Carbamazepine

epoxide hydrolase 1 ; Homo sapiens







27 Article(s)
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Pub. Year
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1 33217013 Evaluation of clinical and genetic factors in the population pharmacokinetics of carbamazepine. 2021 Jun 2
2 33671323 Pharmacokinetics of the CYP3A4 and CYP2B6 Inducer Carbamazepine and Its Drug-Drug Interaction Potential: A Physiologically Based Pharmacokinetic Modeling Approach. 2021 Feb 17 2
3 34373022 Association of EPHX1 polymorphisms with plasma concentration of carbamazepine in epileptic patients: Systematic review and meta-analysis. 2021 Sep 6
4 34411648 ABCB1 c.3435C > T and EPHX1 c.416A > G polymorphisms influence plasma carbamazepine concentration, metabolism, and pharmacoresistance in epileptic patients. 2021 Dec 30 5
5 34612084 Relevance of NR1I2 variants on carbamazepine therapy in Mexican Mestizos with epilepsy at a tertiary-care hospital. 2021 Oct 2
6 31164100 Different EPHX1 methylation levels in promoter area between carbamazepine-resistant epilepsy group and carbamazepine-sensitive epilepsy group in Chinese population. 2019 Jun 4 10
7 31650507 Association between EPHX1 polymorphisms and carbamazepine metabolism in epilepsy: a meta-analysis. 2019 Dec 4
8 27276192 Effects of EPHX1 and CYP3A4*22 genetic polymorphisms on carbamazepine metabolism and drug response among Tunisian epileptic patients. 2016 Mar 5
9 26314341 Association between PK/PD-involved gene polymorphisms and carbamazepine-individualized therapy. 2015 2
10 26555147 Polymorphic Variants of SCN1A and EPHX1 Influence Plasma Carbamazepine Concentration, Metabolism and Pharmacoresistance in a Population of Kosovar Albanian Epileptic Patients. 2015 3
11 24406279 Pharmacogenetic potential biomarkers for carbamazepine adverse drug reactions and clinical response. 2014 1
12 24817818 Effects of EPHX1 and CYP3A4 polymorphisms on carbamazepine metabolism in epileptic patients. 2014 4
13 24861996 Association of ABCB1, CYP3A4, EPHX1, FAS, SCN1A, MICA, and BAG6 polymorphisms with the risk of carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis in Chinese Han patients with epilepsy. 2014 Aug 6
14 25495409 Effects of major transporter and metabolizing enzyme gene polymorphisms on carbamazepine metabolism in Chinese patients with epilepsy. 2014 1
15 23252947 Association of carbamazepine major metabolism and transport pathway gene polymorphisms and pharmacokinetics in patients with epilepsy. 2013 Jan 2
16 24125961 Effects of EPHX1, SCN1A and CYP3A4 genetic polymorphisms on plasma carbamazepine concentrations and pharmacoresistance in Chinese patients with epilepsy. 2013 Dec 2
17 22188362 Association of polymorphisms in EPHX1, UGT2B7, ABCB1, ABCC2, SCN1A and SCN2A genes with carbamazepine therapy optimization. 2012 Jan 5
18 27713373 Update on the Genetic Polymorphisms of Drug-Metabolizing Enzymes in Antiepileptic Drug Therapy. 2010 Aug 20 1
19 19127076 Carbamazepine hypersensitivity syndrome triggered by a human herpes virus reactivation in a genetically predisposed patient. 2009 2
20 19364907 The expression of human microsomal epoxide hydrolase is predominantly driven by a genetically polymorphic far upstream promoter. 2009 Jul 2
21 19620853 Genetic variants in microsomal epoxide hydrolase influence carbamazepine dosing. 2009 Jul-Aug 4
22 17375979 The role of pharmacogenetics in the metabolism of antiepileptic drugs: pharmacokinetic and therapeutic implications. 2007 1
23 15692831 Haplotype structures of EPHX1 and their effects on the metabolism of carbamazepine-10,11-epoxide in Japanese epileptic patients. 2005 Mar 1
24 9406998 Tissue-specific expression and alternative splicing of human microsomal epoxide hydrolase. 1997 Nov 1
25 7503783 Genetic analysis of microsomal epoxide hydrolase in patients with carbamazepine hypersensitivity. 1995 Oct 26 2
26 7503784 Kinetic parameters of lymphocyte microsomal epoxide hydrolase in carbamazepine hypersensitive patients. Assessment by radiometric HPLC. 1995 Oct 26 2
27 7917777 Lymphocyte microsomal epoxide hydrolase in patients on carbamazepine therapy. 1994 Jun 3