coumarin

cytochrome P450 family 2 subfamily B member 6 ; Homo sapiens







15 Article(s)
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1 23648676 Cytochrome P450 metabolic activities in the small intestine of cynomolgus macaques bred in Cambodia, China, and Indonesia. 2013 1
2 20100815 Engineering bacterial cytochrome P450 (P450) BM3 into a prototype with human P450 enzyme activity using indigo formation. 2010 May 2
3 19168709 Metabolic activation of mifepristone [RU486; 17beta-hydroxy-11beta-(4-dimethylaminophenyl)-17alpha-(1-propynyl)-estra-4,9-dien-3-one] by mammalian cytochromes P450 and the mechanism-based inactivation of human CYP2B6. 2009 Apr 1
4 19745566 Cytochrome P450-dependent drug oxidation activity of liver microsomes from Microminipigs, a possible new animal model for humans in non-clinical studies. 2009 1
5 15155554 Selective inhibition of CYP2B6-catalyzed bupropion hydroxylation in human liver microsomes in vitro. 2004 Jun 1
6 11181500 P450 enzyme expression patterns in the NCI human tumor cell line panel. 2001 Mar 1
7 9918546 Biotransformation of coumarin by rodent and human cytochromes P-450: metabolic basis of tissue-selective toxicity in olfactory mucosa of rats and mice. 1999 Feb 2
8 10027632 Highly sensitive high-performance liquid chromatographic assay for coumarin 7-hydroxylation and 7-ethoxycoumarin O-deethylation by human liver cytochrome P450 enzymes. 1999 Jan 8 4
9 10350185 Roles of CYP2A6 and CYP2B6 in nicotine C-oxidation by human liver microsomes. 1999 Mar 1
10 9394031 Mechanism-based inactivation of human liver cytochrome P450 2A6 by 8-methoxypsoralen. 1997 Dec 1
11 8806763 Kinetic analysis of the activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by heterologously expressed human P450 enzymes and the effect of P450-specific chemical inhibitors on this activation in human liver microsomes. 1996 Sep 1 2
12 8819299 Specificity of substrate and inhibitor probes for cytochrome P450s: evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes. 1996 Jul 1
13 8220911 Human liver microsomal metabolism of the enantiomers of warfarin and acenocoumarol: P450 isozyme diversity determines the differences in their pharmacokinetics. 1993 Sep 1
14 1423839 Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes. 1992 Oct 1
15 3378062 [Isolation and characteristics of coumarin-specific cytochrome P-450 (P-450Cho) from liver microsomes of DBA/2N mice, induced with pyrazole]. 1988 Mar 2