| 1 |
35062050 | CYP450 drug inducibility in NAFLD via an in vitro hepatic model: Understanding drug-drug interactions in the fatty liver. | 2022 Feb |
1 |
| 2 |
33806634 | Physiologically Based Pharmacokinetic Modeling of Bupropion and Its Metabolites in a CYP2B6 Drug-Drug-Gene Interaction Network. | 2021 Mar 4 |
1 |
| 3 |
32320483 | Clinically Relevant Cytochrome P450 3A4 Induction Mechanisms and Drug Screening in Three-Dimensional Spheroid Cultures of Primary Human Hepatocytes. | 2020 Oct |
1 |
| 4 |
31526233 | MicroRNA Mediated Changes in Drug Metabolism and Target Gene Expression by Efavirenz and Rifampicin In Vitro: Clinical Implications. | 2019 Oct |
1 |
| 5 |
28403028 | Compatibility of next-generation first-line antiretrovirals with rifampicin-based antituberculosis therapy in resource limited settings. | 2017 Jul |
2 |
| 6 |
28819225 | Cytochrome P450/ABC transporter inhibition simultaneously enhances ivermectin pharmacokinetics in the mammal host and pharmacodynamics in Anopheles gambiae. | 2017 Aug 17 |
1 |
| 7 |
28945086 | Oleanolic Acid-Mediated Inhibition of Pregnane X Receptor and Constitutive Androstane Receptor Attenuates Rifampin-Isoniazid Cytotoxicity. | 2017 Oct 4 |
2 |
| 8 |
29157826 | Modulation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation by ursolic acid (UA) attenuates rifampin-isoniazid cytotoxicity. | 2017 Dec 1 |
2 |
| 9 |
27045425 | CYP2B6 genotype-based efavirenz dose recommendations during rifampicin-based antituberculosis cotreatment for a sub-Saharan Africa population. | 2016 Apr |
1 |
| 10 |
27311985 | MicroRNA hsa-miR-25-3p suppresses the expression and drug induction of CYP2B6 in human hepatocytes. | 2016 Aug 1 |
1 |
| 11 |
27917125 | Comparison of Liver Cell Models Using the Basel Phenotyping Cocktail. | 2016 |
1 |
| 12 |
25600204 | Human HepaRG Cells can be Cultured in Hanging-drop Plates for Cytochrome P450 Induction and Function Assays. | 2015 |
1 |
| 13 |
26516577 | Applicability of second-generation upcyte® human hepatocytes for use in CYP inhibition and induction studies. | 2015 Oct |
1 |
| 14 |
23990572 | Dependence of efavirenz- and rifampicin-isoniazid-based antituberculosis treatment drug-drug interaction on CYP2B6 and NAT2 genetic polymorphisms: ANRS 12154 study in Cambodia. | 2014 Feb 1 |
1 |
| 15 |
24316028 | The role of genetic polymorphisms in cytochrome P450 and effects of tuberculosis co-treatment on the predictive value of CYP2B6 SNPs and on efavirenz plasma levels in adult HIV patients. | 2014 Feb |
1 |
| 16 |
24553381 | Evaluation of 23 lots of commercially available cryopreserved hepatocytes for induction assays of human cytochromes P450. | 2014 May |
1 |
| 17 |
24820076 | Isoniazid mediates the CYP2B6*6 genotype-dependent interaction between efavirenz and antituberculosis drug therapy through mechanism-based inactivation of CYP2A6. | 2014 Jul |
1 |
| 18 |
23935064 | Regulation of microRNA expression by rifampin in human hepatocytes. | 2013 Oct |
6 |
| 19 |
24180002 | Effects of rifampin-based antituberculosis therapy on plasma efavirenz concentrations in children vary by CYP2B6 genotype. | 2013 Jul 31 |
2 |
| 20 |
20876786 | Effects of pregnane X receptor (NR1I2) and CYP2B6 genetic polymorphisms on the induction of bupropion hydroxylation by rifampin. | 2011 Jan |
3 |
| 21 |
21111054 | Simultaneous assessment of cytochrome P450 activity in cultured human hepatocytes for compound-mediated induction of CYP3A4, CYP2B6, and CYP1A2. | 2011 May-Jun |
1 |
| 22 |
21150552 | Paradoxically elevated efavirenz concentrations in HIV/tuberculosis-coinfected patients with CYP2B6 516TT genotype on rifampin-containing antituberculous therapy. | 2011 Jan 28 |
2 |
| 23 |
21395646 | In silico prediction of efavirenz and rifampicin drug-drug interaction considering weight and CYP2B6 phenotype. | 2011 Apr |
2 |
| 24 |
21436404 | Cytochrome P450-dependent metabolism in HepaRG cells cultured in a dynamic three-dimensional bioreactor. | 2011 Jul |
1 |
| 25 |
21508826 | Effect of rifampicin on S-ketamine and S-norketamine plasma concentrations in healthy volunteers after intravenous S-ketamine administration. | 2011 Jun |
