NADP

cytochrome P450 family 2 subfamily B member 6 ; Homo sapiens







40 Article(s)
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1 31001351 Inhibition of Cytochrome P450 Activities by Sophora flavescens Extract and Its Prenylated Flavonoids in Human Liver Microsomes. 2019 1
2 28288493 Inhibitory Effects of Garcinia cambogia Extract on CYP2B6 Enzyme Activity. 2017 Jul 1
3 29148818 Dissociation Constants of Cytochrome P450 2C9/Cytochrome P450 Reductase Complexes in a Lipid Bilayer Membrane Depend on NADPH: A Single-Protein Tracking Study. 2017 Dec 13 1
4 25378064 Imperatorin is a mechanism-based inactivator of CYP2B6. 2015 Jan 1
5 26335194 Psoralen, a mechanism-based inactivator of CYP2B6. 2015 Oct 5 3
6 22085411 Photoregulation of cytochrome P450 activity by using caged compound. 2012 Jan 3 3
7 22685215 Mechanism-based inactivation of cytochrome P450 2B6 by methadone through destruction of prosthetic heme. 2012 Sep 2
8 20851096 Oxygen activation by P450(cin): Protein and substrate mutagenesis. 2011 Mar 1 1
9 21659470 Polymorphic variants of cytochrome P450 2B6 (CYP2B6.4-CYP2B6.9) exhibit altered rates of metabolism for bupropion and efavirenz: a charge-reversal mutation in the K139E variant (CYP2B6.8) impairs formation of a functional cytochrome p450-reductase complex. 2011 Sep 2
10 21930824 Thr302 is the site for the covalent modification of human cytochrome P450 2B6 leading to mechanism-based inactivation by tert-butylphenylacetylene. 2011 Dec 1
11 20849814 Reduction in hepatic drug metabolizing CYP3A4 activities caused by P450 oxidoreductase mutations identified in patients with disordered steroid metabolism. 2010 Oct 8 2
12 19171677 Electrocatalytic drug metabolism by CYP2C9 bonded to a self-assembled monolayer-modified electrode. 2009 Apr 1
13 17213193 Cooperativity in cytochrome P450 3A4: linkages in substrate binding, spin state, uncoupling, and product formation. 2007 Mar 9 1
14 17693640 Cytochrome b5 increases the rate of product formation by cytochrome P450 2B4 and competes with cytochrome P450 reductase for a binding site on cytochrome P450 2B4. 2007 Oct 12 1
15 16882766 Synthesis of substituted phenyl diaziridines and characterization as mechanism-based inactivators of human cytochrome P450 2B6. 2006 Nov 1
16 16959210 Cysteine 98 in CYP3A4 contributes to conformational integrity required for P450 interaction with CYP reductase. 2006 Oct 1 1
17 15652242 Inhibition of human CYP2B6 by N,N',N''-triethylenethiophosphoramide is irreversible and mechanism-based. 2005 Feb 1 1
18 15774560 Minireview: regulation of steroidogenesis by electron transfer. 2005 Jun 1
19 14563790 Potent mechanism-based inhibition of human CYP2B6 by clopidogrel and ticlopidine. 2004 Jan 1
20 15081898 The mechanism-based inactivation of p450 2B4 by tert-butyl 1-methyl-2-propynyl ether: structural determination of the adducts to the p450 heme. 2004 May 1 1
21 15089095 Formation and reduction of aryl and heterocyclic nitroso compounds and significance in the flux of hydroxylamines. 2004 Apr 3
22 12485952 The mechanism-based inactivation of human cytochrome P450 2B6 by phencyclidine. 2003 Jan 1
23 12527701 Comparison of the formation of N-alkylprotoporphyrin IX after interaction of porphyrinogenic xenobiotics with single cDNA-expressed human P450 enzymes in microsomes prepared from baculovirus-infected insect cells and human lymphoblastoid cell lines. 2003 Feb 1
24 12725870 Organization of multiple cytochrome P450s with NADPH-cytochrome P450 reductase in membranes. 2003 May 1
25 12920169 Biotransformation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in peripheral human lung microsomes. 2003 Sep 3
26 11684365 Neoantigen formation and clastogenic action of HCFC-123 and perchloroethylene in human MCL-5 cells. 2001 Oct 15 1
27 15012237 MOLECULAR-GENETIC ANALYSIS OF PLANT CYTOCHROME P450-DEPENDENT MONOOXYGENASES. 1998 Jun 1
28 9046019 NADPH-initiated cytochrome P450-dependent free iron-independent microsomal lipid peroxidation: specific prevention by ascorbic acid. 1997 Jan 1
29 9179987 Molecular modelling of mammalian CYP2B isoforms and their interaction with substrates, inhibitors and redox partners. 1997 May 2
30 7788866 Non-specific inhibition of cytochrome P450 activities by chlorophyllin in human and rat liver microsomes. 1995 Jun 2
31 7819404 [Uncoupling of the liver monooxygenase system by perfluorocarbons in vivo]. 1994 Aug 1
32 8323289 Role of lysine and arginine residues of cytochrome P450 in the interaction between cytochrome P4502B1 and NADPH-cytochrome P450 reductase. 1993 Jul 4
33 8460938 Purification of multiple forms of cytochrome P450 from a human brain and reconstitution of catalytic activities. 1993 Mar 1
34 1349603 Electrostatic interactions stabilizing ferredoxin electron transfer complexes. Disruption by "conservative" mutations. 1992 May 5 1
35 16668240 Multiple forms of plant cytochromes p-450. 1991 Jul 1
36 2856164 Cytochrome-P-450-dependent metabolism of retinoic acid in rat skin microsomes: inhibition by ketoconazole. 1988 1
37 3304205 Alcohol-inducible cytochrome P-450 (P-450ALC). 1987 4
38 6489339 Mechanism of rate control of the NADPH-dependent reduction of cytochrome P-450 by lipids in reconstituted phospholipid vesicles. 1984 Nov 2 2
39 6416251 Kinetics of elementary steps in the cytochrome P-450 reaction sequence. VI. Model treatment of the NADPH-dependent first electron transfer reaction between cytochrome P-450 reductase and cytochrome P-450 LM2 in solution. 1983 1
40 4156173 Liver microsomal electron transport systems. III. The involvement of cytochrome b5 in the NADPH-supported cytochrome P-450-dependent hydroxylation of chlorobenzene. 1974 Dec 23 1