Ketoconazole

cytochrome P450 family 2 subfamily B member 6 ; Homo sapiens







22 Article(s)
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1 29671087 Severe Adverse Reactions Following Ketoconazole, Fluconazole, and Environmental Exposures: A Case Report. 2018 Apr 18 1
2 28340497 P450 inhibitor ketoconazole increased the intratumor drug levels and antitumor activity of fenretinide in human neuroblastoma xenograft models. 2017 Jul 15 2
3 25868557 Azole antifungal inhibition of buprenorphine, methadone and oxycodone in vitro metabolism. 2015 Jun 1
4 25429674 Drug interactions between nine antifungal agents and drugs metabolized by human cytochromes P450. 2014 1
5 22022918 Ilaprazole, a new proton pump inhibitor, is primarily metabolized to ilaprazole sulfone by CYP3A4 and 3A5. 2012 Mar 1
6 21550074 Ritonavir inhibits the two main prasugrel bioactivation pathways in vitro: a potential drug-drug interaction in HIV patients. 2011 Nov 1
7 20149798 Structural basis of human CYP51 inhibition by antifungal azoles. 2010 Apr 9 1
8 17020957 A novel model for the prediction of drug-drug interactions in humans based on in vitro cytochrome p450 phenotypic data. 2007 Jan 3
9 17376532 Electrochemical properties of cytochroms P450 using nanostructured electrodes: direct electron transfer and electro catalysis. 2007 May 1
10 16855053 Metabolism of endosulfan-alpha by human liver microsomes and its utility as a simultaneous in vitro probe for CYP2B6 and CYP3A4. 2006 Oct 1
11 14709627 Highly selective inhibition of human CYP3Aa in vitro by azamulin and evidence that inhibition is irreversible. 2004 Jan 1
12 15319333 CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes. 2004 Sep 1
13 12433801 Involvement of CYP3A in the metabolism of eplerenone in humans and dogs: differential metabolism by CYP3A4 and CYP3A5. 2002 Dec 1
14 11469860 Ketoconazole-induced conformational changes in the active site of cytochrome P450eryF. 2001 Aug 3 2
15 11503007 Modulation of the cytochrome P450-mediated metabolism of ifosfamide by ketoconazole and rifampin. 2001 Aug 1
16 11710930 UVB-induced conversion of 7-dehydrocholesterol to 1alpha,25-dihydroxyvitamin D3 in an in vitro human skin equivalent model. 2001 Nov 1
17 11140269 UVB-induced conversion of 7-dehydrocholesterol to 1 alpha,25-dihydroxyvitamin D3 (calcitriol) in the human keratinocyte line HaCaT. 2000 Dec 1
18 9925971 In vitro biotransformation of a novel antimalarial cysteine protease inhibitor in human liver microsomes. 1999 Mar 1
19 8578771 Drug toxicity mechanisms in human hepatoma HepG2 cells: cyclosporin A and tamoxifen. 1995 Nov 1
20 1598960 Combined use of cyclosporine and ketoconazole in the treatment of endogenous uveitis. 1992 Jun 15 1
21 2856164 Cytochrome-P-450-dependent metabolism of retinoic acid in rat skin microsomes: inhibition by ketoconazole. 1988 1
22 3500726 Interactions of imidazole antifungal agents with purified cytochrome P-450 proteins. 1987 Dec 15 1