Acetyl Coenzyme A

pyruvate dehydrogenase phosphatase catalytic subunit 1 ; Homo sapiens







36 Article(s)
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Pub. Year
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1 33675030 Reprogramming of glucose metabolism of cumulus cells and oocytes and its therapeutic significance. 2022 Mar 2
2 35315437 MAPK signalling-induced phosphorylation and subcellular translocation of PDHE1α promotes tumour immune evasion. 2022 Mar 2
3 33725483 Rheb mediates neuronal-activity-induced mitochondrial energetics through mTORC1-independent PDH activation. 2021 Mar 22 2
4 33809182 A Novel Therapeutic Target, BACH1, Regulates Cancer Metabolism. 2021 Mar 12 2
5 31958319 Soluble (pro)renin receptor increased by hypoxia maintains oxidative metabolism in trophoblasts. 2020 Apr 1
6 30881593 Adaptations in Protein Expression and Regulated Activity of Pyruvate Dehydrogenase Multienzyme Complex in Human Systolic Heart Failure. 2019 2
7 31582221 Prolonged hypoxia decreases nuclear pyruvate dehydrogenase complex and regulates the gene expression. 2019 Nov 26 3
8 31623369 Differential Mechanism of ATP Production Occurs in Response to Succinylacetone in Colon Cancer Cells. 2019 Oct 3 2
9 29610354 Observation of acetyl phosphate formation in mammalian mitochondria using real-time in-organelle NMR metabolomics. 2018 Apr 17 2
10 27641336 The microRNA-182-PDK4 axis regulates lung tumorigenesis by modulating pyruvate dehydrogenase and lipogenesis. 2017 Feb 16 1
11 28512002 Cell-surface G-protein-coupled receptors for tumor-associated metabolites: A direct link to mitochondrial dysfunction in cancer. 2017 Aug 1
12 27179453 Metabolic reprogramming by the pyruvate dehydrogenase kinase-lactic acid axis: Linking metabolism and diverse neuropathophysiologies. 2016 Sep 1
13 26137220 Metabolic plasticity maintains proliferation in pyruvate dehydrogenase deficient cells. 2015 3
14 24395925 Obesity and lipid stress inhibit carnitine acetyltransferase activity. 2014 Apr 2
15 25088999 Prolyl-hydroxylase PHD3 interacts with pyruvate dehydrogenase (PDH)-E1β and regulates the cellular PDH activity. 2014 Aug 22 1
16 25152236 SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells. 2014 Nov 3
17 22508045 Influence of dichloroacetate (DCA) on lactate production and oxygen consumption in neuroblastoma cells: is DCA a suitable drug for neuroblastoma therapy? 2012 2
18 21596918 The relationship between human skeletal muscle pyruvate dehydrogenase phosphatase activity and muscle aerobic capacity. 2011 Aug 2
19 19517265 Four novel PDHA1 mutations in pyruvate dehydrogenase deficiency. 2009 Dec 2
20 19605760 Prior heavy exercise elevates pyruvate dehydrogenase activity and muscle oxygenation and speeds O2 uptake kinetics during moderate exercise in older adults. 2009 Sep 1
21 19639391 A cognitively normal PDH-deficient 18-year-old man carrying the R263G mutation in the PDHA1 gene. 2009 Dec 2
22 17555402 Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1. 2007 Jul 1 1
23 16517405 HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. 2006 Mar 2
24 14966024 Pyruvate dehydrogenase activation and kinase expression in human skeletal muscle during fasting. 2004 Jun 1
25 20641814 Hyperpolarized sodium 1-[13C]pyruvate 2004 1
26 14641042 Regulation of PDH activity and isoform expression: diet and exercise. 2003 Dec 2
27 12467461 Nonlinear dynamics of eucaryotic pyruvate dehydrogenase multienzyme complex: decarboxylation rate, oscillations, and multiplicity. 2002 Nov-Dec 2
28 10662717 Effect of induced metabolic alkalosis on human skeletal muscle metabolism during exercise. 2000 Feb 1
29 10826498 Regulation by carnitine of myocardial fatty acid and carbohydrate metabolism under normal and pathological conditions. 2000 Apr 1
30 11001755 Effects of PDH activation by dichloroacetate in human skeletal muscle during exercise in hypoxia. 2000 Oct 1
31 11102541 Analysis of exonic mutations leading to exon skipping in patients with pyruvate dehydrogenase E1 alpha deficiency. 2000 Dec 2
32 10516124 Effect of induced metabolic acidosis on human skeletal muscle metabolism during exercise. 1999 Oct 1
33 9562476 Possible role of tau protein kinases in pathogenesis of Alzheimer's disease. 1998 Jan-Feb 2
34 9816911 [Involvement of tau protein kinase in amyloid-beta-induced neurodegeneration]. 1998 Oct 1
35 7929613 Glucose fatty acid interactions and the regulation of glucose disposal. 1994 2
36 2249846 A testis-specific form of the human pyruvate dehydrogenase E1 alpha subunit is coded for by an intronless gene on chromosome 4. 1990 Oct 2