Nicotine

cytochrome P450 family 2 subfamily B member 6 ; Homo sapiens







21 Article(s)
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PMID
Title
Pub. Year
#Total Relationships
1 34165800 The Role of Pharmacogenetics in Smoking. 2021 Sep 1
2 33329709 Effects of Genetic Polymorphisms of Drug Transporter ABCB1 (MDR1) and Cytochrome P450 Enzymes CYP2A6, CYP2B6 on Nicotine Addiction and Smoking Cessation. 2020 1
3 30906561 Nicotine oxidation by genetic variants of CYP2B6 and in human brain microsomes. 2019 Apr 12
4 27750412 Differences in Toxicological and Pharmacological Responses Mediated by Polymorphic Cytochromes P450 and Related Drug-Metabolizing Enzymes. 2017 Jan 17 1
5 25409894 Characterization of CYP2B6 in a CYP2B6-humanized mouse model: inducibility in the liver by phenobarbital and dexamethasone and role in nicotine metabolism in vivo. 2015 Feb 3
6 25489907 CYP2B6 gene single-nucleotide polymorphisms in an Italian population sample and relationship with nicotine dependence. 2015 Feb 8
7 25652250 Effect of Brain CYP2B Inhibition on Brain Nicotine Levels and Nicotine Self-Administration. 2015 Jul 10
8 25655887 Pharmacogenetics of nicotine and associated smoking behaviors. 2015 1
9 23591849 Pilot study of CYP2B6 genetic variation to explore the contribution of nitrosamine activation to lung carcinogenesis. 2013 Apr 16 1
10 23639433 Ethanol self-administration and nicotine treatment induce brain levels of CYP2B6 and CYP2E1 in African green monkeys. 2013 Sep 5
11 24260284 CYP2B6 non-coding variation associated with smoking cessation is also associated with differences in allelic expression, splicing, and nicotine metabolism independent of common amino-acid changes. 2013 4
12 22569203 CYP2A6 and CYP2B6 genetic variation and its association with nicotine metabolism in South Western Alaska Native people. 2012 Jun 3
13 21266057 Design, baseline characteristics, and retention of African American light smokers into a randomized trial involving biological data. 2011 Jan 25 1
14 20307138 Hepatic CYP2B6 is altered by genetic, physiologic, and environmental factors but plays little role in nicotine metabolism. 2010 Jun 1
15 16309716 CYP2B6 is expressed in African Green monkey brain and is induced by chronic nicotine treatment. 2006 Mar 8
16 16135656 CYP2A6 AND CYP2B6 are involved in nornicotine formation from nicotine in humans: interindividual differences in these contributions. 2005 Dec 3
17 15364541 PXR (NR1I2): splice variants in human tissues, including brain, and identification of neurosteroids and nicotine as PXR activators. 2004 Sep 15 1
18 12814665 Smoking, alcoholism and genetic polymorphisms alter CYP2B6 levels in human brain. 2003 Jul 3
19 12439223 Pharmacogenetic investigation of smoking cessation treatment. 2002 Nov 1
20 10350185 Roles of CYP2A6 and CYP2B6 in nicotine C-oxidation by human liver microsomes. 1999 Mar 3
21 1680658 Metabolism of nicotine by rat liver cytochromes P-450. Assessment utilizing monoclonal antibodies to nicotine and cotinine. 1991 Jul-Aug 5