Ticlopidine

cytochrome P450 family 2 subfamily B member 6 ; Homo sapiens







19 Article(s)
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1 35246464 Estimation of Fraction Metabolized by Cytochrome P450 Enzymes Using Long-Term Cocultured Human Hepatocytes. 2022 May 1
2 28737446 Quantitative in vitro phenotyping and prediction of drug interaction potential of CYP2B6 substrates as victims. 2018 Jul 3
3 30091858 Semimechanistic Population Pharmacokinetic Model to Predict the Drug-Drug Interaction Between S-ketamine and Ticlopidine in Healthy Human Volunteers. 2018 Oct 2
4 25378064 Imperatorin is a mechanism-based inactivator of CYP2B6. 2015 Jan 1
5 26335194 Psoralen, a mechanism-based inactivator of CYP2B6. 2015 Oct 5 1
6 23099620 Ticlopidine inhibits both O-demethylation and renal clearance of tramadol, increasing the exposure to it, but itraconazole has no marked effect on the ticlopidine-tramadol interaction. 2013 Apr 2
7 23361846 Role of cytochrome P4502B6 in methadone metabolism and clearance. 2013 Mar 1
8 21156812 Comparison of in vitro metabolism of ticlopidine by human cytochrome P450 2B6 and rabbit cytochrome P450 2B4. 2011 Mar 1
9 21570381 Metabolism of bupropion by baboon hepatic and placental microsomes. 2011 Aug 1 1
10 21716267 Exposure to oral S-ketamine is unaffected by itraconazole but greatly increased by ticlopidine. 2011 Aug 1
11 20610889 Enhanced susceptibility of HLA-mediated ticlopidine-induced idiosyncratic hepatotoxicity by CYP2B6 polymorphism in Japanese. 2010 2
12 19047469 Mechanism-based inhibition of human cytochrome P450 2B6 by ticlopidine, clopidogrel, and the thiolactone metabolite of prasugrel. 2009 Mar 3
13 18474675 Cytochrome P450 2B6 catalyzes the formation of pharmacologically active sibutramine (N-{1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl}-N,N-dimethylamine) metabolites in human liver microsomes. 2008 Aug 1
14 19122335 Comparison of human cytochrome P450 inhibition by the thienopyridines prasugrel, clopidogrel, and ticlopidine. 2008 1
15 17682072 A comparison of 2-phenyl-2-(1-piperidinyl)propane (ppp), 1,1',1''-phosphinothioylidynetrisaziridine (thioTEPA), clopidogrel, and ticlopidine as selective inactivators of human cytochrome P450 2B6. 2007 Nov 1
16 16855053 Metabolism of endosulfan-alpha by human liver microsomes and its utility as a simultaneous in vitro probe for CYP2B6 and CYP3A4. 2006 Oct 2
17 17073575 The functional role of CYP2B6 in human drug metabolism: substrates and inhibitors in vitro, in vivo and in silico. 2006 Oct 1
18 15961986 Effect of clopidogrel and ticlopidine on cytochrome P450 2B6 activity as measured by bupropion hydroxylation. 2005 Jun 4
19 14563790 Potent mechanism-based inhibition of human CYP2B6 by clopidogrel and ticlopidine. 2004 Jan 2