| 1 |
33675030 | Reprogramming of glucose metabolism of cumulus cells and oocytes and its therapeutic significance. | 2022 Mar |
2 |
| 2 |
35138247 | Pyruvate:ferredoxin oxidoreductase and low abundant ferredoxins support aerobic photomixotrophic growth in cyanobacteria. | 2022 Feb 9 |
2 |
| 3 |
35315437 | MAPK signalling-induced phosphorylation and subcellular translocation of PDHE1α promotes tumour immune evasion. | 2022 Mar |
2 |
| 4 |
32737469 | Pharmacologically inhibiting phosphoglycerate kinase 1 for glioma with NG52. | 2021 Apr |
1 |
| 5 |
33809182 | A Novel Therapeutic Target, BACH1, Regulates Cancer Metabolism. | 2021 Mar 12 |
1 |
| 6 |
34020698 | Lactate oxidative phosphorylation by annulus fibrosus cells: evidence for lactate-dependent metabolic symbiosis in intervertebral discs. | 2021 May 21 |
1 |
| 7 |
34156298 | Hyperpolarized 13C MR Spectroscopy Depicts in Vivo Effect of Exercise on Pyruvate Metabolism in Human Skeletal Muscle. | 2021 Sep |
1 |
| 8 |
34375613 | The requirement for pyruvate dehydrogenase in leukemogenesis depends on cell lineage. | 2021 Sep 7 |
1 |
| 9 |
32319629 | Conditional knockout of pyruvate dehydrogenase in mouse pancreatic β‑cells causes morphological and functional changes. | 2020 Apr |
1 |
| 10 |
30881593 | Adaptations in Protein Expression and Regulated Activity of Pyruvate Dehydrogenase Multienzyme Complex in Human Systolic Heart Failure. | 2019 |
2 |
| 11 |
29695298 | Pyruvate is a prospective alkalizer to correct hypoxic lactic acidosis. | 2018 Apr 26 |
2 |
| 12 |
27641336 | The microRNA-182-PDK4 axis regulates lung tumorigenesis by modulating pyruvate dehydrogenase and lipogenesis. | 2017 Feb 16 |
1 |
| 13 |
28512002 | Cell-surface G-protein-coupled receptors for tumor-associated metabolites: A direct link to mitochondrial dysfunction in cancer. | 2017 Aug |
1 |
| 14 |
28564592 | Alteration of mitochondrial protein PDHA1 in Lewy body disease and PARK14. | 2017 Aug 5 |
1 |
| 15 |
26679997 | Pro-inflammatory Macrophages Sustain Pyruvate Oxidation through Pyruvate Dehydrogenase for the Synthesis of Itaconate and to Enable Cytokine Expression. | 2016 Feb 19 |
2 |
| 16 |
26848621 | Src drives the Warburg effect and therapy resistance by inactivating pyruvate dehydrogenase through tyrosine-289 phosphorylation. | 2016 May 3 |
2 |
| 17 |
27144334 | Mutant IDH1 expression is associated with down-regulation of monocarboxylate transporters. | 2016 Jun 7 |
1 |
| 18 |
27179453 | Metabolic reprogramming by the pyruvate dehydrogenase kinase-lactic acid axis: Linking metabolism and diverse neuropathophysiologies. | 2016 Sep |
1 |
| 19 |
25644430 | SMYD1 and G6PD modulation are critical events for miR-206-mediated differentiation of rhabdomyosarcoma. | 2015 |
1 |
| 20 |
25745810 | Ethanol production by engineered thermophiles. | 2015 Jun |
4 |
| 21 |
25973318 | DCA promotes progression of neuroblastoma tumors in nude mice. | 2015 |
1 |
| 22 |
26137220 | Metabolic plasticity maintains proliferation in pyruvate dehydrogenase deficient cells. | 2015 |
2 |
| 23 |
25088999 | Prolyl-hydroxylase PHD3 interacts with pyruvate dehydrogenase (PDH)-E1β and regulates the cellular PDH activity. | 2014 Aug 22 |
1 |
| 24 |
25104357 | Tyr-301 phosphorylation inhibits pyruvate dehydrogenase by blocking substrate binding and promotes the Warburg effect. | 2014 Sep 19 |
1 |
| 25 |
25152236 | SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells. | 2014 Nov |
5 |
| 26 |
25243911 | Glioma cells with the IDH1 mutation modulate metabolic fractional flux through pyruvate carboxylase. | 2014 |