1 |
| 26 |
21930825 | Complex drug interactions of HIV protease inhibitors 2: in vivo induction and in vitro to in vivo correlation of induction of cytochrome P450 1A2, 2B6, and 2C9 by ritonavir or nelfinavir. | 2011 Dec |
1 |
| 27 |
20019244 | Stable expression, activity, and inducibility of cytochromes P450 in differentiated HepaRG cells. | 2010 Mar |
2 |
| 28 |
20338069 | Effects of CYP2B6 G516T polymorphisms on plasma efavirenz and nevirapine levels when co-administered with rifampicin in HIV/TB co-infected Thai adults. | 2010 Mar 26 |
1 |
| 29 |
20583967 | A multi-endpoint evaluation of cytochrome P450 1A2, 2B6 and 3A4 induction response in human hepatocyte cultures after treatment with β-naphthoflavone, phenobarbital and rifampicin. | 2010 Dec |
1 |
| 30 |
20624854 | Synergistically enhanced CYP2B6 inducibility between a polymorphic mutation in CYP2B6 promoter and pregnane X receptor activation. | 2010 Oct |
2 |
| 31 |
20642445 | Induction of CYP2B6 and CYP3A4 expression by 1-aminobenzotriazole (ABT) in human hepatocytes. | 2010 Aug |
1 |
| 32 |
19223781 | Effect of rifampicin on efavirenz pharmacokinetics in HIV-infected children with tuberculosis. | 2009 Apr 15 |
1 |
| 33 |
19520773 | Methadone induces the expression of hepatic drug-metabolizing enzymes through the activation of pregnane X receptor and constitutive androstane receptor. | 2009 Sep |
1 |
| 34 |
19704172 | Effect of rifampicin-based antitubercular therapy and the cytochrome P450 2B6 516G>T polymorphism on efavirenz concentrations in adults in South Africa. | 2009 |
2 |
| 35 |
18094037 | Induction of metabolism and transport in human intestine: validation of precision-cut slices as a tool to study induction of drug metabolism in human intestine in vitro. | 2008 Mar |
2 |
| 36 |
18728241 | Pharmacokinetics of efavirenz when co-administered with rifampin in TB/HIV co-infected patients: pharmacogenetic effect of CYP2B6 variation. | 2008 Sep |
1 |
| 37 |
17259447 | Enantiomeric metabolic interactions and stereoselective human methadone metabolism. | 2007 Apr |
1 |
| 38 |
16135659 | Simultaneous measurement of 23 isoforms from the human cytochrome P450 families 1 to 3 by quantitative reverse transcriptase-polymerase chain reaction. | 2005 Dec |
1 |
| 39 |
14977870 | Regulation of CYP2B6 in primary human hepatocytes by prototypical inducers. | 2004 Mar |
3 |
| 40 |
15364537 | The effects of gender, age, ethnicity, and liver cirrhosis on cytochrome P450 enzyme activity in human liver microsomes and inducibility in cultured human hepatocytes. | 2004 Sep 15 |
1 |
| 41 |
12695351 | Glucocorticoid receptor enhancement of pregnane X receptor-mediated CYP2B6 regulation in primary human hepatocytes. | 2003 May |
1 |
| 42 |
12815172 | Colchicine down-regulates cytochrome P450 2B6, 2C8, 2C9, and 3A4 in human hepatocytes by affecting their glucocorticoid receptor-mediated regulation. | 2003 Jul |
1 |
| 43 |
14604466 | Effect of bupropion on CYP2B6 and CYP3A4 catalytic activity, immunoreactive protein and mRNA levels in primary human hepatocytes: comparison with rifampicin. | 2003 Sep |
1 |
| 44 |
12040753 | Evaluation of gene induction of drug-metabolizing enzymes and transporters in primary culture of human hepatocytes using high-sensitivity real-time reverse transcription PCR. | 2002 May |
1 |
| 45 |
11181490 | Induction of CYP2C genes in human hepatocytes in primary culture. | 2001 Mar |
2 |
| 46 |
11257517 | Assessment of P450 induction in the marmoset monkey using targeted anti-peptide antibodies. | 2001 Mar 9 |
1 |
| 47 |
11502872 | Regulation of the human CYP2B6 gene by the nuclear pregnane X receptor. | 2001 Sep |
1 |
| 48 |
11503007 | Modulation of the cytochrome P450-mediated metabolism of ifosfamide by ketoconazole and rifampin. | 2001 Aug |
1 |
| 49 |
11714868 | Rifampin is a selective, pleiotropic inducer of drug metabolism genes in human hepatocytes: studies with cDNA and oligonucleotide expression arrays. | 2001 Dec |
1 |
| 50 |
10729196 | Quantitative RT-PCR measurement of human cytochrome P-450s: application to drug induction studies. | 2000 Apr 1 |
2 |