method for Genotyping CYP2B6 g.15582C>T and Science and Policy Relevance for Optimal Use of Antiretroviral Drug Efavirenz. 2015 Jun 1
18 23687222 Clinical and genetic determinants of plasma nevirapine exposure following an intrapartum dose to prevent mother-to-child HIV transmission. 2013 Aug 15 2
19 23774940 Association between CYP2B6 polymorphisms and Nevirapine-induced SJS/TEN: a pharmacogenetics study. 2013 Nov 1
20 23982262 Measuring the overall genetic component of nevirapine pharmacokinetics and the role of selected polymorphisms: towards addressing the missing heritability in pharmacogenetic phenotypes? 2013 Nov 1
21 24517233 Genetic variants of drug metabolizing enzymes and drug transporter (ABCB1) as possible biomarkers for adverse drug reactions in an HIV/AIDS cohort in Zimbabwe. 2013 Sep 1
22 22082652 Association of ABCC10 polymorphisms with nevirapine plasma concentrations in the German Competence Network for HIV/AIDS. 2012 Jan 1
23 22111602 Exploration of CYP450 and drug transporter genotypes and correlations with nevirapine exposure in Malawians. 2012 Jan 2
24 22462748 Worldwide variation in human drug-metabolism enzyme genes CYP2B6 and UGT2B7: implications for HIV/AIDS treatment. 2012 Apr 1
25 22680342 Influence of CYP2B6 and ABCB1 SNPs on nevirapine plasma concentrations in Burundese HIV-positive patients using dried sample spot devices. 2012 Jul 3
26 23104099 Multiple genetic variants predict steady-state nevirapine clearance in HIV-infected Cambodians. 2012 Dec 2
27 23439719 Clinical perspectives on human genetic screening to prevent nevirapine toxicity. 2012 Sep 1 1
28 21393201 Factors influencing plasma nevirapine levels: a study in HIV-infected children on generic antiretroviral treatment in India. 2011 Jun 1
29 21441248 Integration of population pharmacokinetics and pharmacogenetics: an aid to optimal nevirapine dose selection in HIV-infected individuals. 2011 Jun 3
30 21860339 Integration of absorption, distribution, metabolism, and elimination genotyping data into a population pharmacokinetic analysis of nevirapine. 2011 Nov 1
31 20338069 Effects of CYP2B6 G516T polymorphisms on plasma efavirenz and nevirapine levels when co-administered with rifampicin in HIV/TB co-infected Thai adults. 2010 Mar 26 4
32 19228205 Cytochrome P450 2B6 516G-->T is associated with plasma concentrations of nevirapine at both 200 mg twice daily and 400 mg once daily in an ethnically diverse population. 2009 May 4
33 19239339 Associations between CYP2B6 polymorphisms and pharmacokinetics after a single dose of nevirapine or efavirenz in African americans. 2009 Mar 15 2
34 19702527 Substrate specificity, regulation, and polymorphism of human cytochrome P450 2B6. 2009 Sep 1
35 19812066 Influence of CYP2B6 polymorphisms on the persistence of plasma nevirapine concentrations following a single intra-partum dose for the prevention of mother to child transmission in HIV-infected Thai women. 2009 Dec 2
36 18281305 Impact of CYP2B6 983T>C polymorphism on non-nucleoside reverse transcriptase inhibitor plasma concentrations in HIV-infected patients. 2008 Apr 1
37 18781911 CYP2B6: new insights into a historically overlooked cytochrome P450 isozyme. 2008 Sep 1
38 21197270 Effect of Host Genetic Variation on the Pharmacokinetics and Clinical Response of Non-nucleoside Reverse Transcriptase Inhibitors. 2008 Jan 1 1
39 17352764 Cytochrome P450 2B6 (CYP2B6) G516T influences nevirapine plasma concentrations in HIV-infected patients in Uganda. 2007 Mar 1
40 18090046 CYP2B6 genetic variants are associated with nevirapine pharmacokinetics and clinical response in HIV-1-infected children. 2007 Oct 18 4
41 17003847 RAT CYP3A and CYP2B1/2 were not associated with nevirapine-induced hepatotoxicity. 2006 Sep 2
42 15864119 Influence of CYP2B6 polymorphism on plasma and intracellular concentrations and toxicity of efavirenz and nevirapine in HIV-infected patients. 2005 Jan 2
43 14628297 Stereoselective metabolism of methadone N-demethylation by cytochrome P4502B6 and 2C19. 2004 Jan 1