2 |
| 27 |
21774012 | Simultaneous investigation of cardiac pyruvate dehydrogenase flux, Krebs cycle metabolism and pH, using hyperpolarized [1,2-(13)C2]pyruvate in vivo. | 2012 Feb |
1 |
| 28 |
22508045 | Influence of dichloroacetate (DCA) on lactate production and oxygen consumption in neuroblastoma cells: is DCA a suitable drug for neuroblastoma therapy? | 2012 |
2 |
| 29 |
20799252 | Validation of the in vivo assessment of pyruvate dehydrogenase activity using hyperpolarised 13C MRS. | 2011 Feb |
4 |
| 30 |
21596918 | The relationship between human skeletal muscle pyruvate dehydrogenase phosphatase activity and muscle aerobic capacity. | 2011 Aug |
2 |
| 31 |
21941478 | A comprehensive metabolic profile of cultured astrocytes using isotopic transient metabolic flux analysis and C-labeled glucose. | 2011 |
1 |
| 32 |
20699381 | A combined proteomics and metabolomics profiling of gastric cardia cancer reveals characteristic dysregulations in glucose metabolism. | 2010 Dec |
1 |
| 33 |
19517265 | Four novel PDHA1 mutations in pyruvate dehydrogenase deficiency. | 2009 Dec |
1 |
| 34 |
19639391 | A cognitively normal PDH-deficient 18-year-old man carrying the R263G mutation in the PDHA1 gene. | 2009 Dec |
2 |
| 35 |
19934362 | Cardiovascular applications of hyperpolarized contrast media and metabolic tracers. | 2009 Dec |
1 |
| 36 |
19081062 | Snapshots of catalysis in the E1 subunit of the pyruvate dehydrogenase multienzyme complex. | 2008 Dec 10 |
1 |
| 37 |
17384007 | Diagnostic accuracy of blood lactate-to-pyruvate molar ratio in the differential diagnosis of congenital lactic acidosis. | 2007 May |
1 |
| 38 |
17521432 | Metabolic compartmentalization in the human cortex and hippocampus: evidence for a cell- and region-specific localization of lactate dehydrogenase 5 and pyruvate dehydrogenase. | 2007 May 23 |
1 |
| 39 |
17555402 | Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1. | 2007 Jul 1 |
1 |
| 40 |
16517405 | HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. | 2006 Mar |
1 |
| 41 |
15736311 | Pyruvate dehydrogenase and pyruvate dehydrogenase kinase expression in non small cell lung cancer and tumor-associated stroma. | 2005 Jan |
2 |
| 42 |
14660628 | Chronic high glucose lowers pyruvate dehydrogenase activity in islets through enhanced production of long chain acyl-CoA: prevention of impaired glucose oxidation by enhanced pyruvate recycling through the malate-pyruvate shuttle. | 2004 Feb 27 |
1 |
| 43 |
14702404 | Azorhizobium caulinodans electron-transferring flavoprotein N electrochemically couples pyruvate dehydrogenase complex activity to N2 fixation. | 2004 Jan |
1 |
| 44 |
15169745 | Rapid upregulation of pyruvate dehydrogenase kinase activity in human skeletal muscle during prolonged exercise. | 2004 Oct |
2 |
| 45 |
15220302 | Effects of 7 wk of endurance training on human skeletal muscle metabolism during submaximal exercise. | 2004 Dec |
1 |
| 46 |
20641814 | Hyperpolarized sodium 1-[13C]pyruvate | 2004 |
2 |
| 47 |
11991544 | Regulation of pyruvate dehydrogenase (PDH) activity in human skeletal muscle during exercise. | 2002 Apr |
1 |
| 48 |
12356901 | Effects of respiratory alkalosis on human skeletal muscle metabolism at the onset of submaximal exercise. | 2002 Oct 1 |
1 |
| 49 |
12467446 | Metabolic control analysis of eucaryotic pyruvate dehydrogenase multienzyme complex. | 2002 Nov-Dec |
3 |
| 50 |
12467461 | Nonlinear dynamics of eucaryotic pyruvate dehydrogenase multienzyme complex: decarboxylation rate, oscillations, and multiplicity. | 2002 Nov-Dec |
3 |