Tricarboxylic Acids

succinate dehydrogenase complex iron sulfur subunit B ; Homo sapiens







43 Article(s)
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1 34871739 Identification of cyclin D1 as a major modulator of 3-nitropropionic acid-induced striatal neurodegeneration. 2022 Jan 2
2 35510387 Functional deficiency of succinate dehydrogenase promotes tumorigenesis and development of clear cell renal cell carcinoma through weakening of ferroptosis. 2022 Apr 4
3 31408429 Genetic, epigenetic and biochemical regulation of succinate dehydrogenase function. 2020 Feb 25 4
4 31914648 Succinate dehydrogenase deficiency in a chromaffin cell model retains metabolic fitness through the maintenance of mitochondrial NADH oxidoreductase function. 2020 Jan 1
5 32887801 The roles of SDHAF2 and dicarboxylate in covalent flavinylation of SDHA, the human complex II flavoprotein. 2020 Sep 22 4
6 33112834 Epigenetic and metabolic reprogramming of SDH-deficient paragangliomas. 2020 Dec 2
7 33153035 Succinate Dehydrogenase and Ribonucleic Acid Networks in Cancer and Other Diseases. 2020 Nov 3 4
8 30604579 Mitochondrial complex II of plants: subunit composition, assembly, and function in respiration and signaling. 2019 May 2
9 31236625 The assembly of succinate dehydrogenase: a key enzyme in bioenergetics. 2019 Oct 2
10 31564436 Distinct Alterations in Tricarboxylic Acid Cycle Metabolites Associate with Cancer and Autism Phenotypes in Cowden Syndrome and Bannayan-Riley-Ruvalcaba Syndrome. 2019 Oct 3 2
11 28423651 Succinate dehydrogenase B-deficient cancer cells are highly sensitive to bromodomain and extra-terminal inhibitors. 2017 Apr 25 2
12 28619735 The Evolving Role of Succinate in Tumor Metabolism: An 18F-FDG-Based Study. 2017 Nov 1
13 26697888 Cardiac-specific succinate dehydrogenase deficiency in Barth syndrome. 2016 Feb 1 2
14 27493882 Familiar Papillary Thyroid Carcinoma in a Large Brazilian Family Is Not Associated with Succinate Dehydrogenase Defects. 2016 Jul 3
15 27528759 Isocitrate dehydrogenase (IDH), succinate dehydrogenase (SDH), fumarate hydratase (FH): three players for one phenotype in cancer? 2016 Aug 15 4
16 27587393 The Assembly Factor SDHAF2 Is Dispensable for Flavination of the Catalytic Subunit of Mitochondrial Complex II in Breast Cancer Cells. 2016 Oct 7 1
17 25328978 Instability of succinate dehydrogenase in SDHD polymorphism connects reactive oxygen species production to nuclear and mitochondrial genomic mutations in yeast. 2015 Mar 1 1
18 25435987 Alternative splicing isoform in succinate dehydrogenase complex, subunit C causes downregulation of succinate-coenzyme Q oxidoreductase activity in mitochondria. 2015 Jan 1
19 25985299 Oxygen concentration controls epigenetic effects in models of familial paraganglioma. 2015 4
20 26472283 Inactivation of SDH and FH cause loss of 5hmC and increased H3K9me3 in paraganglioma/pheochromocytoma and smooth muscle tumors. 2015 Nov 17 4
21 26522426 Loss of succinate dehydrogenase activity results in dependency on pyruvate carboxylation for cellular anabolism. 2015 Nov 2 4
22 26585387 NADP(+)-IDH Mutations Promote Hypersuccinylation that Impairs Mitochondria Respiration and Induces Apoptosis Resistance. 2015 Nov 19 2
23 24595825 Succinate dehydrogenase subunit B mutations modify human neuroblastoma cell metabolism and proliferation. 2014 Jun 1
24 24678033 Computational and experimental insight into the molecular mechanism of carboxamide inhibitors of succinate-ubquinone oxidoreductase. 2014 Jul 2
25 25004247 Germline FH mutations presenting with pheochromocytoma. 2014 Oct 4
26 23380393 Emerging concepts in the flavinylation of succinate dehydrogenase. 2013 May 4
27 23451094 High-throughput screening for growth inhibitors using a yeast model of familial paraganglioma. 2013 2
28 23453781 Succinate dehydrogenase: the complex roles of a simple enzyme. 2013 Jun 2
29 23714463 Connecting molecular pathways to hereditary cancer risk syndromes. 2013 2
30 24086109 HIF1A reduces acute lung injury by optimizing carbohydrate metabolism in the alveolar epithelium. 2013 Sep 4
31 22889736 Succinate dehydrogenase (SDHx) mutations in pituitary tumors: could this be a new role for mitochondrial complex II and/or Krebs cycle defects? 2012 Dec 2
32 21123035 Abnormalities in the tricarboxylic acid (TCA) cycle in the brains of schizophrenia patients. 2011 Mar 1
33 20592014 Mutation of SDHB is a cause of hypoxia-related high-altitude paraganglioma. 2010 Aug 15 1
34 20964315 Mutations in the Saccharomyces cerevisiae succinate dehydrogenase result in distinct metabolic phenotypes revealed through (1)H NMR-based metabolic footprinting. 2010 Dec 3 1
35 19368708 The first Dutch SDHB founder deletion in paraganglioma-pheochromocytoma patients. 2009 Apr 15 2
36 19628817 SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma. 2009 Aug 28 2
37 19778456 No evidence for promoter region methylation of the succinate dehydrogenase and fumarate hydratase tumour suppressor genes in breast cancer. 2009 Sep 25 4
38 18519664 Cells silenced for SDHB expression display characteristic features of the tumor phenotype. 2008 Jun 1 1
39 17325041 Cell-permeating alpha-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells. 2007 May 5
40 17520677 Increased HIF1 alpha in SDH and FH deficient tumors does not cause microsatellite instability. 2007 Sep 15 1
41 15652751 Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase. 2005 Jan 4
42 12612654 A role for mitochondrial enzymes in inherited neoplasia and beyond. 2003 Mar 2
43 2384736 Low succinate dehydrogenase (SDH) activity in a patient with a hereditary myopathy with paroxysmal myoglobinuria. 1990 Jul 1